Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jake K Soley"'
Autor:
Sarah L. Bevington, Remi Fiancette, Dominika W. Gajdasik, Peter Keane, Jake K. Soley, Claire M. Willis, Daniel J. L. Coleman, David R. Withers, Peter N. Cockerill
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cell immunological memory is established within days of an infection, but little is known about the in vivo changes in gene regulatory networks accounting for their ability to respond more efficiently to secondary infections. To decipher the timing
Externí odkaz:
https://doaj.org/article/2cd43fb377234afe9b4df748fcec3954
Autor:
Sky T. H. Ng, Conor M. Finlay, Jake K Soley, Simon Andrews, Sarah L Bevington, Claire Willis, Matthew R. Hepworth, Syed Murtuza Baker, Remi Fiancette, David R. Withers
Publikováno v:
Fiancette, R, Finlay, C M, Willis, C, Bevington, S L, Soley, J, Ng, S T H, Baker, S M, Andrews, S, Hepworth, M R & Withers, D R 2021, ' Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity ', Nature Immunology, vol. 22, no. 10, pp. 1245-1255 . https://doi.org/10.1038/s41590-021-01024-x
Innate lymphoid cells (ILCs) are guardians of mucosal immunity, yet the transcriptional networks that support their function remain poorly understood. We used inducible combinatorial deletion of key transcription factors (TFs) required for ILC develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7358db0f12c5aabd9beb491b0aaf8a7f
https://research.manchester.ac.uk/en/publications/d8b0a2e5-1aa5-4513-ba0a-b6e71e556135
https://research.manchester.ac.uk/en/publications/d8b0a2e5-1aa5-4513-ba0a-b6e71e556135
Autor:
Daniel J. L. Coleman, Remi Fiancette, Peter Keane, Jake K Soley, David R. Withers, Peter N. Cockerill, Claire Willis, Sarah L Bevington, Dominika W Gajdasik
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
T cell immunological memory is established within days of an infection, but little is known about the in vivo changes in gene regulatory networks accounting for their ability to respond more efficiently to secondary infections. To decipher the timing
Autor:
Dominika W Gajdasik, Jake K Soley, Saskia Tauch, Claire Willis, Sarah L Bevington, Veronika Matei-Rascu, David R. Withers, Peter Keane, Remi Fiancette, Peter N. Cockerill
Publikováno v:
The EMBO Journal
When dormant naïve T cells first become activated by antigen‐presenting cells, they express the autocrine growth factor IL‐2 which transforms them into rapidly dividing effector T cells. During this process, hundreds of genes undergo epigenetic