Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jaichandran, Sivalingam"'
Autor:
Viknesvaran Selvarajan, Denise Bei Lin Teo, Chaw-Chiea Chang, Yuen Ling Ng, Nge Cheong, Jaichandran Sivalingam, Soo Hean Gary Khoo, Adison Wong, Bernard Liat Wen Loo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cell and gene therapies are an innovative solution to various severe diseases and unfulfilled needs. Adoptive cell therapy (ACT), a form of cellular immunotherapies, has been favored in recent years due to the approval of chimeric antigen receptor CA
Externí odkaz:
https://doaj.org/article/3d9028b801ef462494f238a602103ffe
Autor:
Jaichandran Sivalingam, Hong Yu Chen, Bin-Xia Yang, Zhong Ri Lim, Alan Tin Lun Lam, Tsung Liang Woo, Allen Kuan-Liang Chen, Shaul Reuveny, Yuin-Han Loh, Steve Kah-Weng Oh
Publikováno v:
Haematologica, Vol 103, Iss 7 (2018)
Externí odkaz:
https://doaj.org/article/2a34731852e94429b4777b14464e96c7
Autor:
SuE Yu, Svetlan Vassilev, Zhong Ri Lim, Jaichandran Sivalingam, Alan Tin Lun Lam, Valerie Ho, Laurent Renia, Benoit Malleret, Shaul Reuveny, Steve Kah Weng Oh
Publikováno v:
Cell proliferation. 55(8)
Large-scale generation of universal red blood cells (RBCs) from O-negative (O-ve) human induced pluripotent stem cells (hiPSCs) holds the potential to alleviate worldwide shortages of blood and provide a safe and secure year-round supply. Mature RBCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766d7f9836acee3ae050912a3af72c9d
https://pubmed.ncbi.nlm.nih.gov/35289971
https://pubmed.ncbi.nlm.nih.gov/35289971
Autor:
Steve Oh, Jaichandran Sivalingam
Publikováno v:
Cell and Gene Therapy Insights. 5:483-504
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885dc25fb13c9b42f463d751ab5fa0b5
https://doi.org/10.18609/cgti.2019.054
https://doi.org/10.18609/cgti.2019.054
Autor:
Irene Kee, In Chin Song, Chin Yong Kiong, Ajit J. Nirmal, Edgar Macabe Pena, Jaichandran Sivalingam, Sze Sing Lee, Frederic Chua, Oi Lian Kon, Kristoffer A. Gales, Wai Har Ng, Bryan Ogden
Publikováno v:
Journal of Cellular and Molecular Medicine
Genetically modified FVIII‐expressing autologous bone marrow‐derived mesenchymal stromal cells (BMSCs) could cure haemophilia A. However, culture‐expanded BMSCs engraft poorly in extramedullary sites. Here, we compared the intramedullary cavity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11117bbc7b8cd92f3bfa4cdb35b3cb0a
http://europepmc.org/articles/PMC6010829
http://europepmc.org/articles/PMC6010829
Autor:
Tsung Liang Woo, Allen Chen, Steve Oh, Bin-Xia Yang, Zhong Ri Lim, Yuin-Han Loh, Shaul Reuveny, A. Lam, Jaichandran Sivalingam, Hong Yu Chen
Publikováno v:
Haematologica. 103:e279-e283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d06a55665440ab7de2dff62e8afba8f
https://doi.org/10.3324/haematol.2017.180919
https://doi.org/10.3324/haematol.2017.180919
Autor:
Nelson K F Chen, Jen San Wong, Irene H C Kee, Siang Hui Lai, Choon Hua Thng, Wai Har Ng, Robert T H Ng, Soo Yong Tan, Shu Yen Lee, Mark E H Tan, Jaichandran Sivalingam, Pierce K H Chow, Oi Lian Kon
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1734 (2008)
BackgroundCurrent gene- and cell-based therapies have significant limitations which impede widespread clinical application. Taking diabetes mellitus as a paradigm, we have sought to overcome these limitations by ex vivo electrotransfer of a nonviral
Externí odkaz:
https://doaj.org/article/d6d641e5934441eda05c41c85f05a2af
Autor:
Jaichandran Sivalingam, Yuin-Han Loh, Steve Oh, Benoit Malleret, A. Lam, Z. Lim, Shaul Reuveny
Publikováno v:
Cytotherapy. 23:S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30a2e72200db27c837591127b66f5371
https://doi.org/10.1016/s1465324921002760
https://doi.org/10.1016/s1465324921002760
Autor:
Steve Oh, Allen Chen, Shaul Reuveny, Jaichandran Sivalingam, Yuin-Han Loh, Bin Xia Yang, Alan Tin-Lun Lam, Hong Yu Chen
Publikováno v:
Tissue Engineering Part C: Methods. 22:765-780
In vitro generation of red blood cells (RBCs) from human embryonic stem cells and human induced pluripotent stem cells appears to be a promising alternate approach to circumvent shortages in donor-derived blood supplies for clinical applications. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01e714475d0d43ad5f1eae6a3526285
https://doi.org/10.1089/ten.tec.2015.0579
https://doi.org/10.1089/ten.tec.2015.0579
Autor:
Sebastian Maurer-Stroh, Dimitar Kenanov, Oi Lian Kon, Wai Har Ng, Hao Han, Ajit J. Nirmal, Jaichandran Sivalingam, Sze Sing Lee, Jeyakumar Masilamani, Toan Thang Phan
Publikováno v:
Molecular Therapy
Costly coagulation factor VIII (FVIII) replacement therapy is a barrier to optimal clinical management of hemophilia A. Therapy using FVIII-secreting autologous primary cells is potentially efficacious and more affordable. Zinc finger nucleases (ZFN)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e732cfd4d98ec3911ad6d9f782b62951