Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jaime A Costales"'
Autor:
Carolina Proaño-Bolaños, Giovanna Morán-Marcillo, Nina Espinosa de los Monteros-Silva, Sebastián Bermúdez-Puga, Mateo A. Salazar, Ailín Blasco-Zúñiga, Sebastián Cuesta, Carolina Molina, Franklin Espinosa, Lorena Meneses, Patricio Rojas-Silva, Sonia Zapata Mena, Fabián E. Sáenz, Miryan Rivera I., Jaime A. Costales
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Chagas disease, leishmaniasis, and malaria are major parasitic diseases disproportionately affecting the underprivileged population in developing nations. Finding new, alternative anti-parasitic compounds to treat these diseases is crucial b
Externí odkaz:
https://doaj.org/article/8c6f724342844de3b832b9d3c9f6bf05
Autor:
Patricia Mora‐Criollo, Reetobrata Basu, Yanrong Qian, Kevin Funk, Stephen Bell, Jonathan A. Young, Edward O. List, Jaime A. Costales, Jaime Guevara‐Aguirre, Mario J. Grijalva, John J. Kopchick
Publikováno v:
FEBS Open Bio, Vol 13, Iss 7, Pp 1346-1356 (2023)
Chagas disease (CD) is one of the most devasting parasitic diseases in the Americas, affecting 7–8 million people worldwide. In vitro and in vivo experiments have demonstrated that growth hormone (GH) serum levels decrease as CD progresses. Interes
Externí odkaz:
https://doaj.org/article/63343503754d4c3b9c22ff8271705ef3
Autor:
Andrea López-Rosero, Rachel Sippy, Anna M Stewart-Ibarra, Sadie J Ryan, Erin Mordecai, Froilán Heras, Efraín Beltrán, Jaime A Costales, Marco Neira
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011908 (2024)
We performed an arboviral survey in mosquitoes from four endemic Ecuadorian cities (Huaquillas, Machala, Portovelo and Zaruma) during the epidemic period 2016-2018. Collections were performed during the pre-rainy season (2016), peak transmission seas
Externí odkaz:
https://doaj.org/article/f3a73f1b566e47ab81c2cd71098b17fd
Autor:
Jalil Maiguashca Sánchez, Salem Oduro Beffi Sueto, Philipp Schwabl, Mario J. Grijalva, Martin S. Llewellyn, Jaime A. Costales
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Trypanosoma cruzi, the causative agent of Chagas disease, and T. rangeli are kinetoplastid parasites endemic to Latin America. Although closely related to T. cruzi and capable of infecting humans, T. rangeli is non-pathogenic. Bot
Externí odkaz:
https://doaj.org/article/2c79b3f688f7450baf390104e553ca9c
Autor:
Manuel Calvopina, Gabriela Segovia, William Cevallos, Yosselin Vicuña, Jaime A. Costales, Angel Guevara
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-5 (2020)
Abstract Background Chagas disease is caused by the haemoflagellate protozoan Trypanosoma cruzi. Currently, T. cruzi recognizes seven discrete typing units (DTUs): TcI to TcVI and Tcbat. The genetic diversity of T. cruzi is suspected to influence the
Externí odkaz:
https://doaj.org/article/a8ae6d2658914e43a503b4bb76856d18
Autor:
Luis E Hernandez-Castro, Anita G Villacís, Arne Jacobs, Bachar Cheaib, Casey C Day, Sofía Ocaña-Mayorga, Cesar A Yumiseva, Antonella Bacigalupo, Björn Andersson, Louise Matthews, Erin L Landguth, Jaime A Costales, Martin S Llewellyn, Mario J Grijalva
Publikováno v:
PLoS Genetics, Vol 18, Iss 2, p e1010019 (2022)
Accurate prediction of vectors dispersal, as well as identification of adaptations that allow blood-feeding vectors to thrive in built environments, are a basis for effective disease control. Here we adopted a landscape genomics approach to assay gen
Externí odkaz:
https://doaj.org/article/e171cc29d004469b94b3fd7a2b9d5b58
Autor:
Eden R. Ferreira, Alexis Bonfim-Melo, Barbara A. Burleigh, Jaime A. Costales, Kevin M. Tyler, Renato A. Mortara
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Understanding how Trypanosoma cruziT. cruzi
Externí odkaz:
https://doaj.org/article/ed632c6db9a24e08bb12f2b97c9c28c3
Autor:
Philipp Schwabl, Hideo Imamura, Frederik Van den Broeck, Jaime A. Costales, Jalil Maiguashca-Sánchez, Michael A. Miles, Bjorn Andersson, Mario J. Grijalva, Martin S. Llewellyn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi, the causative agent of Chagas disease. These findings have implications for the epidemiology of the disease in endemic regions and challenge existing ideas that the
Externí odkaz:
https://doaj.org/article/4b305acc8f064921b66238a36c6173f8
Autor:
Carlos Talavera-López, Louisa A. Messenger, Michael D. Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos, Daniella C. Bartholomeu, José E. Calzada, Azael Saldaña, Juan David Ramírez, Felipe Guhl, Sofía Ocaña-Mayorga, Jaime A. Costales, Rodion Gorchakov, Kathryn Jones, Melissa S. Nolan, Santuza M. R. Teixeira, Hernán José Carrasco, Maria Elena Bottazzi, Peter J. Hotez, Kristy O. Murray, Mario J. Grijalva, Barbara Burleigh, Edmundo C. Grisard, Michael A. Miles, Björn Andersson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Trypanosoma cruzi, a zoonotic kinetoplastid protozoan parasite, is the causative agent of American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex genome, the parasite displays a highly diverse repertoire of surface mo
Externí odkaz:
https://doaj.org/article/a4cd59512a324280b349602a5bf83648
Autor:
Andrea Vela, Marco Coral-Almeida, Denis Sereno, Jaime A Costales, Christian Barnabé, Simone Frédérique Brenière
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009269 (2021)
BackgroundChagas disease, a neglected tropical disease endemic to Latin America caused by the parasite Trypanosoma cruzi, currently affects 6-7 million people and is responsible for 12,500 deaths each year. No vaccine exists at present and the only t
Externí odkaz:
https://doaj.org/article/604cd402429047fc834a11b8c2cecdde