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Autor:
Hak-Zoo Kim, Jais Kavumkal, Gou Young Koh, Harprit Singh, Nicholas P.J. Brindle, Marie B. Marron, Tariq A. Tahir
Publikováno v:
Journal of Biological Chemistry. 282:30509-30517
Regulated ectodomain shedding followed by intramembrane proteolysis has recently been recognized as important in cell signaling and for degradation of several type I transmembrane proteins. The receptor-tyrosine kinase Tie1 is known to undergo ectodo