Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jai Yoon Sul"'
Autor:
Hyun-Bum Kim, Quentin Brosseau, Julia Radzio, Jinhui Wang, Hiromi Muramatsu, Da Kuang, M. Sean Grady, H. Isaac Chen, John A. Wolf, Alexandra V. Ulyanova, Tamas Bartfai, Junhyong Kim, Norbert Pardi, Jai-Yoon Sul, Paulo Arratia, James Eberwine
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Multi-RNA co-transfection is starting to be employed to stimulate immune responses to SARS-CoV-2 viral infection. While there are good reasons to utilize such an approach, there is little background on whether there are synergistic RNA-dependent cell
Externí odkaz:
https://doaj.org/article/cdc17219cd1044c0a5d55323f4af4300
Autor:
Hyun-Bum Kim, Jacqueline Morris, Kevin Miyashiro, Tõnis Lehto, Ülo Langel, James Eberwine, Jai-Yoon Sul
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102436- (2021)
Summary: Ethanol (EtOH) abuse induces significant mortality and morbidity worldwide because of detrimental effects on brain function. Defining the contribution of astrocytes to this malfunction is imperative to understanding the overall EtOH effects
Externí odkaz:
https://doaj.org/article/8a873a83823d4e4a9e1672810a900d9d
Autor:
James Eberwine, Junhyong Kim, Ron C. Anafi, Steven Brem, Maja Bucan, Stephen A. Fisher, M. Sean Grady, Amy E. Herr, David Issadore, Hyejoong Jeong, HyunBum Kim, Daeyeon Lee, Stanislav Rubakhin, Jai-Yoon Sul, Jonathan V. Sweedler, John A. Wolf, Kenneth S. Zaret, James Zou
Publikováno v:
Nat Methods
We argue that the study of single-cell subcellular organelle omics is needed to understand and regulate cell function. This requires and is being enabled by new technology development.
Autor:
Jacqueline Morris, Young-Ji Na, Hua Zhu, Jae-Hee Lee, Hoa Giang, Alexandra V. Ulyanova, Gordon H. Baltuch, Steven Brem, H. Isaac Chen, David K. Kung, Timothy H. Lucas, Donald M. O’Rourke, John A. Wolf, M. Sean Grady, Jai-Yoon Sul, Junhyong Kim, James Eberwine
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2706-2713 (2017)
Summary: A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for identification of variants present at the single-mitochondrion level in individual mouse and h
Externí odkaz:
https://doaj.org/article/27a7caa8a52541c2a8d3b84b4ce4f7e0
Autor:
Jennifer M. Spaethling, Young-Ji Na, Jaehee Lee, Alexandra V. Ulyanova, Gordon H. Baltuch, Thomas J. Bell, Steven Brem, H. Isaac Chen, Hannah Dueck, Stephen A. Fisher, Marcela P. Garcia, Mugdha Khaladkar, David K. Kung, Timothy H. Lucas Jr., Donald M. O’Rourke, Derek Stefanik, Jinhui Wang, John A. Wolf, Tamas Bartfai, M. Sean Grady, Jai-Yoon Sul, Junhyong Kim, James H. Eberwine
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 791-803 (2017)
Investigation of human CNS disease and drug effects has been hampered by the lack of a system that enables single-cell analysis of live adult patient brain cells. We developed a culturing system, based on a papain-aided procedure, for resected adult
Externí odkaz:
https://doaj.org/article/dfca0d124ee0410cac03e2216d6c2535
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 114-125 (2013)
Protein synthesis in neuronal dendrites underlies long-term memory formation in the brain. Local translation of reporter mRNAs has demonstrated translation in dendrites at focal points called translational hotspots. Various reports have shown that hu
Externí odkaz:
https://doaj.org/article/9e6e918f9541432db35c146ffa6dc359
Autor:
James Eberwine, Jai-Yoon Sul, Hyun Bum Kim, Ivan J. Dmochowski, Linlin Yang, Dora von Trentini
Publikováno v:
ChemPhotoChem
Light activation is an effective way to impart spatiotemporal control over oligonucleotide probes that are widely applied for gene expression regulation and target function investigation. Among the major oligonucleotide caging strategies, cyclization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcd3efb2b5d05bd0fe2a68a908e9418
https://europepmc.org/articles/PMC9012482/
https://europepmc.org/articles/PMC9012482/
Autor:
Hyun-Bum, Kim, Jacqueline, Morris, Kevin, Miyashiro, Tõnis, Lehto, Ülo, Langel, James, Eberwine, Jai-Yoon, Sul
Publikováno v:
iScience. 24(5)
Ethanol (EtOH) abuse induces significant mortality and morbidity worldwide because of detrimental effects on brain function. Defining the contribution of astrocytes to this malfunction is imperative to understanding the overall EtOH effects due to th
Publikováno v:
ChemBioChem. 19:1250-1254
Light-activated ("caged") antisense oligonucleotides are powerful molecules for regulating gene expression at submicron spatial resolution through the focal modulation of endogenous cellular processes. Cyclized caged oligos are particularly promising
Autor:
David K. Kung, Steven Brem, Junhyong Kim, Hua Zhu, Jaehee Lee, Donald M. O'Rourke, James Eberwine, Hoa Giang, Jacqueline Morris, Jai-Yoon Sul, Alexandra V. Ulyanova, Timothy H. Lucas, Young Ji Na, Gordon H. Baltuch, John A. Wolf, M. Sean Grady, H. Isaac Chen
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2706-2713 (2017)
Summary: A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for identification of variants present at the single-mitochondrion level in individual mouse and h