Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jake, Chen"'
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13975- (2023)
Objectives: To investigate the role of AdipoRon in bone wound healing of calvaria critical-sized defects (CSD) in diet-induced obesity (DIO) mice. Materials and methods: After establishing the calvaria CSD in normal-chow (NC), DIO and Adiponectin kno
Externí odkaz:
https://doaj.org/article/8237bb34a8a24c60813e15649a84a879
Autor:
Hongwen Yu, Hongle Wu, Qiuyan Xie, Zining Liu, Zehao Chen, Qisheng Tu, Jake Chen, Fuchun Fang, Wei Qiu
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundAdiponectin (APN) is an endogenous adipokine secreted from adipocytes that exerts anti-inflammatory properties. AdipoAI is an orally active adiponectin receptor agonist identified by our group that can emulate APN's anti-inflammatory proper
Externí odkaz:
https://doaj.org/article/2c5062fdc66746ceb4a0ce78ddb54fa6
Autor:
Hongle Wu, Wei Qiu, Xiaofang Zhu, Xiangfen Li, Zhongcong Xie, Isabel Carreras, Alpaslan Dedeoglu, Thomas Van Dyke, Yiping W. Han, Nadeem Karimbux, Qisheng Tu, Lei Cheng, Jake Chen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s Disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient’s quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In rece
Externí odkaz:
https://doaj.org/article/ad9c8b2201734b5b976017c5f363204a
Autor:
Zhekai Hu, Wei Qiu, Yuedi Yu, Xingwen Wu, Fuchun Fang, Xiaofang Zhu, Xiaoyang Xu, Qisheng Tu, Thomas E. Van Dyke, Elise F. Morgan, Jake Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
As a precursor to type 2 diabetes mellitus (T2D), obesity adversely alters bone cell functions, causing decreased bone quality. Currently, the mechanisms leading to alterations in bone quality in obesity and subsequently T2D are largely unclear. Emer
Externí odkaz:
https://doaj.org/article/b20fd3fda01348ec8447257a201829d6
Autor:
Syed Aun Muhammad, Hiba Ashfaq, Sidra Zafar, Fahad Munir, Muhammad Babar Jamshed, Jake Chen, Qiyu Zhang
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Type 2 diabetes mellitus (T2DM) is a worldwide disease that have an impact on individuals of all ages causing micro and macro vascular impairments due to hyperglycemic internal environment. For ultimate treatment to cure T2DM, ass
Externí odkaz:
https://doaj.org/article/468ec09618eb4000855bf99bcf7d316a
Autor:
Xiangfen Li, Xiaofang Zhu, Hongle Wu, Thomas E. Van Dyke, Xiaoyang Xu, Elise F. Morgan, Wenyu Fu, Chuanju Liu, Qisheng Tu, Dingming Huang, Jake Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1)
Externí odkaz:
https://doaj.org/article/f3df94293e9c44ffbc8bac428abd1658
Autor:
Wei Qiu, Zhaodan Wang, Zehao Chen, Qian Sun, Hongle Wu, Zhao Chen, Kaiqi Luan, Zining Liu, Dian Ding, Qisheng Tu, Jake Chen, Buling Wu, Fuchun Fang
Publikováno v:
British Journal of Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57aeb8bbcefd0d57c64c4dabe541213a
https://doi.org/10.1111/bph.16103
https://doi.org/10.1111/bph.16103
Autor:
Huimin Xu, Chitrank Gupta, Zhandos Sembay, Swathi Thaker, Pamela Payne-Foster, Jake Chen, Ying Ding
Publikováno v:
Companion Proceedings of the ACM Web Conference 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd955c58f8af2d698ce9cfed251d382
https://doi.org/10.1145/3543873.3587579
https://doi.org/10.1145/3543873.3587579
Autor:
Wei Qiu, Zehao Chen, Zhaodan Wang, Yuanting Chen, Kaiqi Luan, Kaiying Zhang, Hongwen Yu, Qisheng Tu, Jake Chen, Hongle Wu, Fuchun Fang
Publikováno v:
Clinical Oral Implants Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5efb9aa32a315659750b438356fda960
https://doi.org/10.1111/clr.14070
https://doi.org/10.1111/clr.14070
Publikováno v:
Proceedings of the 28th ACM SIGKDD Conference on Knowledge Discovery and Data Mining.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::636a5b04e15da3ca0014e5a3a84de3d7
https://doi.org/10.1145/3534678.3542888
https://doi.org/10.1145/3534678.3542888