Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jaime Darce"'
Autor:
Chakravarthy Chennareddy, Katherine J. L. Jackson, Shantoria J. Brown, Carl W. Davis, Wan Cheung Cheung, Megan McCausland, Rebecca Gerkin, Susanne L. Linderman, Aneesh K. Mehta, Jens Wrammert, Rafi Ahmed, Scott D. Boyd, Cathy Y. Chang, Edmund K. Waller, Jaime Darce
Publikováno v:
Science
Immunity after the flu shot The seasonal flu shot is currently recommended each year because the influenza viral strains in circulation are continuously changing and because the antibody responses produced by the vaccine decline over time. In a human
Autor:
Ramit Mehr, Jaime Darce, Travis Ichikawa, Iñaki Sanz, Alexander F. Rosenberg, Christopher M. Tipton, F. Eun-Hyung Lee, Christopher F. Fucile, Chungwen Wei, Ron J. Feldman, Scott A. Jenks, Wan Cheung Cheung, Sandra M Schieferl, Asiya Seema Chida, Ivan V. Gregoretti, Jennifer Hom
Publikováno v:
Nature immunology
Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells (ASCs) whose origin, diversity and contribution to serum autoantibodies remain unknown. Here, deep sequencing, proteomic profiling of autoantibodies and single-c
Autor:
Rachel E. Niec, Christophe Benoist, Yuri P. Rubtsov, Jaime Darce, Alexander Y. Rudensky, Diane Mathis, Li Li, Steven Z. Josefowicz
Publikováno v:
Science. 329:1667-1671
Self-Renewing T Cells The homeostasis of cell populations within an organism can be achieved through a variety of mechanisms, including the differentiation of precursor populations, self-renewal of terminally differentiated cells, or by programming c
Autor:
Jaime Darce, Dan R. Littman, Tatsuichiro Shima, Hsin Jung Wu, Christophe Benoist, Kimie Hattori, Ivaylo I. Ivanov, Diane Mathis, Yoshinori Umesaki
Publikováno v:
Immunity. 32(6):815-827
SummaryCommensal microbes can have a substantial impact on autoimmune disorders, but the underlying molecular and cellular mechanisms remain largely unexplored. We report that autoimmune arthritis was strongly attenuated in the K/BxN mouse model unde
Autor:
Stephen R. Lutz, Michael Lewis, Jaime Darce, Roy Scialdone, Evans Burford, Herbert Haack, Krystyna Zuberek Hincman, Michael R. Nelson, Matthew Ren Silver, Christopher A. Manning
Publikováno v:
Cancer Research. 76:4595-4595
The epidermal growth factor receptor (EGFR) is a cell-surface receptor for members of the epidermal growth factor family (EGF-family). EGFR dimerizes upon ligand binding, which leads to autophosphorylation, downstream signaling and ultimately interna
Autor:
Jaime Darce, Stephen Lutz, Sandra Schieferl, Elizabeth Moreno, Ravi Ramenani, James Wieler, Lana Popova, Jason Beaudet, Xiaowu Zhang, Shuji Sato, Sean Beausoleil, Roberto Polakiewicz, Wan Cheung
Publikováno v:
The Journal of Immunology. 190:48.3-48.3
Previous studies aimed at determining the affinity maturation pathways of monoclonal antibodies during an immunization have relied on comparing germ-line with mature forms of antibodies present in either transgenic B cell receptor mouse models or by
Autor:
Li Li, Daniela Cipolletta, Christophe Benoist, Junko Nishio, Alexander Y. Rudensky, Diane Mathis, Jaime Darce, Dipayan Rudra
Publikováno v:
Immunity. (5):731-741
SummaryMaintenance of lymphoid homeostasis in a number of immunological and inflammatory contexts is served by a variety of regulatory T (Treg) cell subtypes and depends on interaction of the transcription factor FoxP3 with specific transcriptional c