Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jairaj Mathur"'
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112362- (2023)
Summary: Adherent cells migrate on layered tissue interfaces to drive morphogenesis, wound healing, and tumor invasion. Although stiffer surfaces are known to enhance cell migration, it remains unclear whether cells sense basal stiff environments bur
Externí odkaz:
https://doaj.org/article/ab40cd5d5abd4adf98374af9bdc2f944
Publikováno v:
Molecular Biology of the Cell. 34
Cell invasion across mechanically dissimilar environments is mediated by cell-to-matrix transfer of mechanical memory. Past mechanical priming of cells in stiff environments increases cellular forces that enhance collagen remodeling and subsequent ce
Autor:
Priscilla Y Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Daphne Cornish, Maria Clarke, Amit Pathak, Gregory D Longmore
Carcinoma dissemination can occur when heterogeneous tumor and tumor stromal cells clusters migrate together via collective migration. Cells at the front lead and direct collective migration, yet how these leader cells form and interact with the micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10748bf22d266181703c9fe4db459954
https://doi.org/10.1101/2022.05.10.491382
https://doi.org/10.1101/2022.05.10.491382
In disease and development, cells sense and migrate across mechanically dissimilar environments. We investigated whether mechanical memory of past environments empowers cells to navigate new, three-dimensional environments. Here, we show that cells p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d934bd15a65ca1bec1330f5acc256ded
https://doi.org/10.1101/2022.05.02.490316
https://doi.org/10.1101/2022.05.02.490316
Cellular forces and intercellular cooperation generate collective cell migration. Pathological changes in cell-level genetic and physical properties cause jamming, unjamming, and scattering in epithelial migration. Separately, changes in microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b471d47f86e351badf3f2a83c5ddfaa2
https://doi.org/10.1101/2022.04.28.489943
https://doi.org/10.1101/2022.04.28.489943
Autor:
Priscilla Y. Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Jiayu Ye, Vasilios Morikis, Daphne Cornish, Maria Clarke, Sheila A. Stewart, Amit Pathak, Gregory D. Longmore
Publikováno v:
Developmental Cell. 58:34-50.e9
Publikováno v:
Biophys J
Mechanotransduction describes activation of gene expression by changes in the cell’s physical microenvironment. Recent experiments show that mechanotransduction can lead to long-term “mechanical memory,” in which cells cultured on stiff substra
Mechanotransduction describes activation of gene expression by changes in the cell’s physical microenvironment. Recent experiments show that mechanotransduction can lead to long-term “mechanical memory”, where cells cultured on stiff substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1501c11c15c5e4d1d04ac34bc9804f18
https://doi.org/10.1101/2021.06.23.449595
https://doi.org/10.1101/2021.06.23.449595
Publikováno v:
Biophysical Journal. 115:2474-2485
Collective migration of heterogeneous cell populations is an essential aspect of fundamental biological processes, including morphogenesis, wound healing, and tumor invasion. Through experiments and modeling, it has been shown that cells attain front
Autor:
Priscilla Y. Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Daphne Cornish, Maria Clarke, Amit Pathak, Gregory Longmore
Publikováno v:
SSRN Electronic Journal.