Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jaione Simón-Santamaria"'
Autor:
Milton Boaheng Antwi, Gianina Dumitriu, Jaione Simón-Santamaria, Javier Sánchez Romano, Ruomei Li, Bård Smedsrød, Anders Vik, Winnie Eskild, Karen Kristine Sørensen
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/c51a26ac638f4418b6bee99e17e4ed4a
Autor:
Milton Boaheng Antwi, Gianina Dumitriu, Jaione Simón-Santamaria, Javier Sánchez Romano, Ruomei Li, Bård Smedsrød, Anders Vik, Winnie Eskild, Karen Kristine Sørensen
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293526 (2023)
Liver sinusoidal endothelial cells (LSECs) are fenestrated endothelial cells with a unique, high endocytic clearance capacity for blood-borne waste macromolecules and colloids. This LSEC scavenger function has been insufficiently characterized in liv
Externí odkaz:
https://doaj.org/article/a4bd4f03d10a49dd91af39baab313b54
Autor:
Sabin Bhandari, Ingelin Kyrrestad, Jaione Simón-Santamaría, Ruomei Li, Karolina Joanna Szafranska, Gianina Dumitriu, Javier Sánchez Romano, Bård Smedsrød, Karen Kristine Sørensen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Liver sinusoidal endothelial cells (LSECs) which make up the fenestrated wall of the hepatic sinusoids, are active scavenger cells involved in blood waste clearance and liver immune functions. Dexamethasone is a synthetic glucocorticoid commonly used
Externí odkaz:
https://doaj.org/article/ab75d3afdc8f40b7aff9ae5b89cda46b
Autor:
Christopher Holte, Karolina Szafranska, Larissa Kruse, Jaione Simon-Santamaria, Ruomei Li, Dmitri Svistounov, Peter McCourt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Oxidized albumin (oxHSA) is elevated in several pathological conditions, such as decompensated cirrhosis, acute on chronic liver failure and liver mediated renal failure. Patient derived oxidized albumin was previously shown to be an inflamm
Externí odkaz:
https://doaj.org/article/43bab7e1580846c4b433f7be9e547572
Autor:
Javier Sánchez Romano, Jaione Simón-Santamaría, Peter McCourt, Bård Smedsrød, Kim Erlend Mortensen, Antonia P. Sagona, Karen Kristine Sørensen, Anett Kristin Larsen
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTPhage treatment has regained attention due to an increase in multiresistant bacteria. For phage therapy to be successful, phages must reach their target bacteria in sufficiently high numbers. Blood-borne phages are believed to be captured by
Externí odkaz:
https://doaj.org/article/322761b930ff4aa483fc0a61ede23986
Autor:
Ingelin Kyrrestad, Anett Kristin Larsen, Javier Sánchez Romano, Jaione Simón-Santamaría, Ruomei Li, Karen Kristine Sørensen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Liver sinusoidal endothelial cells (LSEC) are scavenger cells with a remarkably high capacity for clearance of several blood-borne macromolecules and nanoparticles, including some viruses. Endocytosis in LSEC is mainly via the clathrin-coated pit med
Externí odkaz:
https://doaj.org/article/d741acad182044d5a566378b2144f8b6
Autor:
Sabin Bhandari, Ruomei Li, Jaione Simón-Santamaría, Peter McCourt, Steinar Daae Johansen, Bård Smedsrød, Inigo Martinez-Zubiaurre, Karen Kristine Sørensen
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-25 (2020)
Abstract Background Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs; liver resident macrophages) form the body’s most effective scavenger cell system for the removal of harmful blood-borne substances, ranging from modified self-pr
Externí odkaz:
https://doaj.org/article/d13202d6a8f942aba4866dc380ee249b
Autor:
Ruomei Li, Sabin Bhandari, Inigo Martinez-Zubiaurre, Jack-Ansgar Bruun, Ilona Urbarova, Bård Smedsrød, Jaione Simón-Santamaría, Karen Kristine Sørensen
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273843 (2022)
IntroductionLiver sinusoidal endothelial cells (LSECs) are specialized fenestrated scavenger endothelial cells involved in the elimination of modified plasma proteins and tissue turnover waste macromolecules from blood. LSECs also participate in live
Externí odkaz:
https://doaj.org/article/4d0faf067e154d509f58231c3c97dfca
Autor:
Anett Kristin Larsen, Jaione Simón-Santamaría, Kjetil Elvevold, Bo Göran Ericzon, Kim Erlend Mortensen, Peter McCourt, Bård Smedsrød, Karen Kristine Sørensen
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss 4 (2021)
Autofluorescent granules of various sizes were observed in primary human liver endothelial cells (LSECs) upon laser irradiation using a wide range of wavelengths. Autofluorescence was detected in LAMP-1 positive vesicles, suggesting lysosomal locatio
Externí odkaz:
https://doaj.org/article/3f7d7211341a433daf08507dbcaf4dd7
Autor:
Jaione Simon-Santamaria, Christine Hanssen Rinaldo, Piotr Kardas, Ruomei Li, Ivana Malovic, Kjetil Elvevold, Peter McCourt, Bård Smedsrød, Hans H Hirsch, Karen Kristine Sørensen
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111762 (2014)
Liver sinusoidal endothelial cells (LSECs) are specialized scavenger cells that mediate high-capacity clearance of soluble waste macromolecules and colloid material, including blood-borne adenovirus. To explore if LSECs function as a sink for other v
Externí odkaz:
https://doaj.org/article/bb3c7d55de0849c68b42fe214a347d56