Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jaikumar Duraiswamy"'
Autor:
Hans Schreiber, Yusuke Nakamura, Wolfgang Uckert, Ralph R. Weichselbaum, Jaikumar Duraiswamy, Ainhoa Arina, Christian Idel, Kazuma Kiyotani, Poh Yin Yew, Karin Schreiber, Boris Engels, Matthias Leisegang
Purpose: Cancers usually contain multiple unique tumor-specific antigens produced by single amino acid substitutions (AAS) and encoded by somatic nonsynonymous single nucleotide substitutions. We determined whether adoptively transferred T cells can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1077eb9ea3122f52f933a7fb913a2574
https://doi.org/10.1158/1078-0432.c.6523295.v1
https://doi.org/10.1158/1078-0432.c.6523295.v1
Autor:
Hans Schreiber, Yusuke Nakamura, Wolfgang Uckert, Ralph R. Weichselbaum, Jaikumar Duraiswamy, Ainhoa Arina, Christian Idel, Kazuma Kiyotani, Poh Yin Yew, Karin Schreiber, Boris Engels, Matthias Leisegang
Supplementary Methods - Contains detailed information on whole exome and RNA sequencing, variant calling, TCR gene transfer, and longitudinal imaging Supplementary Fig. S1 - Pipeline for exome/RNA analysis and neoepitope prediction Supplementary Fig.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152acad500d53e6fc038965a880846e6
https://doi.org/10.1158/1078-0432.22456394.v1
https://doi.org/10.1158/1078-0432.22456394.v1
PDF file, 74K, PD-1 or PD-L1 blockade increases immune activation of TILs in ID8 tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc5447331d3ee4c765aef06add29537
https://doi.org/10.1158/0008-5472.22398791.v1
https://doi.org/10.1158/0008-5472.22398791.v1
PDF file, 23K, Upregulation of suppressive population of MDSCs and pDCs following GVAX and FVAX vaccination, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3786398b8902d67829b4a595eaba87
https://doi.org/10.1158/0008-5472.22398785
https://doi.org/10.1158/0008-5472.22398785
Supplementary Figure 1 - PDF file 56K, Splenic T cells in CT26-bearing mice express low levels of PD-1 or CTLA-4. Representative and summary data showing the frequency of PD-1 and CTLA-4 expression on CD8+ (A) and CD4+ (B) T cells from spleen of CT26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f81296c2ff3ecde49a863d24135972
https://doi.org/10.1158/0008-5472.22395080
https://doi.org/10.1158/0008-5472.22395080
PDF file, 20K, Combination therapy increases ovarian tumor antigen (mesothelin) specific inflammatory cytokine production by ID8 TILs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e182d17d365b48b377e8b93b7f4ff3
https://doi.org/10.1158/0008-5472.22398779.v1
https://doi.org/10.1158/0008-5472.22398779.v1
Supplementary Figure 3 - PDF file 26K, in vivo depletion of total CD8+ and CD4+ T cells totally abolished CT26 tumor regression. Survival of mice inoculated with 0.5 x 106 CT26 tumor cells and injected i.p. with �CD4 (GK1.5, 500 �g) or �CD8 ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29967382fa34e26084193d45bc2c9f97
https://doi.org/10.1158/0008-5472.22395071.v1
https://doi.org/10.1158/0008-5472.22395071.v1
PDF file, 78K, Gating strategy & representative stains of MDSC and Treg cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88228b695f45ad7dcb36d7649e188278
https://doi.org/10.1158/0008-5472.22398800.v1
https://doi.org/10.1158/0008-5472.22398800.v1
Supplementary Text - PDF file 121K, Supplementary Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bd6a88c786e70ebd66507837a7f366
https://doi.org/10.1158/0008-5472.22395062.v1
https://doi.org/10.1158/0008-5472.22395062.v1