Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jake Clayton"'
Autor:
Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://doaj.org/article/061b963a6e4f465eb098f328b26facdc
Autor:
Joanna Cheng, Christina Halsey, Matthew Bashton, Paul Sinclair, Shaun Hollern, Helen Marr, Peter Carey, Lars Buechler, Jake Clayton, Rebecca Hanna, Sarra Ryan, Helen J. Blair, Christine J. Harrison, Olaf Heidenreich, Zoe Hawking, Claire Schwab, Anthony V. Moorman, Lisa Jones, Lisa J. Russell
Publikováno v:
Haematologica
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d6a3be31ae824af1930e9517a6dab
https://eprints.gla.ac.uk/157726/13/157726.pdf
https://eprints.gla.ac.uk/157726/13/157726.pdf
Autor:
James, Grey, Dominic, Jones, Laura, Wilson, Sirintra, Nakjang, Jake, Clayton, Richard, Temperley, Emma, Clark, Luke, Gaughan, Craig, Robson
Publikováno v:
Oncotarget
The Androgen Receptor (AR) is a key molecule in the development, maintenance and progression of prostate cancer (PC). However, the relationship between the AR and co-regulatory proteins that facilitate AR activity in castrate resistant settings remai
Autor:
Haya H. Al-Balool, Pitsien Lang Ping Nam, Julie Irving, Jonathan Coxhead, Jake Clayton, Mark Wade, Kamlesh Guleria, Mauro Santibanez-Koref, Andrew G. Hall, David J. Elliott, Yilei Liu, Michael S. Jackson, Will P. M. Rowe, David Weber
Publikováno v:
Genome research
In silico analyses have established that transcripts from some genes can be processed into RNAs with rearranged exon order relative to genomic structure (post-transcriptional exon shuffling, or PTES). Although known to contribute to transcriptome div
Publikováno v:
Blood. 124:898-898
Deletions of the short arm of chromosome 12 (12p) are found in around 6% of acute myeloid leukaemia (AML). Particularly in paediatric AML they often occur as the sole cytogenetic change and impart a poor prognosis (Harrison et al J Clin Oncol 2010).
Autor:
Paul Sinclair, Lisa J. Russell, Jake Clayton, Lisa Jones, Lars Buechler, Joanna Cheng, Claire Schwab, Olaf Heidenreich, Bryan D. Young, Christine J. Harrison, Helen J. Blair
Publikováno v:
Blood. 122:2485-2485
Insight into the role of recurrent genomic changes arising in leukemia has depended largely on the functional analysis of cell lines and transgenic animals. However not all acquired abnormalities are represented in available cell lines and a few are