Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jaki R. Tamboli"'
Autor:
Chandrakant Bagul, Garikapati Koteswara Rao, Immadi Veena, Ravindra Kulkarni, Jaki R. Tamboli, Ravikumar Akunuri, Siddiq Pasha Shaik, Manika Pal-Bhadra, Ahmed Kamal
Publikováno v:
Molecular diversity.
A library of benzimidazole briged pyrazolo[1,5-a]pyrimidine (6a-q) was designed, synthesized and subjected for evaluation for cytotoxic potential. Antiproliferative activity, ranging from 3.1-51.5 μM, was observed against a panel of cancer cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12319ae0a6c3da01e94167ddb1b5f1de
https://pubmed.ncbi.nlm.nih.gov/36114912
https://pubmed.ncbi.nlm.nih.gov/36114912
Autor:
Manika Pal-Bhadra, Venkata Krishna Kanth Makani, Chandrakant Bagul, Jaki R. Tamboli, Garikapati Koteswara Rao, Ahmed Kamal
Publikováno v:
MedChemComm. 8:1810-1816
A series of pyrazolo[1,5-a]pyrimidines substituted at C5 with 1-phenylprop-2-en-1-one (6a-q) and 3-phenylprop-2-en-1-one (7a-k) was synthesized and evaluated for antiproliferative activity. Among them, 6h was found to be the most active compound agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590d56e8abb4d0f7ecb19d479f29cf41
https://doi.org/10.1039/c7md00193b
https://doi.org/10.1039/c7md00193b
Autor:
Pranjal Sarma, Syed Farooq Adil, M. Janaki Ramaiah, Raksha Ganesh, Ahmed Kamal, S.N.C.V.L. Pushpavalli, Utpal Bhadra, Jaki R. Tamboli, Manika Pal-Bhadra
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6414-6426
A series of new conjugates of quinazolino linked 4β-amidopodophyllotoxins 10aa–af and 10ba–bf were synthesized and evaluated for their anticancer activity against human pancreatic carcinoma (Panc-1) as well as breast cancer cell lines such as MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92efa90242d67a9a05b6b4ed9480167
https://doi.org/10.1016/j.bmc.2013.08.051
https://doi.org/10.1016/j.bmc.2013.08.051
Autor:
Syed Farooq Adil, Ahmed Kamal, Jaki R. Tamboli, V. Lakshma Nayak, Sistla Ramakrishna, M.V.P.S. Vishnuvardhan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3208-3215
A series of pyrazolo[1,5-a]pyrimidine linked 2-aminobenzothizole conjugates (6a–t) were synthesized and evaluated for their anticancer activity against five human cancer cell lines. Among them two compounds 6p and 6m showed significant anticancer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e618b2301d39ec114544790be069005
https://doi.org/10.1016/j.bmcl.2013.03.129
https://doi.org/10.1016/j.bmcl.2013.03.129
Autor:
Paidakula Suresh, Adla Mallareddy, Nishant Jain, Papagari Venkat Reddy, Thokhir Basha Shaik, Jaki R. Tamboli, Ahmed Kamal, Banala Ashwini Kumar, Shasi V. Kalivendi, P. Raju
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2349-2358
A series of novel conjugates of 4-aza-2,3-didehydropodophyllotoxins ( 11a – w ) were synthesized by a straightforward one-step multicomponent synthesis that demonstrated cytotoxicity against five human cancer cell lines (breast, oral, colon, lung a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941efcf12b9297e4925f52c5519a30dc
https://doi.org/10.1016/j.bmc.2011.02.020
https://doi.org/10.1016/j.bmc.2011.02.020
Publikováno v:
Letters in Drug Design & Discovery. 7:665-673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8e47ea2f91ec01997672474d08fa838
https://doi.org/10.2174/157018010792929559
https://doi.org/10.2174/157018010792929559
Publikováno v:
Letters in Drug Design & Discovery. 6:201-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b537aab71e8b6805dfb22b732e3b00a9
https://doi.org/10.2174/157018009787847855
https://doi.org/10.2174/157018009787847855
Publikováno v:
Letters in Drug Design & Discovery. 5:261-270
A series of phthalimido-dihydropyrimidones (19a-l) and naphthalimido-dihydropyrimidones (23a-l) have been synthesized and some representative compounds have been evaluated for their in vitro anticancer activity. Compounds 19d, 19f and 19j are selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fe4387f9b0c932db4990f81ce101de
https://doi.org/10.2174/157018008784619933
https://doi.org/10.2174/157018008784619933
Autor:
Jaki R. Tamboli, M. Janaki Ramaiah, A. Lavanya, Utpal Bhadra, Ahmed Kamal, Manika Pal-Bhadra, V. Haritha, Nibedita Patel, S.N.C.V.L. Pushpavalli, Kaustav Bhadra
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(20)
It has previously been shown that anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates activate p53 and cause apoptosis in cervical cancer cells such as HeLa and SiHa. Here we establish the role of these conjugates in activating p53 pathway by phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea2c8c84020f6889965419b6b73b51b
https://pubmed.ncbi.nlm.nih.gov/23992861
https://pubmed.ncbi.nlm.nih.gov/23992861
Autor:
Ahmed Kamal, V. Lakshma Nayak, M.V.P.S. Vishnuvardhan, Jaki R. Tamboli, Sistla Ramakrishna, Syed Farooq Adil
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(1)
A series of different heteroaromatic linked 4β-amidopodophyllotoxin conjugates (16a-i, 17a-i and 18a-d) were synthesized and evaluated for anticancer activity against five human cancer cell lines. Among the series, one of the compound 17g showed sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0571037339c778f48293724970763b49
https://pubmed.ncbi.nlm.nih.gov/23182091
https://pubmed.ncbi.nlm.nih.gov/23182091