Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jake Scott"'
Autor:
Carolyn Chu, Kaiming Tao, Vinie Kouamou, Ava Avalos, Jake Scott, Philip M. Grant, Soo-Yon Rhee, Suzanne M. McCluskey, Michael R. Jordan, Rebecca L. Morgan, Robert W. Shafer
Publikováno v:
Viruses, Vol 16, Iss 3, p 399 (2024)
Background: Dolutegravir (DTG) is a cornerstone of global antiretroviral (ARV) therapy (ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding the risk of emergent integrase strand transfer inhibitor (INSTI) d
Externí odkaz:
https://doaj.org/article/34d25c7a03884a529279d268af3e72b0
Autor:
Mathew Clement, Kristin Ladell, Kelly L Miners, Morgan Marsden, Lucy Chapman, Anna Cardus Figueras, Jake Scott, Robert Andrews, Simon Clare, Valeriia V Kriukova, Ksenia R Lupyr, Olga V Britanova, David R Withers, Simon A Jones, Dmitriy M Chudakov, David A Price, Ian R Humphreys
Publikováno v:
eLife, Vol 12 (2023)
Inhibitory CD4+ T cells have been linked with suboptimal immune responses against cancer and pathogen chronicity. However, the mechanisms that underpin the development of these regulatory cells, especially in the context of ongoing antigen exposure,
Externí odkaz:
https://doaj.org/article/2ebd05a7a8214cc583977dd47ed817fc
Autor:
Jessica Ferguson, Joelle I. Rosser, Orlando Quintero, Jake Scott, Aruna Subramanian, Mohammad Gumma, Angela Rogers, Shanthi Kappagoda
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 8, Pp 1679-1685 (2020)
Limited data are available on the clinical presentation and outcomes of coronavirus disease (COVID-19) patients in the United States hospitalized under normal-caseload or nonsurge conditions. We retrospectively studied 72 consecutive adult patients h
Externí odkaz:
https://doaj.org/article/05d454114659413b93cb86b4982583be
Autor:
Emma Jones, Andrew Godkin, Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown prom
Externí odkaz:
https://doaj.org/article/03253b8693d64d3c84a6f9eeb342088e
Publikováno v:
Case Reports in Infectious Diseases, Vol 2020 (2020)
A young woman with mixed connective tissue disease complicated by erosive arthritis, secondary hypogammaglobulinemia due to rituximab, and a history of many infectious complications developed multiple nonhealing wounds, polyarticular joint pain, and
Externí odkaz:
https://doaj.org/article/481ef4f75da14fb9a2f5a7b159a5043a
Publikováno v:
CASE : Cardiovascular Imaging Case Reports
Graphical abstract
Highlights • Native aortic root thrombus is a life-threatening complication in patients with HLHS. • Echo evaluation of the native aortic root is an important consideration. • Echo monitoring is a useful tool for assessm
Highlights • Native aortic root thrombus is a life-threatening complication in patients with HLHS. • Echo evaluation of the native aortic root is an important consideration. • Echo monitoring is a useful tool for assessm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefaf2aedc8ba0f9b337957e5d91a1a9
https://doi.org/10.1016/j.case.2021.07.007
https://doi.org/10.1016/j.case.2021.07.007
Publikováno v:
Current topics in microbiology and immunology. 436
Improving the anti-tumour T cell response as a consequence of immunotherapy can result in eradication of tumour burden, however, the majority of patients fail with current treatment regimens and so novel immunotherapies with greater efficacy and impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdd94880e3bfa87485f0e3842fb9006c
https://pubmed.ncbi.nlm.nih.gov/36243853
https://pubmed.ncbi.nlm.nih.gov/36243853
Autor:
Jake Scott, Stan Deresinski
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
Reducing the overuse of antimicrobials is imperative for the sake of minimizing antimicrobial-associated adverse effects, optimizing resource utilization, and curtailing the rise in multidrug-resistant organisms. Biomarkers reflect the host responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05eba875070045715beeb224eafed220
https://pubmed.ncbi.nlm.nih.gov/36096429
https://pubmed.ncbi.nlm.nih.gov/36096429
Autor:
Joelle I. Rosser, Aruna Subramanian, Jake Scott, Orlando Quintero, Jessica Ferguson, Shanthi Kappagoda, Mohammad Gumma, Angela J. Rogers
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 8, Pp 1679-1685 (2020)
Emerging Infectious Diseases
Emerging Infectious Diseases
Limited data are available on the clinical presentation and outcomes of coronavirus disease (COVID-19) patients in the United States hospitalized under normal-caseload or nonsurge conditions. We retrospectively studied 72 consecutive adult patients h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4305bf3238d03acaf0d6b28edb463ef
https://wwwnc.cdc.gov/eid/article/26/8/20-1776_article
https://wwwnc.cdc.gov/eid/article/26/8/20-1776_article
Autor:
Andrew James Godkin, Andrew Blainey, Anja Bloom, Sarah Nicol Lauder, Jake Scott, Awen Gallimore, Emma Jones, Molly Browne, E. Hughes, Michelle Somerville, Ann Ager, Kathryn Smart
Publikováno v:
Cancer Immunology, Immunotherapy
Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7823a107573420715c577954336cabb3
https://doi.org/10.1007/s00262-020-02603-x
https://doi.org/10.1007/s00262-020-02603-x