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Comparison of oral and transdermal administration of rasagiline mesylate on human melanoma tumor growthin vivo

Autor: Richard D. Hamlin, Betsy Huang, Jutaro Shudo, Fatima M. Arjmand, Kevin Dines, Susan R. Meier-Davis, Chad Christianson, Tetsuto Nagata, Jainye Wen

Publikováno v: Cutaneous and Ocular Toxicology. 31:312-317

Transdermal patch administration results in a locally high concentration of drug that induce local toxicity, including tumorogenicity. As a worst-case scenario for consequences of repeated application on neoplastic growth, the melanin-binding drug, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde21b7d161c1d66e21b5f7a72308d37
https://doi.org/10.3109/15569527.2012.676119

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