Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jake D Jones"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Skin is a heterogeneous tissue that can undergo substantial structural and functional changes with age, disease, or following injury. Understanding how these changes impact the mechanical properties of skin requires three-dimensional (3D) quantificat
Externí odkaz:
https://doaj.org/article/6d0bb628e6f340e98058db8c16f208ca
Publikováno v:
Multiscale Imaging and Spectroscopy III.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5f86fe8c9b161d652adf5b8a65a12fb
https://doi.org/10.1117/12.2610110
https://doi.org/10.1117/12.2610110
Publikováno v:
Advanced Chemical Microscopy for Life Science and Translational Medicine 2022.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b49e67315158bf7b8d3c4acaf10b4b5b
https://doi.org/10.1117/12.2610133
https://doi.org/10.1117/12.2610133
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Skin is a heterogeneous tissue that can undergo substantial structural and functional changes with age, disease, or following injury. Understanding how these changes impact the mechanical properties of skin requires three-dimensional (3D) quantificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7172425b02e1429ce8c76067dd1919
http://europepmc.org/articles/PMC7966723
http://europepmc.org/articles/PMC7966723
Publikováno v:
Lasers Surg Med
Background and objectives Histological analysis is a gold standard technique for studying impaired skin wound healing. Label-free multiphoton microscopy (MPM) can provide natural image contrast similar to histological sections and quantitative metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d359cd723a497cc13c1ab11ee7ae8e17
https://europepmc.org/articles/PMC8275674/
https://europepmc.org/articles/PMC8275674/
Publikováno v:
Biophotonics Congress 2021.
Second harmonic generation microscopy was used to understand the micro-scale kinematic response of mouse skin under tensile loading. A substantial decrease in local tissue volume and non-affine 3D fiber kinematics were observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3041e7bd629ec4700a3a58590305b53c
https://doi.org/10.1364/ntm.2021.ntu3c.5
https://doi.org/10.1364/ntm.2021.ntu3c.5
Significance: Chronic wounds, such as diabetic foot ulcers, venous stasis ulcers, and pressure ulcers affect millions of Americans each year, and disproportionately afflict our increasingly older population. Older individuals are predisposed to wound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c69ffbe8cf4fda218a52911d16522e
https://europepmc.org/articles/PMC6985772/
https://europepmc.org/articles/PMC6985772/
Objective: The elderly are at high risk for developing chronic skin wounds, but the effects of intrinsic aging on skin healing are difficult to isolate due to common comorbidities like diabetes. Our objective is to use multiphoton microscopy (MPM) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c8df572f2d8469e20280c0392be393
https://europepmc.org/articles/PMC6985773/
https://europepmc.org/articles/PMC6985773/
Autor:
Kyle P. Quinn, Jake D. Jones
Publikováno v:
Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN).
Convolutional neural networks were used to accurately segment both H&E-stained tissue sections and in vivo autofluorescence images of skin wounds, which enabled automated, quantitative analysis of a variety of wound features.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e02a8f0e820638ba818331e14a2573
https://doi.org/10.1364/microscopy.2020.mm3a.2
https://doi.org/10.1364/microscopy.2020.mm3a.2
Autor:
Alexander Golberg, Jake D. Jones, Martin L. Yarmush, William G. Austin, Xiaoxiang Li, Nima Saeidi, Kyle P. Quinn, Martin Villiger, Hassan Albadawi
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 12:2309-2318
The demand for skin rejuvenation procedures has progressively increased in the past decade. Additionally, clinical trials have shown that current therapies might cause downtime and side effects in patients including prolonged erythema, scarring, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1fda3b7c35a3e2411f7e1321a5117a
https://doi.org/10.1002/term.2763
https://doi.org/10.1002/term.2763