Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.

Autor: Jasmina Saric, Jia V Li, Yulan Wang, Jennifer Keiser, Jake G Bundy, Elaine Holmes, Jürg Utzinger

Publikováno v: PLoS Neglected Tropical Diseases, Vol 2, Iss 7, p e254 (2008)

BACKGROUND: Metabolic profiling holds promise with regard to deepening our understanding of infection biology and disease states. The objectives of our study were to assess the global metabolic responses to an Echinostoma caproni infection in the mou

Externí odkaz: https://doaj.org/article/1ef0ff96e9e140eaa761bb115c3aa10d

Ageing with elegans : a research proposal to map healthspan pathways

Autor: Michael Ristow, Péter Antal, Nadine Saul, Christopher Fang-Yen, Jake G. Bundy, Andres Metspalu, Liesbet Temmerman, Karsten Siems, Walter Luyten, Tina Smets, Francesca Cirulli, Patricia Martorell, Georg Fuellen, Liliane Schoofs, Suresh I. S. Rattan, Qingfei Liu, Bart P. Braeckman, Armand M. Leroi, Alicja Wolk, Markus Perola

Publikováno v: Luetyn, W, Antal, P, Braekman, B, Bundy, J, Cirulli, F, Fang-Yen, C, Fuellen, G, Leroi, A, Liu, Q, Martorell, P, Metspalu, A, Perola, M, Ristow, M, Saul, N, Schoofs, L, Siems, K, Temmerman, L, Smets, T, Wolk, A & Rattan, S 2016, ' Ageing with elegans : a research proposal to map healthspan pathways ', Biogerontology, vol. 17, no. 4, pp. 771-782 . https://doi.org/10.1007/s10522-016-9644-x
Biogerontology

Human longevity continues to increase world-wide, often accompanied by decreasing birth rates. As a larger fraction of the population thus gets older, the number of people suffering from disease or disability increases dramatically, presenting a majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d2ceae1cdc93e1a9e5ee483d98095d
http://hdl.handle.net/10138/224110

Differences in strategies to combat osmotic stress in Burkholderia cenocepacia elucidated by NMR-based metabolic profiling

Autor: Huw D. Williams, Volker Behrends, Jake G. Bundy

Publikováno v: Letters in Applied Microbiology. 52:619-625

Aims: To investigate mechanisms of osmotic tolerance in Burkholderia cenocepacia, a member of the B. cepacia complex (Bcc) of closely related strains, which is of clinical as well as environmental importance. Methods and Results: We employed NMR-base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d061848b70e9399599741f6c3637c059
https://doi.org/10.1111/j.1472-765x.2011.03050.x

WormJam: A consensusC. elegansMetabolic Reconstruction and Metabolomics Community and Workshop Series

Autor: Michael Witting, Sven Bergmann, Artur B. Lourenço, Filipe Cabreiro, Chintan Joshi, Christoph Kaleta, Toon Santermans, Paul R. Ebert, Varun B. Kothamachu, Manusnan Suriyalaksh, Paul D. Dobson, Juliette Pearce, Jake P. N. Hattwell, Pasquale Scarcia, Yu Nie, Aleksandra Zečić, Benjamin D. Towbin, Johannes Zimmermann, Nicolas Le Novère, Marta Artal-Sanz, Rob Jelier, Nicolas Rodriguez, Mary Ann Tuli, Reuben L. Smith, Horst Joachim Schirra, Hooman Hefzi, Ming Sheng, Abraham Mains, Jake G. Bundy, David Weinkove, Michel van Weeghel, Riekelt H. Houtkooper, Povilas Norvaisas, Olivia Casanueva, Nathan E. Lewis, Bart P. Braeckman, Cristian Riccio, Janna Hastings

Publikováno v: Hastings, Janna; Mains, Abraham; Artal-Sanz, Marta; Bergmann, Sven; Braeckman, Bart P.; Bundy, Jake; Cabreiro, Filipe; Dobson, Paul; Ebert, Paul; Hattwell, Jake; Hefzi, Hooman; Houtkooper, Riekelt H.; Jelier, Rob; Joshi, Chintan; Kothamachu, Varun B.; Lewis, Nathan; Lourenço, Artur Bastos; Nie, Yu; Norvaisas, Povilas; Pearce, Juliette; ... (2017). WormJam: A consensus C. elegans Metabolic Reconstruction and Metabolomics Community and Workshop Series. Worm, 6(2), e1373939. Taylor & Francis 10.1080/21624054.2017.1373939
Worm, 2017, Vol.6(2), pp.e1373939 [Peer Reviewed Journal]
Worm 6:e1373939 (2017)
Worm

A GENiE (EU COST action, www.worm-genie.eu) workshop was held at the Babraham Institute in Cambridge, UK on April 19 and 20, 2017, to discuss global challenges around Caenorhabditis elegans metabol...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b22514a5e005802955f3a73d95c3bc2
https://doi.org/10.1080/21624054.2017.1373939

High-throughput age synchronisation of Caenorhabditis elegans

Autor: Florian M. Geier, Jake G. Bundy, Andrew J. deMello, Xavier Casadevall i Solvas, Joshua B. Edel, Armand M. Leroi

Publikováno v: Chemical Communications. 47:9801

We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the basis of age and size. The separation mechanism takes advantage of phenotypic differences between 'adult' and 'juvenile' organisms and their behaviour in microfl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6c3b4ec362e82a4c47065917d93efe
https://doi.org/10.1039/c1cc14076k