Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jai S, Rudra"'
Autor:
Megan A. Files, Kubra F. Naqvi, Tais B. Saito, Tara M. Clover, Jai S. Rudra, Janice J. Endsley
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Heterologous vaccine regimens could extend waning protection in the global population immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We demonstrate that pulmonary delivery of peptide nanofibers (PNFs) bearing an Ag85B CD4+
Externí odkaz:
https://doaj.org/article/74cb267c345f461e8f9ffd236df85864
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Development of novel immunization approaches to combat a growing list of emerging and ancient infectious agents is a global health priority. Intensive efforts over the last several decades have identified alternative approaches to improve upon tradit
Externí odkaz:
https://doaj.org/article/2391c80efb884d2597ee572461a7469b
Autor:
Matthew B. Huante, Tais B. Saito, Rebecca J. Nusbaum, Kubra F. Naqvi, Sadhana Chauhan, Robert L. Hunter, Jeffrey K. Actor, Jai S. Rudra, Mark A. Endsley, Joshua G. Lisinicchia, Benjamin B. Gelman, Janice J. Endsley
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased risk of drug resistance development. Concurrent infection with HIV, including in those rece
Externí odkaz:
https://doaj.org/article/cd4e3d98969049a594a05d8680fa4ed0
Autor:
Charles B. Chesson, Matthew Huante, Rebecca J. Nusbaum, Aida G. Walker, Tara M. Clover, Jagannath Chinnaswamy, Janice J. Endsley, Jai S. Rudra
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Bacillus Calmette-Guerin (BCG) is the only vaccine against TB and has limited protection efficacy, which wanes past adolescence. Multifunctional CD8+ T cells (IFN-γ+/TNF-α+/IL-2+) are associated with lower reactivation risk and enhanced co
Externí odkaz:
https://doaj.org/article/5703a72574d74332afa1078b39195189
Autor:
Federico Scala, Miroslav N. Nenov, Elizabeth J. Crofton, Aditya K. Singh, Oluwarotimi Folorunso, Yafang Zhang, Brent C. Chesson, Norelle C. Wildburger, Thomas F. James, Musaad A. Alshammari, Tahani K. Alshammari, Hannah Elfrink, Claudio Grassi, James M. Kasper, Ashley E. Smith, Jonathan D. Hommel, Cheryl F. Lichti, Jai S. Rudra, Marcello D’Ascenzo, Thomas A. Green, Fernanda Laezza
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 555-567 (2018)
Summary: Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na+ channel Nav1.6
Externí odkaz:
https://doaj.org/article/dc94cfdd1eef4764a9b23adba0a07db4
Autor:
Jai S. Rudra, Arshad Khan, Tara M. Clover, Janice J. Endsley, Andrew Zloza, Jin Wang, Chinnaswamy Jagannath
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 9136-9143 (2017)
Externí odkaz:
https://doaj.org/article/c8951b13481d4ae98c3b42c85d9788df
Autor:
Paresh C. Shrimali, Sheng Chen, Rachel Dreher, Matthew K. Howard, Jeremy Buck, Darren Kim, Jai S. Rudra, Meredith E. Jackrel
De novo designed peptides that self-assemble into cross-β rich fibrillar biomaterials have been pursued as an innovative platform for the development of adjuvant- and inflammation-free vaccines. However, they share structural properties similar to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f006a714365a6335db6c00af967403f
https://doi.org/10.1101/2022.09.09.507367
https://doi.org/10.1101/2022.09.09.507367
Publikováno v:
Acta biomaterialia
Currently approved replication-competent and inactivated vaccines are limited by excessive reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently immunogenic without co-administering exogenous adjuvants. Self-assembl
Autor:
Zain P. Clapacs, Paresh C. Shrimali, Giriraj Lokhande, Akhilesh K. Gaharwar, Megan A. Files, Darren D. Kim, Conor L. O'Neill, Jai S. Rudra
Publikováno v:
Biomacromolecules. 23(3)
Alginate hydrogels are widely used for tissue engineering and regenerative medicine due to their excellent biocompatibility. A facile and commonly used strategy to crosslink alginate is the addition of Ca2+ that leads to hydrogelation. However, extra
Autor:
Syed A. Zamin, Jian Shi, Jorge A. Belgodere, Bert C. Lynn, Katie Hamel, Ryan M. Kalinoski, Jai S. Rudra, Carlos E. Astete, Jangwook P. Jung, Joseph C. Penrod
Publikováno v:
ACS applied bio materials. 2(8)
Three-dimensional matrices of collagen type I (Col I) are widely used in tissue engineering applications for its abundance in many tissues, bioactivity with many cell types, and excellent biocompatibility. Inspired by the structural role of lignin in