Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jair R. Chagas"'
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Human tissue Kallikrein-related peptidases (hKLKs) are serine proteases distributed in several tissues that are involved in several biological processes. In skin, many are responsible for skin desquamation in the Stratum Corneum (SC) of the epidermis
Externí odkaz:
https://doaj.org/article/e7855844b22045d58945edbf0ac866d2
Autor:
Bruna Visniauskas, Juliana C. Perry, Guiomar N. Gomes, Amanda Nogueira‐Pedro, Edgar J. Paredes‐Gamero, Sergio Tufik, Jair R. Chagas
Publikováno v:
Physiological Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Abstract Intermittent hypoxia (IH) is a feature of obstructive sleep apnea (OSA), a condition highly associated with hypertension‐related cardiovascular diseases. Repeated episodes of IH contribute to imbalance of angiogenic growth factors in the h
Externí odkaz:
https://doaj.org/article/ea12f9170490432cb4977bcc80fbe94c
Autor:
Bruna Visniauskas, Priscila S.R. Simões, Fernanda M. Dalio, Maria D.G. Naffah-Mazzacoratti, Vitor Oliveira, Sergio Tufik, Jair R. Chagas
Publikováno v:
Heliyon, Vol 5, Iss 11, Pp e02896- (2019)
The consequences of sleep deprivation on memory, cognition, nociception, stress, and endocrine function are related to the balance of neuropeptides, with peptidases being particularly essential. Thimet oligopeptidase (THOP1) is a metallopeptidase imp
Externí odkaz:
https://doaj.org/article/6c0d9236ce694fcb90e67e6f9ccc300c
Autor:
Nilton B. dos Santos, Roseane D. Franco, Rosana Camarini, Carolina D. Munhoz, Rosangela A. S. Eichler, Mayara C. F. Gewehr, Patricia Reckziegel, Ricardo P. Llanos, Camila S. Dale, Victoria R. O. da Silva, Vanessa F. Borges, Braulio H. F. Lima, Fernando Q. Cunha, Bruna Visniauskas, Jair R. Chagas, Sergio Tufik, Fernanda F. Peres, Vanessa C. Abilio, Jorge C. Florio, Leo K. Iwai, Vanessa Rioli, Benedito C. Presoto, Alessander O. Guimaraes, Joao B. Pesquero, Michael Bader, Leandro M. Castro, Emer S. Ferro
Publikováno v:
Biomolecules, Vol 9, Iss 8, p 382 (2019)
Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1−/−) is described showing that they are viable, h
Externí odkaz:
https://doaj.org/article/fee5d888dd5846aa93227678225a6f5a
Publikováno v:
Headache Medicine. 11:14-21
Angiotensin converting enzyme-1 (ACE) has been implicated in sleep regulation and nociception. In a secondary, per-protocol analysis, we investigated the effect of a 12-week aerobic exercise program on plasma ACE activity (primary outcome variable),
Autor:
Suzan Pantaroto de Vasconcellos, Marghuel A. Vieira Silveira, Jair R. Chagas, Saara M. B. Santos, Maria A. Juliano, Itamar Soares de Melo, Debora Noma Okamoto
Publikováno v:
Environmental technology.
Actinomycetes are versatile about their metabolism, displaying high capacity to produce bioactive metabolites. Enzymes from actinomycetes represent new opportunities for industrial applications. However, proteases from actinomycetes are poorly descri
Publikováno v:
The primary care companion for CNS disorders. 23(5)
Publikováno v:
Frontiers in medicine. 8
Human tissue Kallikrein-related peptidases (hKLKs) are serine proteases distributed in several tissues that are involved in several biological processes. In skin, many are responsible for skin desquamation in the Stratum Corneum (SC) of the epidermis
Autor:
Rafael Filippelli da Silva, Paola Bianchi Guimarães, Clovis R. Nakaie, João Bosco Pesquero, Jair R. Chagas, Liliam Fernandes, Adriana K. Carmona, Michael Bader, Carolina Caldas Hoff
Publikováno v:
Inflammation Research. 68:845-855
Carboxypeptidase M (CPM) is a glycosylphosphatidylinositol anchored enzyme that plays an important role in the kallikrein–kinin system (KKS). CPM catalytic domain hydrolyzes Arg from C-terminal peptides (i.e., bradykinin and kallidin), generating d
Autor:
Celina Tizuko Fujiyama Oshima, Dalva Poyares, Orlando Ambrogini-Junior, Paula Midori Castelo, Deise Luna Paixão, Jair R. Chagas, Marta Sevilha de Paula, Ana Paula Ribeiro Paiotti, Sender Jankiel Miszputen, Joselmo Willamys Duarte
Publikováno v:
Journal of Clinical Sleep Medicine. 15:39-45
STUDY OBJECTIVES: The pathogenesis of inflammatory bowel disease (IBD) is not well understood, and sleep disorders may be potential triggers for IBD. Thus, an evaluation of the sleep characteristics, fatigue symptoms, and cytokine levels was performe