Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jaime Ortega-Lopez"'
Autor:
Eric Dumonteil, Weihong Tu, Hans Desale, Kelly Goff, Preston Marx, Jaime Ortega-Lopez, Claudia Herrera
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-11 (2024)
Abstract Background A vaccine against Trypanosoma cruzi, the agent of Chagas disease, would be an excellent additional tool for disease control. A recombinant vaccine based on Tc24 and TSA1 parasite antigens was found to be safe and immunogenic in na
Externí odkaz:
https://doaj.org/article/ed8fb005e1f24898a561b81c072d525e
Autor:
Victor Manuel Dzul-Huchim, Maria Jesus Ramirez-Sierra, Pedro Pablo Martinez-Vega, Miguel Enrique Rosado-Vallado, Victor Ermilo Arana-Argaez, Jaime Ortega-Lopez, Fabian Gusovsky, Eric Dumonteil, Julio Vladimir Cruz-Chan, Peter Hotez, María Elena Bottazzi, Liliana Estefania Villanueva-Lizama
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010258 (2022)
BackgroundChagas disease (CD) is caused by Trypanosoma cruzi and affects 6-7 million people worldwide. Approximately 30% of chronic patients develop chronic chagasic cardiomyopathy (CCC) after decades. Benznidazole (BNZ), one of the first-line chemot
Externí odkaz:
https://doaj.org/article/374146e448344e15b0bf078cd3e7e089
Autor:
Ausencio Galindo, Rosario Javier-Reyna, Guillermina García-Rivera, Cecilia Bañuelos, Sarita Montaño, Jaime Ortega-Lopez, Bibiana Chávez-Munguía, Lizbeth Salazar-Villatoro, Esther Orozco
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular trafficking in eukaryotes through the formation of vesicles and membrane fission
Externí odkaz:
https://doaj.org/article/b4e741feae734c6aaa99a103b1b17697
Autor:
Juan Jose de la Cruz, Liliana Villanueva-Lizama, Victor Dzul-Huchim, María-Jesus Ramírez-Sierra, Pedro Martinez-Vega, Miguel Rosado-Vallado, Jaime Ortega-Lopez, Claudia Ivonne Flores-Pucheta, Portia Gillespie, Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, Eric Dumonteil
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 1, Pp 210-219 (2019)
A therapeutic vaccine for human Chagas disease (American trypanosomiasis caused by Trypanosoma cruzi) is under development based on the success of vaccinating mice with DNA constructs expressing the antigens Tc24 and Tc-TSA-1. However, because DNA an
Externí odkaz:
https://doaj.org/article/539cfa6032b84113ab27eea2495a768b
Autor:
Liliana E Villanueva-Lizama, Julio V Cruz-Chan, Amarú Del C Aguilar-Cetina, Luis F Herrera-Sanchez, Jose M Rodriguez-Perez, Miguel E Rosado-Vallado, Maria J Ramirez-Sierra, Jaime Ortega-Lopez, Kathryn Jones, Peter Hotez, Maria Elena Bottazzi, Eric Dumonteil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006240 (2018)
Trypanosoma cruzi antigens TSA-1 and Tc24 have shown promise as vaccine candidates in animal studies. We evaluated here the recall immune response these antigens induce in Chagasic patients, as a first step to test their immunogenicity in humans. We
Externí odkaz:
https://doaj.org/article/9f6642a88b054c54acaac2a76c331737
Autor:
Samuel Lara-Gonzalez, Priscilla Estrella, Carmen Portillo, María E Cruces, Pedro Jimenez-Sandoval, Juliana Fattori, Ana C Migliorini-Figueira, Marisol Lopez-Hidalgo, Corina Diaz-Quezada, Margarita Lopez-Castillo, Carlos H Trasviña-Arenas, Eugenia Sanchez-Sandoval, Armando Gómez-Puyou, Jaime Ortega-Lopez, Rossana Arroyo, Claudia G Benítez-Cardoza, Luis G Brieba
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141747 (2015)
The dimeric nature of triosephosphate isomerases (TIMs) is maintained by an extensive surface area interface of more than 1600 Å2. TIMs from Trichomonas vaginalis (TvTIM) are held in their dimeric state by two mechanisms: a ball and socket interacti
Externí odkaz:
https://doaj.org/article/427e6c8416424f5c82dfbcc25abb4acf
Autor:
Victor Dzul-Huchim, Andrea Alfaro-Chacón, Patricia Novelo-Sarabia, Miguel Rosado-Vallado, Julio Cruz-Chan, Antonio Euan-Canto, Julio Torres-Romero, Fabian Gusovsky, Jaime Ortega-Lopez, Peter Hotez, Maria Elena Bottazzi, Liliana Villanueva-Lizama, Vctor Arana-Argáez
Chagas disease is a chronic infection caused by Trypanosoma cruzi. The first-line drugs approved for treatment have several limitations and are associated with toxicity. The recombinant TSA-1-C4 and Tc24-C4 proteins have been profiled as promising ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13580ef1e8430e01b44dd21db05861de
https://doi.org/10.22541/au.167945777.72745278/v1
https://doi.org/10.22541/au.167945777.72745278/v1
Autor:
Victor Manuel Dzul-Huchim, Maria Jesus Ramirez-Sierra, Pedro Pablo Martinez-Vega, Miguel Enrique Rosado-Vallado, Victor Ermilo Arana-Argaez, Jaime Ortega-Lopez, Fabian Gusovsky, Eric Dumonteil, Julio Vladimir Cruz-Chan, Peter Hotez, María Elena Bottazzi, Liliana Estefania Villanueva-Lizama
BackgroundChagas disease (CD) is caused by Trypanosoma cruzi and affects 6-7 million people worldwide. Approximately 30% of chronic patients develop chronic chagasic cardiomyopathy (CCC) after decades. Benznidazole (BNZ), one of the first-line chemot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459b59eeb3325614e2dba7fee57b62f4
https://doi.org/10.1101/2022.02.16.480638
https://doi.org/10.1101/2022.02.16.480638
Autor:
Verónica Aranda-Chan, Rosa Elena Cárdenas-Guerra, Alejandro Otero-Pedraza, Esdras Enoc Pacindo-Cabrales, Claudia Ivonne Flores-Pucheta, Octavio Montes-Flores, Rossana Arroyo, Jaime Ortega-López
Publikováno v:
Pathogens, Vol 13, Iss 8, p 644 (2024)
Peptidyl-prolyl cis/trans isomerases (PPIases) are present in a wide variety of microorganisms, including protozoan parasites such as Trypanosoma cruzi, Trypanosoma brucei, Trichomonas vaginalis, Leishmania major, Leishmania donovani, Plasmodium falc
Externí odkaz:
https://doaj.org/article/e245bf341a7045f586c3632f9819c359
Autor:
Esly Alejandra Euceda-Padilla, Miriam Guadalupe Mateo-Cruz, Leticia Ávila-González, Claudia Ivonne Flores-Pucheta, Jaime Ortega-López, Daniel Talamás-Lara, Beatriz Velazquez-Valassi, Lidia Jasso-Villazul, Rossana Arroyo
Publikováno v:
Pathogens, Vol 13, Iss 2, p 119 (2024)
Trichomonas vaginalis is the causative agent of trichomoniasis, the most prevalent nonviral, neglected sexually transmitted disease worldwide. T. vaginalis has one of the largest degradomes among unicellular parasites. Cysteine peptidases (CPs) are t
Externí odkaz:
https://doaj.org/article/f374346a629a4db8bab3417aa812cf20