Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jaiwoo, Lee"'
Autor:
Quoc‐Viet Le, Jaiwoo Lee, Seungbeom Ko, Hyunjung Kim, Thien Y Vu, Yearn Seong Choe, Yu‐Kyoung Oh, Gayong Shim
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 5, Pp n/a-n/a (2023)
Abstract Metal chelator‐based contrast agents are used as tumor navigators for cancer diagnosis. Although approved metal chelators show excellent contrast performance in magnetic resonance imaging (MRI), large doses are required for cancer diagnose
Externí odkaz:
https://doaj.org/article/65417bd4c5484ccfb4160140b4021920
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 160-172 (2022)
In immunotherapy, ex vivo stimulation of T cells requires significant resources and effort. Here, we report artificial dendritic cell-mimicking DNA microflowers (DM) for programming T cell stimulation in situ. To mimic dendritic cells, DNA-based arti
Externí odkaz:
https://doaj.org/article/d57d76aaaadc4a6bb78eb6844a063f30
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Activated hepatic stellate cells contribute towards the pathogenesis of liver fibrosis, and overexpress fibroblast activation protein. Here the authors report a targeted peptide-delivery system in which fibroblast activation protein liberates the ant
Externí odkaz:
https://doaj.org/article/5dda064f6ea54360a99c3fb981fd83fb
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2096-2113 (2021)
Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesi
Externí odkaz:
https://doaj.org/article/4ddc86f46cc84abc91e530a177127021
Autor:
Ling-Feng Zhang, Xing-Huan Wang, Cheng-Lu Zhang, Jaiwoo Lee, Bo-Wen Duan, Lei Xing, Ling Li, Yu-Kyoung Oh, Hu-Lin Jiang
Publikováno v:
ACS Nano. 16:14029-14042
During liver fibrogenesis, liver sinusoidal capillarization and extracellular matrix (ECM) deposition construct dual pathological barriers to drug delivery. Upon capillarization, the vanished fenestrae in liver sinusoidal endothelial cells (LSECs) si
Autor:
Quoc‐Viet Le, Jaiwoo Lee, Seungbeom Ko, Hyunjung Kim, Thien Y Vu, Yearn Seong Choe, Yu‐Kyoung Oh, Gayong Shim
Publikováno v:
Bioengineering & Translational Medicine.
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 35(1)
Herein, a tolerogenic nanovaccine is developed and tested on an animal model of multiple sclerosis. The nanovaccine is constructed to deliver the self-antigen, myelin oligodendrocyte glycoprotein (MOG) peptide, and dexamethasone on an abatacept-modif
Autor:
Jinwon, Park, Yina, Wu, Qiaoyun, Li, Jaehyun, Choi, Hyemin, Ju, Yu, Cai, Jaiwoo, Lee, Yu-Kyoung, Oh
Publikováno v:
Drug Delivery and Translational Research.
Impairment of immune tolerance might cause autologous tissue damage or overactive immune response against non-pathogenic molecules. Although autoimmune disease and allergy have complicated pathologies, the current strategies have mainly focused on sy
Publikováno v:
Biomaterials. 299:122162
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2096-2113 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2096-2113 (2021)
Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesi