Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jaimy Jose"'
Autor:
Jaimy Jose, Monira Hoque, Johanna Engel, Syed S. Beevi, Mohamed Wahba, Mariya Ilieva Georgieva, Kendelle J. Murphy, William E. Hughes, Blake J. Cochran, Albert Lu, Francesc Tebar, Andrew J. Hoy, Paul Timpson, Kerry-Anne Rye, Carlos Enrich, Carles Rentero, Thomas Grewal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Cholesterol is considered indispensable for cell motility, but how physiological cholesterol pools enable cells to move forward remains to be clarified. The majority of cells obtain cholesterol from the uptake of Low-Density lipoproteins (LD
Externí odkaz:
https://doaj.org/article/d41d8cbae8614657a10cbd861eb353d6
Autor:
Mai K. L. Nguyen, Jaimy Jose, Mohamed Wahba, Marc Bernaus-Esqué, Andrew J. Hoy, Carlos Enrich, Carles Rentero, Thomas Grewal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7206 (2022)
Cancer cells undergo drastic metabolic adaptions to cover increased bioenergetic needs, contributing to resistance to therapies. This includes a higher demand for cholesterol, which often coincides with elevated cholesterol uptake from low-density li
Externí odkaz:
https://doaj.org/article/c5b9e6d2703944838a467f538399fafe
Autor:
Elsa Meneses-Salas, Ana García-Melero, Patricia Blanco-Muñoz, Jaimy Jose, Marie-Sophie Brenner, Albert Lu, Francesc Tebar, Thomas Grewal, Carles Rentero, Carlos Enrich
Publikováno v:
Cells, Vol 9, Iss 5, p 1152 (2020)
We recently identified elevated annexin A6 (AnxA6) protein levels in Niemann–Pick-type C1 (NPC1) mutant cells. In these cells, AnxA6 depletion rescued the cholesterol accumulation associated with NPC1 deficiency. Here, we demonstrate that elevated
Externí odkaz:
https://doaj.org/article/a90d89b5e21644989dc53990c3e430b8
Autor:
Francesc Tebar, Jaimy Jose, Albert Pol, Esther Pérez-Navarro, Carlos Enrich, Elsa Meneses-Salas, Alba Fajardo, Andrés D. Klein, Mohamed Wahba, Carla Castany-Pladevall, Silvana Zanlungo, Thomas Grewal, Albert Lu, Marta Garcia-Forn, Carles Rentero, Marta Bosch
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Niemann-Pick type C disease (NP-C) is a lysosomal storage disorder characterized by cholesterol accumulation caused by loss-of-function mutations in the Npc1 gene. NP-C disease primarily affects the brain, causing neuronal damage and affecting motor
Autor:
Jaimy Jose, Francesc Tebar, Meryem Köse, Yasmin A. Elmaghrabi, Carlos Enrich, Paul Timpson, Monira Hoque, Thomas Grewal, Patricia Blanco-Muñoz, Syed Sultan Beevi, James R.W. Conway, Carles Rentero, Alexander Swarbrick, Elsa Meneses-Salas
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Annexin A6 (AnxA6), a member of the calcium (Ca2+ ) and membrane binding annexins, is known to stabilize and establish the formation of multifactorial signaling complexes. At the plasma membrane, AnxA6 is a scaffold for protein kinase Cα (PKCα) and
Autor:
Abigail H. Pollock, Jaimy Jose, Carles Rentero, Mohamed Wahba, Marta Bosch, Francesc Tebar, Elsa Meneses-Salas, Thomas Grewal, Stephen E. Moss, Carlos Enrich, Albert Lu, Albert Pol, Patricia Blanco-Muñoz, Katharina Gaus, Mercedes Casado, Anna Alvarez-Guaita, Rafael Artuch
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Background and Aims: Liver regeneration requires the organized and sequential activation of events that lead to restoration of hepatic mass. During this process, other vital liver functions need to be preserved, such as maintenance of blood glucose h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529a736af83ce03b45d5c1d87b0f2abf
http://hdl.handle.net/2445/183738
http://hdl.handle.net/2445/183738
Autor:
Ana García-Melero, Elsa Meneses-Salas, Albert Lu, Carlos Enrich, Jaimy Jose, Francesc Tebar, Patricia Blanco-Muñoz, Marie-Sophie Brenner, Carles Rentero, Thomas Grewal
Publikováno v:
Cells, Vol 9, Iss 1152, p 1152 (2020)
Cells
Dipòsit Digital de la UB
Universidad de Barcelona
Volume 9
Issue 5
Cells
Dipòsit Digital de la UB
Universidad de Barcelona
Volume 9
Issue 5
We recently identified elevated annexin A6 (AnxA6) protein levels in Niemann&ndash
Pick-type C1 (NPC1) mutant cells. In these cells, AnxA6 depletion rescued the cholesterol accumulation associated with NPC1 deficiency. Here, we demonstrate that
Pick-type C1 (NPC1) mutant cells. In these cells, AnxA6 depletion rescued the cholesterol accumulation associated with NPC1 deficiency. Here, we demonstrate that