MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS

Autor: Jesús A. Pérez-Cabello, Lucía Silvera-Carrasco, Jaime M. Franco, Vivian Capilla-González, Alexandros Armaos, María Gómez-Lima, Raquel García-García, Xin Wen Yap, M. Magdalena Leal-Lasarte, Deepti Lall, Robert H. Baloh, Salvador Martínez, Yoshihiko Miyata, Gian G. Tartaglia, Ritwick Sawarkar, Mario García-Dominguez, David Pozo, Cintia Roodveldt

Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease affecting motor neurons and characterized by microglia-mediated neurotoxic inflammation whose underlying mechanisms remain incompletely understood. In this work we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::009874c33f6e71a3dc6ed51509372f09
https://doi.org/10.1101/2023.01.23.524851

213-OR: Obesity-Induced Astrogliosis Is Regulated by the Diabesity Factor HMG20A

Autor: José A. Guerrero-Martínez, Benoit R. Gauthier, David Pozo, Silvana Y. Romero-Zerbo, Jaime M. Franco, Petra I. Lorenzo, José C. Reyes, Esther Fuente-Martín, Francisco Javier Bermúdez-Silva, Nadia Cobo-Vuilleumier, Jesús Ángel Pérez-Cabello, Manuel Álvarez-Dolado, José Manuel Mellado-Gil

Publikováno v: Diabetes. 69

It is well established that systemic glucose homeostasis is imparted by an intricate cross-talk among several organs including the central nervous system (CNS) and pancreatic islets. In analogy to islet beta cells, hypothalamic astrocytes are glucose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::268e358916c27f1070ad2e50939ca6a9
https://doi.org/10.2337/db20-213-or

Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification

Autor: Ricardo Franco, Jaime M. Franco, Pedro Quaresma, Patrick J. Merkling, Carlos Caro, Eulália Pereira, María L. García-Martín, Jose Luis Royo, Manuel Leal, David Pozo, Ana Paula Zaderenko, Jose Maria Oliva-Montero

Publikováno v: Nanomaterials
Volume 9
Issue 2
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Nanomaterials, Vol 9, Iss 2, p 256 (2019)

Progress in the field of biocompatible SERS nanoparticles has promising prospects for biomedical applications. In this work, we have developed a biocompatible Raman probe by combining anisotropic silver nanoparticles with the dye rhodamine 6G followe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff76d6c00bb26c592b28c3d230cb5e3
https://pubmed.ncbi.nlm.nih.gov/30781838

Determination of Valanis model parameters in a bolted lap joint: Experimental and numerical analyses of frictional dissipation

Autor: Jaime M. Franco, Francisco J. Medel, Javier Abad

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

In this work, Valanis model parameters, and their variation with bolt preload, were determined for a bolted lap joint, which consisted in two steel plates held together by a metric 12 screw. For this purpose, a series of transitory non-linear analyse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b220db7b320ab834cd262f72e5b6b2c
https://doi.org/10.1016/j.ijmecsci.2014.09.014

Cell tracking, survival, and differentiation capacity of adipose-derived stem cells after engraftment in rat tissue

Autor: Antonio Ayala, M. Guzman-Chozas, Sandro Argüelles, Mercedes Cano, José Antonio Pintor-Toro, Remedios Guillén‐Sanz, Jaime M. Franco, Mario F. Muñoz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Adipose tissue is an important source of adipose derived stem cells (ADSCs). These cells have the potential of being used for certain therapies, in which the main objective is to recover the function of a tissue/organ affected by a disease. In order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460aa39b9eb5b266e5506786408e2d83
https://pubmed.ncbi.nlm.nih.gov/29319169