Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jaime Franco Pinto"'
Publikováno v:
Organic & Biomolecular Chemistry. 20:1888-1892
Activity of O6-methylguanine-DNA-methyltransferase (MGMT) can be monitored in real time using chemosensors that generate an emissive guanine analogue thienoguanine (thGN).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb82acf467dfd486f4c13025bcff436
https://doi.org/10.1039/d2ob00208f
https://doi.org/10.1039/d2ob00208f
Autor:
Oksana Reznichenko, Denis Leclercq, Jaime Franco Pinto, Liliane Mouawad, Valérie Gabelica, Anton Granzhan
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, 2022, ⟨10.1002/chem.202202427⟩
Chemistry-A European Journal, 2022, ⟨10.1002/chem.202202427⟩
International audience; G-quadruplexes (G4s), secondary structures adopted by guanine-rich DNA and RNA sequences, are implicated in numerous biological processes and have been suggested as potential drug targets. Accordingly, there is an increasing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d575d2af9d9c2cbac965c6e40bc54ab
https://doi.org/10.1002/chem.202202427
https://doi.org/10.1002/chem.202202427
Publikováno v:
Organicbiomolecular chemistry. 20(9)
The fluorescence properties of an emissive guanine surrogate, thienoguanine (thGN, 2-aminothieno[3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bc4133ca7d0c19aad7ee4243c8688db
https://pubmed.ncbi.nlm.nih.gov/35174383
https://pubmed.ncbi.nlm.nih.gov/35174383
Autor:
Jaime, Franco Pinto, Alexandra, Fillion, Patricia, Duchambon, Sophie, Bombard, Anton, Granzhan
Publikováno v:
European journal of medicinal chemistry. 227
O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8ccc9c0ac2bef3a73dc1e24406a6d5c
https://pubmed.ncbi.nlm.nih.gov/34731767
https://pubmed.ncbi.nlm.nih.gov/34731767
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2022, 227, pp.113909. ⟨10.1016/j.ejmech.2021.113909⟩
European Journal of Medicinal Chemistry, 2022, 227, pp.113909. ⟨10.1016/j.ejmech.2021.113909⟩
International audience; O6-Methylguanine-DNA-methyltransferase (MGMT) is a key DNA repair enzyme involved in chemoresistance to DNA-alkylating anti-cancer drugs such as Temozolomide (TMZ) through direct repair of drug-induced O6-methylguanine residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd3224c5e6ff105d48b14bb33c0f814