Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Jaime F, Modiano"'
Autor:
Rose H. Dicovitsky, Jill T. Schappa, Ashley J. Schulte, Haeree P. Lang, Ellen Kuerbitz, Sarah Roberts, Taylor A. DePauw, Mitzi Lewellen, Amber L. Winter, Kathy Stuebner, Michelle Buettner, Kelly Reid, Kelly Bergsrud, Sara Pracht, Andrea Chehadeh, Caitlin Feiock, M. Gerard O’Sullivan, Tim Carlson, Alexandra R. Armstrong, Danielle Meritet, Michael S. Henson, Brenda J. Weigel, Jaime F. Modiano, Antonella Borgatti, Daniel A. Vallera
Publikováno v:
Toxins, Vol 16, Iss 9, p 376 (2024)
EGFR-targeted therapies are efficacious, but toxicity is common and can be severe. Urokinase type plasminogen activator receptor (uPAR)-targeted drugs are only emerging, so neither their efficacy nor toxicity is fully established. Recombinant eBAT wa
Externí odkaz:
https://doaj.org/article/6505ce6cd7b5471f92672f457ebc37f6
Autor:
Abigail S Jarosz, Amanda L Pendleton, Michael J Lashbrook, Erica Cech, Madison Altieri, Austin Kunch, Jaime F Modiano, Julia V Halo
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011083 (2023)
Despite the absence of a confirmed exogenously replicating retrovirus in Canis lupus familiaris (C. familiaris), past retroviral infections are evident in the genomes of living animals via the presence of endogenous retroviruses (ERVs). Although gamm
Externí odkaz:
https://doaj.org/article/a97a8ccac21d405fb1b2aab8ff9460f4
Autor:
Kelly M. Makielski, Aaron L. Sarver, Michael S. Henson, Kathleen M. Stuebner, Antonella Borgatti, Lukkana Suksanpaisan, Caitlin Preusser, Alexandru-Flaviu Tabaran, Ingrid Cornax, M. Gerard O’Sullivan, Andrea Chehadeh, Donna Groschen, Kelly Bergsrud, Sara Pracht, Amber Winter, Lauren J. Mills, Marc D. Schwabenlander, Melissa Wolfe, Michael A. Farrar, Gary R. Cutter, Joseph S. Koopmeiners, Stephen J. Russell, Jaime F. Modiano, Shruthi Naik
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100736- (2023)
Osteosarcoma is a devastating bone cancer that disproportionally afflicts children, adolescents, and young adults. Standard therapy includes surgical tumor resection combined with multiagent chemotherapy, but many patients still suffer from metastati
Externí odkaz:
https://doaj.org/article/f4f7cab98bbe4ae5a0cfe31df10cc42c
Autor:
Amelia G. Campbell, Davis M. Seelig, Joan D. Beckman, Katie M. Minor, Daniel A. Heinrich, Steven G. Friedenberg, Jaime F. Modiano, Eva Furrow
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 4, Pp 1237-1247 (2022)
Abstract Background Myelofibrosis often lacks an identifiable cause in dogs. In humans, most primary myelofibrosis cases develop secondary to driver mutations in JAK2, CALR, or MPL. Objectives To determine the prevalence of variants in JAK2, CALR, or
Externí odkaz:
https://doaj.org/article/a7315aa5647f45fa93563d64851d9eb2
Publikováno v:
Aging and Cancer, Vol 3, Iss 1, Pp 3-19 (2022)
Abstract Cancer is among the most common causes of death for dogs (and cats) and humans in the developed world, even though it is uncommon in wildlife and other domestic animals. We provide a rationale for this observation based on recent advances in
Externí odkaz:
https://doaj.org/article/c8eaeac0ad9542d5beae4c6db42ceb10
Autor:
Robert Hullsiek, Yunfang Li, Kristin M. Snyder, Sam Wang, Da Di, Antonella Borgatti, Chae Lee, Peter F. Moore, Cong Zhu, Chiara Fattori, Jaime F. Modiano, Jianming Wu, Bruce Walcheck
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human natural killer (NK) cells can target tumor cells in an antigen-specific manner by the recognition of cell bound antibodies. This process induces antibody-dependent cell-mediated cytotoxicity (ADCC) and is exclusively mediated by the low affinit
Externí odkaz:
https://doaj.org/article/70dbc22e61c946d5853bbec8c44b6bd1
Autor:
Aaron L. Sarver, Lauren J. Mills, Kelly M. Makielski, Nuri A. Temiz, Jinhua Wang, Logan G. Spector, Subbaya Subramanian, Jaime F. Modiano
Publikováno v:
Cancer Genetics. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce3c99a00cc28e908fec151a0d8adaa
https://doi.org/10.1016/j.cancergen.2023.05.001
https://doi.org/10.1016/j.cancergen.2023.05.001
Autor:
Brandon J. Diessner, Tracy A. Marko, Ruth M. Scott, Andrea L. Eckert, Kathleen M. Stuebner, Ann E. Hohenhaus, Kim A. Selting, David A. Largaespada, Jaime F. Modiano, Logan G. Spector
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 3216-3226 (2019)
Abstract Background Canine osteosarcoma (OS) is a relevant spontaneous model for human OS. Identifying similarities in clinical characteristics associated with metastasis at diagnosis in both species may substantiate research aimed at using canine OS
Externí odkaz:
https://doaj.org/article/bdb1f5ecc2cf4dddb654d426edc73fd8
Autor:
Sean J Judge, Mio Yanagisawa, Ian R Sturgill, Sarah B Bateni, Alicia A Gingrich, Jennifer A Foltz, Dean A Lee, Jaime F Modiano, Arta M Monjazeb, William T N Culp, Robert B Rebhun, William J Murphy, Michael S Kent, Robert J Canter
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0224775 (2020)
We have previously reported radiation-induced sensitization of canine osteosarcoma (OSA) to natural killer (NK) therapy, including results from a first-in-dog clinical trial. Here, we report correlative analyses of blood and tissue specimens for sign
Externí odkaz:
https://doaj.org/article/a39dda521d974edeb699d527357c19a9
Autor:
Daniel E. Shore, Thamotharampillai Dileepan, Jaime F. Modiano, Marc K. Jenkins, Bethanie J. H. Stadler
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Epitope-specific CD4+ T lymphocytes were magnetically enriched using ferromagnetic Ni and Fe-Au nanowires coated with a monomer containing a major histocompatibility complex class II-bound peptide epitope (pMHCII). The enriched lymphocytes w
Externí odkaz:
https://doaj.org/article/d9899e4430bb42ccb37827b9dc8de565