Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jai G. Marathe"'
Autor:
Emilie Mausser, Ellena Nador, Joseph A. Politch, Michael R. Pauly, Jai G. Marathe, Thomas R. Moench, Larry Zeitlin, Kevin J. Whaley, Deborah J. Anderson
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
High rates of unintended pregnancies worldwide indicate a need for more accessible and acceptable methods of contraception. We have developed a monoclonal antibody, the Human Contraception Antibody (HCA), for use by women in vaginal films and rings f
Externí odkaz:
https://doaj.org/article/5a9999709243450cb529b912f0f767f4
Autor:
Gabriela Baldeon-Vaca, Jai G. Marathe, Joseph A. Politch, Emilie Mausser, Jeffrey Pudney, James Doud, Ellena Nador, Larry Zeitlin, Michael Pauly, Thomas R. Moench, Miles Brennan, Kevin J. Whaley, Deborah J. Anderson
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103478- (2021)
Background: Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs)
Externí odkaz:
https://doaj.org/article/f960369930a04b50a35050bf6a2ee689
Autor:
Robert W, Finberg, Madiha, Ashraf, Boris, Julg, Folusakin, Ayoade, Jai G, Marathe, Nicolas C, Issa, Jennifer P, Wang, Siraya, Jaijakul, Lindsey R, Baden, Carol, Epstein
Publikováno v:
Open Forum Infectious Diseases
Background Favipiravir is used to treat influenza, and studies demonstrate that it has antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods We performed a randomized, open-label, multicenter, phase 2 proof-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea39a4fcc0bd5abf0a6ecb1729b3b63f
https://doi.org/10.1093/ofid/ofab563
https://doi.org/10.1093/ofid/ofab563
Autor:
Deborah J. Anderson, Emilie Mausser, Jeffrey Pudney, Gabriela Baldeon-Vaca, Miles B. Brennan, Kevin J. Whaley, Thomas R. Moench, Michael H. Pauly, James Doud, Larry Zeitlin, Joseph A. Politch, Ellena Nador, Jai G Marathe
Publikováno v:
EBioMedicine, Vol 69, Iss, Pp 103478-(2021)
EBioMedicine
EBioMedicine
Background Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972e8ecbe428dd36ac941ef8032e762d
http://www.sciencedirect.com/science/article/pii/S2352396421002711
http://www.sciencedirect.com/science/article/pii/S2352396421002711
Autor:
Rachel L Epstein, Laura F. White, Heather E Hsu, Nancy S. Miller, Sara Lodi, Heather Sperring, Joshua A. Barocas, Yian Xiao, Melissa Hofman, Benjamin P. Linas, Jai G Marathe, Tara C. Bouton
Publikováno v:
Open Forum Infectious Diseases
To determine the association between immunosuppression and time to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) clearance, we studied 3758 adults retested following initial SARS-CoV-2 infection. Cox pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3471451ebb027b082e1322d7853e3d
https://doi.org/10.1093/ofid/ofab164
https://doi.org/10.1093/ofid/ofab164
Autor:
Sabrina A. Assoumou, Rebecca H Burns, H Dawn Fukuda, Simeon D. Kimmel, Jessica L Taylor, Glorimar Ruiz-Mercado, Samantha Johnson, Cassandra Pierre, Jai G Marathe
Publikováno v:
Open Forum Infectious Diseases
Massachusetts is one of the epicenters of the opioid epidemic and has been severely impacted by injection-related viral and bacterial infections. A recent increase in newly diagnosed human immunodeficiency virus (HIV) infections among persons who inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deb17b61c2f78eea3624a24405c25f8
https://doi.org/10.1093/ofid/ofab208
https://doi.org/10.1093/ofid/ofab208
Autor:
Kate M. Guthrie, Miles B. Brennan, Kevin J. Whaley, Tara Nyhuis, Karen T. Tashima, Thomas R. Moench, Deborah J. Anderson, Joseph A. Politch, Susan Cu-Uvin, Larry Zeitlin, Jai G Marathe, Kenneth H. Mayer, Hans M. L. Spiegel, Howard Cabral
Publikováno v:
PLoS Medicine, Vol 18, Iss 2, p e1003495 (2021)
PLoS Medicine
PLoS Medicine
Background MB66 film is a multipurpose prevention technology (MPT) product with monoclonal antibodies (mAbs) against HIV-1 (VRC01-N) and HSV-1 and 2 (HSV8-N). The mAbs were produced by transient expression in Nicotiana benthamiana (N). We conducted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cfffd83bcc7837a8d8aa3adbd2bc94
https://doaj.org/article/080a0cd6780b4946ae5836420c4ae97a
https://doaj.org/article/080a0cd6780b4946ae5836420c4ae97a
Publikováno v:
Journal of Infectious Diseases. 210:S609-S615
Human immunodeficiency virus (HIV)–infected leukocytes have been detected in genital secretions from HIV-infected men and women and may play an important role in the sexual transmission of HIV. However, they have been largely overlooked in studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc8eaf23ac8d8294db29960870f2042
https://doi.org/10.1093/infdis/jiu390
https://doi.org/10.1093/infdis/jiu390
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 71(6)
The superficial layers of the human vaginal epithelium, which form an interface between host and environment, are comprised of dead flattened cells that have undergone a terminal cell differentiation program called cornification. This entails extrusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b039c766b1c3e79af895e20b5de302dd
https://pubmed.ncbi.nlm.nih.gov/24661416
https://pubmed.ncbi.nlm.nih.gov/24661416
Publikováno v:
American journal of physiology. Cell physiology. 299(6)
Enterotoxins elaborated by Vibrio cholerae and Escherichia coli cannot elicit fluid secretion in the absence of functional cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels. After enterotoxin exposure, CFTR channels are rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48af22e860e3ee35e5cca9ed065f895a
https://pubmed.ncbi.nlm.nih.gov/20844248
https://pubmed.ncbi.nlm.nih.gov/20844248