Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jaiyanth Daniel"'
Autor:
Timilehin Faboro, Jaiyanth Daniel
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0311669 (2024)
Mycobacterium abscessus is a biofilm-forming, non-tuberculous mycobacterium that is highly resistant to antibiotics. Bacterial efflux pumps contribute to biofilm formation, export of biofilm-associated lipids and antibiotic tolerance. The Resistance
Externí odkaz:
https://doaj.org/article/7cfa56e4dcc34cd38bc9264ed0a556be
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114877 (2014)
Latent infection with dormant Mycobacterium tuberculosis is one of the major reasons behind the emergence of drug-resistant strains of the pathogen worldwide. In its dormant state, the pathogen accumulates lipid droplets containing triacylglycerol sy
Externí odkaz:
https://doaj.org/article/977e46a29ff548f9ad4fbf034584c870
Autor:
Dheeraj Verma, Shuangxia Jin, Anderson Kanagaraj, Nameirakpam D Singh, Jaiyanth Daniel, Pappachan E Kolattukudy, Michael Miller, Henry Daniell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57187 (2013)
In order to produce low-cost biomass hydrolyzing enzymes, transplastomic lines were generated that expressed cutinase or swollenin within chloroplasts. While swollenin expressing plants were homoplasmic, cutinase transplastomic lines remained heterop
Externí odkaz:
https://doaj.org/article/1845e59fa40347898943fd9f3563a06a
Autor:
Tatiana D Sirakova, Chirajyoti Deb, Jaiyanth Daniel, Harminder D Singh, Hedia Maamar, Vinod S Dubey, Pappachan E Kolattukudy
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51641 (2012)
Mycobacterium tuberculosis (Mtb) is known to produce wax esters (WE) when subjected to stress. However, nothing is known about the enzymes involved in biosynthesis of WE and their role in mycobacterial dormancy. We report that two putative Mtb fatty
Externí odkaz:
https://doaj.org/article/1b159b0d90014439beae394c46d77a4b
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002093 (2011)
Two billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb-infected macrophages are likely to be sequestered inside the hypoxic environments of the granuloma and differentiate into lipid-loaded macrophages that contain triacy
Externí odkaz:
https://doaj.org/article/5060ff77689344c88b673aa65771967b
Autor:
Chirajyoti Deb, Chang-Muk Lee, Vinod S Dubey, Jaiyanth Daniel, Bassam Abomoelak, Tatiana D Sirakova, Santosh Pawar, Linda Rogers, Pappachan E Kolattukudy
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6077 (2009)
BACKGROUND:Mycobacterium tuberculosis (Mtb) becomes dormant and phenotypically drug resistant when it encounters multiple stresses within the host. Inability of currently available drugs to kill latent Mtb is a major impediment to curing and possibly
Externí odkaz:
https://doaj.org/article/9f4c73837da34623ac4e73aad3774336
Autor:
Sushanta Ratna, Jaiyanth Daniel
Publikováno v:
Microbial Pathogenesis. 174:105943
Nontuberculous mycobacteria (NTM) such as Mycobacterium smegmatis accumulate high levels of glycopeptidolipids (GPLs) on their outer surface. The biosynthesis of GPLs is critically linked to biofilm formation by NTM which also includes opportunistic
Autor:
Audrey Martin, Jaiyanth Daniel
Publikováno v:
Biochemical and Biophysical Research Communications. 496:667-672
Mycobacterium tuberculosis (Mtb), which causes tuberculosis, is capable of accumulating triacylglycerol (TAG) by utilizing fatty acids from host cells. ATP-binding cassette (ABC) transporters are involved in transport processes in all organisms. Amon
Publikováno v:
Biochemical and Biophysical Research Communications. 495:35-40
The Rv2477c protein of Mycobacterium tuberculosis (Mtb) belongs to the ATP-binding cassette (ABC) subfamily F that contains proteins with tandem nucleotide-binding domains but lacking transmembrane domains. ABC-F subfamily proteins have been implicat
Publikováno v:
Molecular Microbiology. 101:784-794
Mycobacterium tuberculosis (Mtb) causes latent tuberculosis infection in one-third of the world population and remains quiescent in the human body for decades. The dormant pathogen accumulates lipid droplets containing triacylglycerol (TAG). In mamma