Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jairo Perez Sanz"'
Autor:
Subir Biswas, Tara Lee Costich, Jairo Perez-Sanz, Kimberly B. Sprenger, Jose R. Conejo-Garcia, Paulo C. Rodriguez, Xiaoqing Yu, Gunjan Mandal, Lubomir Sokol, Kristen E. Rigolizzo, Kebin Liu, Jessica A. Mine, Javier Pinilla-Ibarz, Ricardo A. Chaurio, Kyle K. Payne, Carmen M. Anadon, Louise C. Showe, Carly M. Harro
Publikováno v:
J Clin Invest
Cutaneous T cell lymphoma (CTCL) has a poorly understood etiology and no known cure. Using conditional knockout mice, we found that ablation of the genomic organizer special AT-rich sequence–binding protein 1 (Satb1) caused malignant transformation
Autor:
Ricardo A. Chaurio, Jairo Perez-Sanz, Kyle K. Payne, Alfredo Perales-Puchalt, Hengrui Zhu, Mark E. Borowsky, Rugang Zhang, Terri M. Laufer, Tom L. Stephen, Ana E. Vara-Ailor, Evgeniy Eruslanov, Jose R. Conejo-Garcia, Michael J. Allegrezza, Jenny M. Nguyen
Publikováno v:
Immunity. 46:51-64
Despite the importance of programmed cell death-1 (PD-1) in inhibiting T cell effector activity, the mechanisms regulating its expression remain poorly defined. We found that the chromatin organizer special AT-rich sequence-binding protein-1 (Satb1)
Autor:
Carly Harro, Jairo Perez-Sanz, Tara Lee Costich, Kyle K Payne, Carmen Maria Anadon Galindo, Ricardo A Chaurio Gonzalez, Subir Biswas, Gunjan Mandal, Kristen E Rigolizzo, Jessica A Mine, Louise C Showe, Kebin Liu, Paulo C Rodriguez, Javier Lee Pinilla-Ibarz, Lubomir Sokol, Jose R Conejo-Garcia
Publikováno v:
The Journal of Immunology. 204:154.8-154.8
Cutaneous T cell lymphoma (CTCL) is a clinically unmet need. Using conditional knockout mice, we found that ablation of the genomic organizer Special AT rich sequence binding protein 1 (Satb1) induces a progressively fatal lymphoma characterized by m
Autor:
Carmen Maria Anadon Galindo, Xiaoqing Yu, Ricardo A Chaurio Gonzalez, Kyle K Payne, Subir Biswas, Tara Lee Costich, Jairo Perez-Sanz, Gunjan Mandal, Alexandra L Martin, Carly Harro, Chase Powell, Jessica A Mine, Zhitao Wang, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 204:89.3-89.3
The relationship between stem-like, tissue resident memory (TRM) and exhausted T cells at tumor beds is incompletely understood. We found that more than 50% of the CD8+ T cells in human ovarian carcinomas are TRM cells. RNA seq of TRM and their re-ci
Autor:
Nikolaos Svoronos, Michael J. Allegrezza, Kyle K. Payne, Jessica A. Mine, Alfredo Perales-Puchalt, Subir Biswas, Tara Lee Costich, Logan M. Nickels, Melanie R. Rutkowski, Ricardo A. Chaurio, Jairo Perez-Sanz, Jayamanna Wickramasinghe, Carmen M. Anadon, Joseph Calmette, Jose R. Conejo-Garcia
Publikováno v:
Journal of leukocyte biology. 103(5)
Due to their cytotoxic activities, many anticancer drugs cause extensive damage to the intestinal mucosa and have antibiotic activities. Here, we show that cisplatin induces significant changes in the repertoire of intestinal commensal bacteria that
Autor:
Kyle K Payne, Ricardo Chaurio Gonzalez, Jairo Perez Sanz, Carmen Maria Anadon Galindo, Subir Biswas, Jessica A Mine, Alfredo Perales-Puchalt, Evgenii Tsiganov, Tara Lee Costich, Carly M Harro, Aubrey K Marrs, Jason Lajoie, Kun-Po Li, Michael Ophir, Ugur Eskiocak, Michael Schmidt, Dmitry I Gabrilovich, Jose R Conejo-Garcia
Publikováno v:
The Journal of Immunology. 202:194.2-194.2
Ovarian carcinoma microenvironmental T cells exert clinically relevant pressure against malignant progression; however current immunotherapies rarely induce ovarian cancer regression. Here we investigate CD277-containing butyrophilin 3A1 (BTN3A1), a
Autor:
Ricardo A Chaurio Gonzalez, Subir Biswas, Kyle K. Payne, Carmen Maria Anadon Galindo, Tara Lee Costich, Alfredo Perales-Puchalt, Jairo Perez-Sanz, Carly M Harro, Jessica A Mine, Michael J Allegrezza, Nikolaos Svoronos, Jodi Kroeger, John Robinson, Jose R Conejo-Garcia
Publikováno v:
The Journal of Immunology. 202:138.22-138.22
T Follicular Helper cells (TFH) provide both co-stimulation and stimulatory cytokines to B cells to facilitate affinity maturation, class switch recombination, and plasma cell differentiation within the germinal center. However, is not clear how TFH
Autor:
Carmen Maria Anadon Galindo, Jairo Perez Sanz, Subir Biswas, Kyle K. Payne, Xiaoqing Yu, Tara Lee Costich, Ricardo Chaurio Gonzalez, Jose R Conejo-Garcia
Publikováno v:
The Journal of Immunology. 202:138.4-138.4
Conventional memory T cells classically include central memory T (TCM) cells, residing in lymphoid organs, and effector memory T (TEM) cells, circulating through various tissues. Recently, a novel population of memory T cells has gained interest, nam
Autor:
Kyle K. Payne, Nikolaos Svoronos, Ricardo A. Chaurio, Jairo Perez Sanz, Carmen Anadon, Joseph Calmette, Subir Biswas, Tara Lee Costich, Jessica Mine, Jose R. Conejo-Garcia
Publikováno v:
The Journal of Immunology. 200:178.15-178.15
Despite the emergence of immunotherapy for the treatment of cancer, many of the fundamental mechanisms which characterize tumors that are amenable to immunotherapy and/or drive superior endogenous anti-tumor immune responses likely remain uncharacter
Autor:
Kyle K Payne, Tom L Stephen, Ricardo A Chaurio, Michael J Allegrezza, Hengrui Zhu, Jairo Perez-Sanz, Alfredo Perales-Puchalt, Jenny M Nguyen, Ana Vara-Ailor, Evgeniy B Eruslanov, Mark E Borowsky, Rugang Zhang, Terri M Laufer, Jose R Conejo-Garcia
Publikováno v:
The Journal of Immunology. 198:56.8-56.8
Despite the importance of Programmed Cell Death-1 (PDCD1/PD-1) in inhibiting T-cell effector activity, the mechanisms regulating its expression in anti-tumor lymphocytes remain poorly defined. Here we show that the chromatin organizer Special AT-rich