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Variable Landscape of PD-L1 Expression in Breast Carcinoma as Detected by the DAKO 22C3 Immunohistochemistry Assay

Autor: Natalie Danziger, Ethan S Sokol, Ryon P Graf, Matthew C Hiemenz, Jake Maule, Vamsi Parimi, Carlo Palmieri, Lajos Pusztai, Jeffrey S Ross, Richard S P Huang

Publikováno v: The Oncologist. 28:319-326

Background In 2020, pembrolizumab was approved as a therapy for triple-negative breast cancer (TNBC) with the companion diagnostic DAKO 22C3 programmed death ligand-1 (PD-L1) immunohistochemistry assay. The study aimed to determine the landscape of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::933a9d43ae67b7b16da64a54684bde79
https://doi.org/10.1093/oncolo/oyad025

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Plasma cells are essentially absent in the luminal gastrointestinal tract of patients with 'complete' 22q11.2 deletion syndrome (DiGeorge syndrome)

Autor: Shannon J. McCall, Avani A. Pendse, Jake Maule, Jadee L. Neff

Publikováno v: Human Pathology. 117:1-8

Summary Gastrointestinal symptoms are commonly reported in patients with 22q11.2 deletion syndrome or DiGeorge syndrome (DGS) in addition to the dominant cardiac manifestations and immunodeficiency. But literature providing specific morphologic detai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8407153fecfba54f7ce7fa9cf76b27
https://doi.org/10.1016/j.humpath.2021.08.002

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Myeloid neoplasms in the setting of chronic lymphocytic leukaemia/chronic lymphocytic leukaemia-like disease: a clinicopathological study of 66 cases comparing cases with prior history of treatment to those without

Autor: Catherine Luedke, Jerald Z. Gong, Lian-He Yang, Yue Zhao, Rachel Jug, Jenna McCracken, Jonathan Galeotti, Jake Maule, Imran Siddiqi, Endi Wang, Chuanyi M. Lu

Publikováno v: Journal of Clinical Pathology. 75:292-301

AimsMyeloid neoplasms occur in the setting of chronic lymphocytic leukaemia (CLL)/CLL-like disease. The underlying pathogenesis has not been elucidated.MethodsRetrospectively analysed 66 cases of myeloid neoplasms in patients with CLL/CLL-like diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acb080882697af521094adbc160b09a
https://doi.org/10.1136/jclinpath-2020-207334

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Masson’s tumor presenting as a left frontal intraparenchymal hemorrhage resulting in severe expressive aphasia during pregnancy: case report

Autor: Jordan M. Komisarow, Jenna S. Hynes, Eric W. Sankey, Courtney Mitchell, Andrew S. Griffin, Jake Maule, Allan H. Friedman, Sarah K. Dotters-Katz

Publikováno v: Journal of Neurosurgery. 134:189-196

Intravascular papillary endothelial hyperplasia (IPEH), commonly known as Masson’s tumor, is a benign lesion that manifests as an excessive proliferation of endothelial cells within a vessel wall. IPEH is extremely rare in the brain, with only 36 i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d84a1014e662986e921b80fcb45ef8e
https://doi.org/10.3171/2019.8.jns191767

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Myeloid neoplasms in the setting of sickle cell disease: an intrinsic association with the underlying condition rather than a coincidence; report of 4 cases and review of the literature

Autor: Sarah Rapisardo, Anand S. Lagoo, Endi Wang, Yue Zhao, Chad M. McCall, Jadee L. Neff, Lian-He Yang, Jake Maule, Regina D. Crawford, Yang Li

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 32(12)

Myeloid neoplasms occasionally occur in patients with sickle cell disease, and the underlying connection between the two diseases is unclear. Herein, we retrospectively analyzed four cases of sickle cell disease patients who developed myeloid neoplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55931c4bcf0eb195e82fa3d8abccb3a3
https://pubmed.ncbi.nlm.nih.gov/31371806

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Incidental finding of abdominal splenosis with mononucleated cell infiltration leading to a diagnosis of acute myeloid leukemia

Autor: Endi Wang, Jake Maule, Yue Zhao, Jalen Xing, Jenna McCracken

Publikováno v: Pathology - Research and Practice. 216:152818

Splenosis refers to ectopic splenic implants that are often found incidentally years after splenic rupture/splenectomy, and the nodules of splenosis are usually small, less than 3 cm for the majority. We report a case of splenosis with a 5-centimeter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f095bf7ae1640618f040f761fab3912
https://doi.org/10.1016/j.prp.2020.152818

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Sequential development of human herpes virus 8-positive diffuse large B-cell lymphoma and chronic myelomonocytic leukemia in a 59 year old female patient with hemoglobin SC disease

Autor: Weihong Yang, Catherine Rehder, Chad M. McCall, Yue Zhao, Yang Li, Lian-He Yang, Jadee L. Neff, Endi Wang, Jake Maule, Tie Hao

Publikováno v: Pathology - Research and Practice. 215:152704

Hematolymphoid neoplasms, including lymphoma and myeloid neoplasms, can occur in patients with sickle cell disease (SCD) or equivalent hemoglobinopathy, but an underlying connection between the two conditions has yet to be fully determined. Herein, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26757b720b85200433ec4a62b4c08d4e
https://doi.org/10.1016/j.prp.2019.152704

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Immune responses, not promoter inactivation, are responsible for decreased long-term expression following plasmid gene transfer into skeletal muscle

Autor: A Poole, Jill McMahon, Jake Maule, Keith Foster, R Kingston, Dominic J. Wells, E Damien, K E Wells

Publikováno v: FEBS Letters. 407:164-168

Long-term high-level in vivo gene expression appears to depend on the promoter chosen to drive the gene of choice. In many cases the promoter appears to `switch off' some time after in vivo gene transfer. We demonstrate that, following intramuscular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c23944da19ed4fd9af47b05e0f13c0e
https://doi.org/10.1016/s0014-5793(97)00329-3

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