Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jairo R Temerozo"'
Autor:
Suelen Silva Gomes Dias, Vinicius Cardoso Soares, André C Ferreira, Carolina Q Sacramento, Natalia Fintelman-Rodrigues, Jairo R Temerozo, Lívia Teixeira, Marcos Alexandre Nunes da Silva, Ester Barreto, Mayara Mattos, Caroline S de Freitas, Isaclaudia G Azevedo-Quintanilha, Pedro Paulo A Manso, Milene D Miranda, Marilda Mendonça Siqueira, Eugenio D Hottz, Camila R R Pão, Dumith C Bou-Habib, Debora F Barreto-Vieira, Fernando A Bozza, Thiago M L Souza, Patricia T Bozza
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009127 (2020)
Viruses are obligate intracellular parasites that make use of the host metabolic machineries to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus replication may lead to potential targets for therapeutic inter
Externí odkaz:
https://doaj.org/article/efc5a0370f864f88af78a38a55522ac3
Autor:
Aline D. Purificação, Sabrina Silva-Mendonça, Luiza V. Cruz, Carolina Q. Sacramento, Jairo R. Temerozo, Natalia Fintelman-Rodrigues, Caroline Souza de Freitas, Bruna Fleck Godoi, Miguel Menezes Vaidergorn, Juliana Almeida Leite, Luis Carlos Salazar Alvarez, Murillo V. Freitas, Meryck F. B. Silvac, Bianca A. Martin, Renata F. V. Lopez, Bruno J. Neves, Fabio T. M. Costa, Thiago M. L. Souza, Flavio da Silva Emery, Carolina Horta Andrade, M. Cristina Nonato
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11418-11430 (2024)
Externí odkaz:
https://doaj.org/article/39a3e0cbd8ee4c37b266127366a305cb
Autor:
Milene Mesquita, Natalia Fintelman-Rodrigues, Carolina Q Sacramento, Juliana L Abrantes, Eduardo Costa, Jairo R Temerozo, Marilda M Siqueira, Dumith Chequer Bou-Habib, Thiago Moreno L Souza
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101056 (2014)
HIV-1-infected patients co-infected with A(H1N1)pdm09 surprisingly presented benign clinical outcome. The knowledge that HIV-1 changes the host homeostatic equilibrium, which may favor the patient resistance to some co-pathogens, prompted us to inves
Externí odkaz:
https://doaj.org/article/3707e4fbfc6a4275b51de58a6b6c81fb
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67701 (2013)
It is well established that host factors can modulate HIV-1 replication in macrophages, critical cells in the pathogenesis of HIV-1 infection due to their ability to continuously produce virus. The neuropeptides VIP and PACAP induce well-characterize
Externí odkaz:
https://doaj.org/article/3bd58c0aa5074c72be30c8f35d505337
Autor:
Guilherme C. Lechuga, Jairo R. Temerozo, Paloma Napoleão-Pêgo, João P. R. S. Carvalho, Larissa R. Gomes, Dumith Chequer Bou-Habib, Carlos M. Morel, David W. Provance, Thiago M. L. Souza, Salvatore G. De-Simone
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8180 (2024)
Despite successful vaccination efforts, the emergence of new SARS-CoV-2 variants poses ongoing challenges to control COVID-19. Understanding humoral responses regarding SARS-CoV-2 infections and their impact is crucial for developing future vaccines
Externí odkaz:
https://doaj.org/article/d6b8088a6c6a4050b3bba2afb0bcfb93
Autor:
Fernando Augusto T. P. Meireles, Deborah Antunes, Jairo R. Temerozo, Dumith Chequer Bou-Habib, Ernesto Raul Caffarena
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-17
The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) belongs to the glucagon/secretin family. PACAP interacts with the pituitary adenylate cyclase-activating polypeptide receptor type 1 (PAC1) and vasoactive intestinal peptide
Autor:
Otávio Augusto Chaves, Carlyle Ribeiro Lima, Natalia Fintelman-Rodrigues, Carolina Q. Sacramento, Caroline S. de Freitas, Leonardo Vazquez, Jairo R. Temerozo, Marco E.N. Rocha, Suelen S.G. Dias, Nicolas Carels, Patrícia T. Bozza, Hugo Caire Castro-Faria-Neto, Thiago Moreno L. Souza
Publikováno v:
International Journal of Biological Macromolecules. 222:1015-1026
Despite the fast development of vaccines, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still circulates through variants of concern (VoC) and escape the humoral immune response. SARS-CoV-2 has provoked over 200,000 deaths/months s
Autor:
Eugenio D. Hottz, Remy Martins-Gonçalves, Lohanna Palhinha, Isaclaudia G. Azevedo-Quintanilha, Mariana M. de Campos, Carolina Q. Sacramento, Jairo R. Temerozo, Vinicius Cardoso Soares, Suelen S. Gomes Dias, Lívia Teixeira, Ícaro Castro, Cassia Righy, Thiago Moreno L. Souza, Pedro Kurtz, Bruno B. Andrade, Helder I. Nakaya, Robson Q. Monteiro, Fernando A. Bozza, Patrícia T. Bozza
Publikováno v:
Blood Advances. 6:5085-5099
Accumulating evidence into the pathogenesis of COVID-19 highlights a hypercoagulability state with high risk of life-threatening thromboembolic complications. However, the mechanisms of hypercoagulability and their link to hyperinflammation remain po
Autor:
Ana C. Puhl, Melina Mottin, Carolina Q. Sacramento, Tatyana Almeida Tavella, Gabriel Gonçalves Dias, Natalia Fintelman-Rodrigues, Jairo R. Temerozo, Suelen S. G. Dias, Paulo Ricardo Pimenta da Silva Ramos, Eric M. Merten, Kenneth H. Pearce, Fabio Trindade Maranhão Costa, Lakshmanane Premkumar, Thiago Moreno L. Souza, Carolina Horta Andrade, Sean Ekins
Publikováno v:
ACS Omega. 7:27950-27958
Finding antivirals for SARS-CoV-2 is still a major challenge, and many computational and experimental approaches have been employed to find a solution to this problem. While the global vaccination campaigns are the primary driver of controlling the c
Autor:
Ronaldo da Silva Francisco Junior, Jairo R. Temerozo, Cristina dos Santos Ferreira, Yasmmin Martins, Thiago Moreno L. Souza, Enrique Medina-Acosta, Ana Tereza Ribeiro de Vasconcelos
Publikováno v:
Frontiers in Immunology. 13
IntroductionCell entry of SARS-CoV-2 causes genome-wide disruption of the transcriptional profiles of genes and biological pathways involved in the pathogenesis of COVID-19. Expression allelic imbalance is characterized by a deviation from the Mendel