Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jaime Hincapie-Garcia"'
In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach
Autor:
Maria I. Zapata-Cardona, Lizdany Florez-Alvarez, Ariadna L. Guerra-Sandoval, Mateo Chvatal-Medina, Carlos M. Guerra-Almonacid, Jaime Hincapie-Garcia, Juan C. Hernandez, Maria T. Rugeles, Wildeman Zapata-Builes
Publikováno v:
AIMS Microbiology, Vol 9, Iss 1, Pp 20-40 (2023)
Background: Drug repurposing is a valuable strategy for rapidly developing drugs for treating COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against SARS-CoV-2 in vitro and in silico. Methods: The cytotoxicity
Externí odkaz:
https://doaj.org/article/0638fc4e7acc4b158a2372696f49d638
Autor:
María I. Zapata-Cardona, Lizdany Flórez-Álvarez, Wildeman Zapata-Builes, Ariadna L. Guerra-Sandoval, Carlos M. Guerra-Almonacid, Jaime Hincapié-García, María T. Rugeles, Juan C. Hernandez
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
This article evaluated the in vitro antiviral effect of atorvastatin (ATV) against SARS-CoV-2 and identified the interaction affinity between this compound and two SARS-CoV-2 proteins. The antiviral activity of atorvastatin against this virus was eva
Externí odkaz:
https://doaj.org/article/1f23186d39e647ad8adcf620cd4ca06c