Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Jaime A Arias"'
Autor:
Yi-Ting Wang, Joseph Therriault, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S. Mathotaarachchi, Jenna Stevenson, Firoza Z. Lussier, Andréa L. Benedet, Tharick A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Females represent approximately 70% of the Alzheimer’s disease (AD) cases and the literature has proposed a connection between the decreased estrogen levels during menopause and an increased AD risk. Previous investigations have
Externí odkaz:
https://doaj.org/article/daf9534a01764ab599de980ae7f154aa
Autor:
Julie Ottoy, Min Su Kang, Jazlynn Xiu Min Tan, Lyndon Boone, Reinder Vos de Wael, Bo-yong Park, Gleb Bezgin, Firoza Z. Lussier, Tharick A. Pascoal, Nesrine Rahmouni, Jenna Stevenson, Jaime Fernandez Arias, Joseph Therriault, Seok-Jun Hong, Bojana Stefanovic, JoAnne McLaurin, Jean-Paul Soucy, Serge Gauthier, Boris C. Bernhardt, Sandra E. Black, Pedro Rosa-Neto, Maged Goubran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Alzheimer’s disease (AD) is a brain network disorder where pathological proteins accumulate through networks and drive cognitive decline. Yet, the role of network connectivity in facilitating this accumulation remains unclear. Using in-viv
Externí odkaz:
https://doaj.org/article/fde529232e944d638ac5830511c20cef
Autor:
Marcel S. Woo, Joseph Therriault, Erin M. Jonaitis, Rachael Wilson, Rebecca E. Langhough, Nesrine Rahmouni, Andrea Lessa Benedet, Nicholas J. Ashton, Cécile Tissot, Juan Lantero-Rodriguez, Arthur C. Macedo, Stijn Servaes, Yi-Ting Wang, Jaime Fernandez Arias, Seyyed Ali Hosseini, Tobey J. Betthauser, Firoza Z. Lussier, Robert Hopewell, Gallen Triana-Baltzer, Hartmuth C. Kolb, Andreas Jeromin, Eliane Kobayashi, Gassan Massarweh, Manuel A. Friese, Jesse Klostranec, Paolo Vilali, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Sterling C. Johnson, Pedro Rosa-Neto
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105413- (2024)
Summary: Background: Blood-based disease staging across the Alzheimer's disease (AD) continuum holds the promise to identify individuals that profit from disease-modifying therapies. We set out to identify Braak V+ (Braak V and/or VI) tau PET-positiv
Externí odkaz:
https://doaj.org/article/fb10423af32b4438978a55cda015eda3
Autor:
Lazaro M. Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Thomas K. Karikari, Nicholas J. Ashton, Andréa L. Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C. Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Neuronal dysfunction and cognitive deterioration in Alzheimer’s disease (AD) are likely caused by multiple pathophysiological factors. However, mechanistic evidence in humans remains scarce, requiring improved non-invasive techniques and i
Externí odkaz:
https://doaj.org/article/d1d394702b194a57a434755661c25a8f
Autor:
Lazaro M. Sanchez-Rodriguez, Ahmed F. Khan, Quadri Adewale, Gleb Bezgin, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Hongxiu Jiang, Xiaoqian Chai, Felix Carbonell, Pedro Rosa-Neto, Yasser Iturria-Medina
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The molecular mechanisms underlying neuronal dysfunction in Alzheimer’s disease (AD) remain uncharacterized. Here, we identify genes, molecular pathways and cellular components associated with whole-brain dysregulation caused by amyloid-beta (Aβ)
Externí odkaz:
https://doaj.org/article/1657c77c5c334d1eb95796dc2572b831
Autor:
Marcel S. Woo, Johanna Nilsson, Joseph Therriault, Nesrine Rahmouni, Ann Brinkmalm, Andrea L. Benedet, Nicholas J. Ashton, Arthur C. Macedo, Stijn Servaes, Yi-Ting Wang, Cécile Tissot, Jaime Fernandez Arias, Seyyed Ali Hosseini, Mira Chamoun, Firoza Z. Lussier, Thomas K. Karikari, Jenna Stevenson, Christina Mayer, João Pedro Ferrari-Souza, Eliane Kobayashi, Gassan Massarweh, Manuel A. Friese, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Introduction Synaptic loss is closely associated with tau aggregation and microglia activation in later stages of Alzheimer’s disease (AD). However, synaptic damage happens early in AD at the very early stages of tau accumulation. It remai
Externí odkaz:
https://doaj.org/article/8072bbc5673044c19bd12aa939e0a997
Publikováno v:
Data in Brief, Vol 49, Iss , Pp 109323- (2023)
Concentration of particulate matter directly affects air quality and human health. Three sources of information were used in this work to generate datasets on this matter at the Fontibón county in Bogota D.C., Colombia. The first source was a Davis
Externí odkaz:
https://doaj.org/article/e1562ec4a7d7463890df512d280e5b3c
Autor:
Joseph Therriault, Firoza Z. Lussier, Cécile Tissot, Mira Chamoun, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Gleb Bezgin, Stijn Servaes, Peter Kunach, Yi‐Ting Wang, Jaime Fernandez‐Arias, Marie Vermeiren, Tharick A. Pascoal, Gassan Massarweh, Paolo Vitali, Jean‐Paul Soucy, Paramita Saha‐Chaudhuri, Serge Gauthie, Pedro Rosa‐Neto
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract Introduction [18F]AZD4694 is an amyloid beta (Aβ) imaging agent used in several observational studies and clinical trials. However, no studies have yet published data on longitudinal Aβ accumulation measured with [18F]AZD4694. Methods We a
Externí odkaz:
https://doaj.org/article/0743f6a4d88b477e9305928c3c9f2449
Publikováno v:
Forest Systems, Vol 32, Iss 1 (2023)
Aim of study: To determine the importance in terms of carbon sequestration of dispersed trees in pasture lands as a greenhouse gas (GHG) mitigation measure. Area of study: The study was carried out in the municipality of Agustin Codazzi (Cesar Dep
Externí odkaz:
https://doaj.org/article/5cb67fcdcfc34c4dbe518642fca0ca6f
Publikováno v:
Journal of Chest Surgery, Vol 54, Iss 6, Pp 539-542 (2021)
Resection and reconstruction of the chest wall for the radical surgical treatment of malignant soft tissue tumors are currently considered a substantial challenge for thoracic surgeons. We present an unusual case of infantile fibrosarcoma with trop
Externí odkaz:
https://doaj.org/article/cd4bbdfd49964c86aee9006ae2079ed3