Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jaime Maripillán"'
Autor:
Felipe Villanelo, Peter J. Minogue, Jaime Maripillán, Mauricio Reyna-Jeldes, Joaquin Jensen-Flores, Isaac E. García, Eric C. Beyer, Tomás Pérez-Acle, Viviana M. Berthoud, Agustín D. Martínez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Members of the β-subfamily of connexins contain an intracellular pocket surrounded by amino acid residues from the four transmembrane helices. The presence of this pocket has not previously been investigated in members of the α-
Externí odkaz:
https://doaj.org/article/06defa631d704d8c9d7c419ba703475f
Autor:
Oscar Jara, Jaime Maripillán, Fanny Momboisse, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7246 (2024)
Connexins (Cxs) are transmembrane proteins that assemble into gap junction channels (GJCs) and hemichannels (HCs). Previous researches support the involvement of Rho GTPases and actin microfilaments in the trafficking of Cxs, formation of GJCs plaque
Externí odkaz:
https://doaj.org/article/9ba926a964484e14aa81a6579f880d2e
Autor:
Ana C. Abbott, Isaac E. García, Felipe Villanelo, Carolina Flores-Muñoz, Ricardo Ceriani, Jaime Maripillán, Joel Novoa-Molina, Cindel Figueroa-Cares, Tomas Pérez-Acle, Juan C. Sáez, Helmuth A. Sánchez, Agustín D. Martínez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of c
Externí odkaz:
https://doaj.org/article/4a2519a57af545099c4f91f689d29670
Autor:
Cristina Pinto, Danilo B. Medinas, Francisco Fuentes-Villalobos, Jaime Maripillán, Ariel F. Castro, Agustín D. Martínez, Nelson Osses, Claudio Hetz, Juan P. Henríquez
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104497- (2019)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. A 20% of familial ALS cases are associated with mutations in the gene coding for superoxide dismutase 1 (SOD1). The accumulation of abnormal aggre
Externí odkaz:
https://doaj.org/article/4a0d45cd6707447e8bd3fb8034d9623c
Autor:
Carolina Flores-Muñoz, Jaime Maripillán, Jacqueline Vásquez-Navarrete, Joel Novoa-Molina, Ricardo Ceriani, Helmuth A. Sánchez, Ana C. Abbott, Caroline Weinstein-Oppenheimer, Donald I. Brown, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1069 (2021)
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Externí odkaz:
https://doaj.org/article/147cbf8208f44eea86a4905123c43b40
Autor:
Donald I. Brown, Jaime Maripillán, Carolina Flores-Muñoz, Joel Novoa-Molina, Ana C Abbott, Caroline Weinstein-Oppenheimer, Ricardo Ceriani, Jacqueline Vásquez-Navarrete, Isaac E. García, Ana M. Cárdenas, Agustín D. Martínez, Helmuth A. Sánchez
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1069, p 1069 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1069, p 1069 (2021)
Volume 22
Issue 3
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Autor:
Chidinma Adanna Okolo, Jack Jonathan Maran, Amy Watts, Jaime Maripillan, Maria Harkiolaki, Agustín D. Martínez, Colin R. Green, Odunayo Omolola Mugisho
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e27888- (2024)
Non-junctional connexin43 (Cx43) plasma membrane hemichannels have been implicated in several inflammatory diseases, particularly playing a role in ATP release that triggers activation of the inflammasome. Therapies targeting the blocking of the hemi
Externí odkaz:
https://doaj.org/article/e17a063b57c24edb96e75c070ffc7e0f
Autor:
Nelson Osses, Juan Pablo Henríquez, Cristina Pinto, Ariel F. Castro, Claudio Hetz, Danilo B. Medinas, Jaime Maripillán, Agustín D. Martínez, Francisco Fuentes-Villalobos
Publikováno v:
Neurobiology of Disease, Vol 130, Iss, Pp 104497-(2019)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. A 20% of familial ALS cases are associated with mutations in the gene coding for superoxide dismutase 1 (SOD1). The accumulation of abnormal aggre
Autor:
Fernanda M. Rozas-Villanueva, Viviana P. Orellana, Rodrigo Alarcón, Jaime Maripillan, Agustin D. Martinez, Ivan E. Alfaro, Mauricio A. Retamal
Publikováno v:
Cells, Vol 13, Iss 13, p 1150 (2024)
Background: Extravillous trophoblasts (EVTs) form stratified columns at the placenta–uterus interface. In the closest part to fetal structures, EVTs have a proliferative phenotype, whereas in the closest part to maternal structures, they present a
Externí odkaz:
https://doaj.org/article/d0113118426c43eea9903d6e5448bf3f
Autor:
Ricardo Ceriani, Juan C. Sáez, Jorge E. Contreras, Angelina Palacios-Muñoz, Jaime Maripillán, Oscar Jara, Carlos Gonzalez, Agustín D. Martínez, Tomas Perez-Acle, Pablo Olivero, Isaac E. García, Jayalakshimi Ramachandran
Publikováno v:
The Journal of investigative dermatology, vol 135, iss 5
The Journal of investigative dermatology
The Journal of investigative dermatology
Mutations in Cx26 gene are found in most cases of human genetic deafness. Some mutations produce syndromic deafness associated with skin disorders, like the Keratitis-Ichthyosis-Deafness syndrome (KID). Because in the human skin connexin 26 (Cx26) is