Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jaime Hughes"'
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/5f41db01abd74951b7211fe8e579a8b0
Publikováno v:
Vaccines, Vol 12, Iss 6, p 572 (2024)
Oral vaccines, unlike injected, induce intestinal secretory immunoglobulin A (sIgA) mimicking our natural defense against gut pathogens. We previously observed sIgA responses after administering the Clostridioides difficile colonisation factor CD0873
Externí odkaz:
https://doaj.org/article/c56aef2ce4dd46f9b1cba496a0b0315c
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1086 (2022)
Clostridioides difficile is an opportunistic gut pathogen which causes severe colitis, leading to significant morbidity and mortality due to its toxins, TcdA and TcdB. Two intra-muscular toxoid vaccines entered Phase III trials and strongly induced t
Externí odkaz:
https://doaj.org/article/36a7524c41744b6ca455617d2de281c0
Autor:
Cansu Karyal, Panayiota Palazi, Jaime Hughes, Rhys C. Griffiths, Ruby R. Persaud, Patrick J. Tighe, Nicholas J. Mitchell, Ruth Griffin
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1453 (2021)
Mucosal vaccination aims to prevent infection mainly by inducing secretory IgA (sIgA) antibody, which neutralises pathogens and enterotoxins by blocking their attachment to epithelial cells. We previously demonstrated that encapsulated protein antige
Externí odkaz:
https://doaj.org/article/4865710cb0b34b4aa4bfbbc66ee850e1
Autor:
Cansu Karyal, Jaime Hughes, Michelle L. Kelly, Jeni C. Luckett, Philip V. Kaye, Alan Cockayne, Nigel P. Minton, Ruth Griffin
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 306 (2021)
Clostridioides difficile is the main cause of health-care-associated infectious diarrhoea. Toxins, TcdA and TcdB, secreted by this bacterium damage colonic epithelial cells and in severe cases this culminates in pseudomembranous colitis, toxic megaco
Externí odkaz:
https://doaj.org/article/e611c52d6d454bf3b11ceedab05891c6
Akademický článek
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Autor:
Jennifer Sullivan, Anna Rae Montano, Heather Davila, Marlena Shin, Chelsea Hawley, Jaime Hughes, Kelly O'Malley, Camilla Pimentel
Publikováno v:
Innovation in Aging. 6:390-390
The application of implementation science in aging research has been growing. To our knowledge, there has been no study detailing the Dissemination and Implementation (D&I) Models utilized in aging research. The goal of this citation review is to fur
Autor:
Sandipan Datta, Eugene S. Lee, Kevin C. Chun, Natalia Jaime-Hughes, Ankur Gupta, Zachary T. Irwin, Richard C. Anderson, Elise A. Newton
Publikováno v:
Journal of vascular surgery. 75(4)
Background Abdominal aortic aneurysm (AAA) screening has demonstrated to be cost-effective in reducing AAA-related morbidity and all-cause mortality. However, the downstream care costs of an implemented AAA screening in clinical practice have not bee
Autor:
Ruth Griffin, Jeni Luckett, Alan Cockayne, Nigel P. Minton, Philip Kaye, Cansu Karyal, Jaime Hughes, Michelle L. Kelly
Publikováno v:
Microorganisms
Microorganisms, Vol 9, Iss 306, p 306 (2021)
Microorganisms, Vol 9, Iss 306, p 306 (2021)
Clostridioides difficile is the main cause of health-care-associated infectious diarrhoea. Toxins, TcdA and TcdB, secreted by this bacterium damage colonic epithelial cells and in severe cases this culminates in pseudomembranous colitis, toxic megaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e1f80351676a61f5c99c4852dc6116
Autor:
Jaime Hughes, Nancy Morrow-Howell
Publikováno v:
Innovation in Aging
Implementation science, defined by NIH as “the scientific study of the use of strategies to adopt and integrate evidence-based health interventions,” continues to grow within research, education, and practice-based settings. Building on principle