Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jairus M. Reddy"'
Publikováno v:
Molecular Neurobiology. 57:2220-2231
Mevalonate pathway inhibitors have been extensively studied for their roles in cholesterol depletion and for inhibiting the prenylation and activation of various proteins. Inhibition of protein prenylation has potential therapeutic uses against neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7a0413c2a0f6afe54827b28afc8b08
https://doi.org/10.1007/s12035-020-01870-0
https://doi.org/10.1007/s12035-020-01870-0
Publikováno v:
Molecular neurobiology. 57(5)
Mevalonate pathway inhibitors have been extensively studied for their roles in cholesterol depletion and for inhibiting the prenylation and activation of various proteins. Inhibition of protein prenylation has potential therapeutic uses against neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::486287b249f1340c168a9daf94d4b089
https://pubmed.ncbi.nlm.nih.gov/31989383
https://pubmed.ncbi.nlm.nih.gov/31989383
Autor:
Jordan A. McConnell, Jairus M. Reddy, Brian W. Beck, Cristina P. Reddy, DiAnna L. Hynds, Filsy Samuel
Publikováno v:
Cellular Signalling. 27:630-637
Rac1 is an important regulator of axon extension, cell migration and actin reorganization. Like all Rho guanine triphosphatases (GTPases), Rac1 is targeted to the membrane by the addition of a geranylgeranyl moiety, an action thought to result in Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304d30f642cda1684862e85135cb80c1
https://doi.org/10.1016/j.cellsig.2014.11.033
https://doi.org/10.1016/j.cellsig.2014.11.033
Publikováno v:
Journal of Public Mental Health. 10:45-56
PurposeThe purpose of this paper is to obtain perceptions of educated non‐professionals towards people with schizophrenia.Design/methodology/approachA social distance scale and a schizophrenia knowledge and attitude survey were administered to 330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d0805e6e4b8c9145ca4dc102bd9862
https://doi.org/10.1108/17465721111134547
https://doi.org/10.1108/17465721111134547
Publikováno v:
Molecular neurobiology. 50(1)
Inhibitors of the mevalonate pathway, including the highly prescribed statins, reduce the production of cholesterol and isoprenoids such as geranylgeranyl pyrophosphates. The Rho family of small guanine triphosphatases (GTPases) requires isoprenylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b48be37dddee8a7bb64bfabeb239c88
https://pubmed.ncbi.nlm.nih.gov/24515839
https://pubmed.ncbi.nlm.nih.gov/24515839