Zobrazeno 1 - 10
of 2 635
pro vyhledávání: '"Jahn M"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: The increased risk of post-menopausal women developing abnormalities of heart function emphasises the requirement to understand the effect of declining oestrogen levels on cardiac electrophysiology and structure, and investigate possible
Externí odkaz:
https://doaj.org/article/11d4aaa2e9674035aa8c18bdb6de14a3
Autor:
Xiaoran Li, Jie Lu, Quancheng Kan, Xiaoli Li, Qiong Fan, Yaqing Li, Ruixia Huang, Ana Slipicevic, Hiep Phuc Dong, Lars Eide, Junbai Wang, Hongquan Zhang, Viktor Berge, Mariusz Adam Goscinski, Gunnar Kvalheim, Jahn M. Nesland, Zhenhe Suo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-20 (2017)
Abstract Flavopiridol (FP) is a pan-cyclin dependent kinase inhibitor, which shows strong efficacy in inducing cancer cell apoptosis. Although FP is potent against most cancer cells in vitro, unfortunately it proved less efficacious in clinical trial
Externí odkaz:
https://doaj.org/article/bc89935f75804aa4884f583426b81b31
Autor:
Xiaoran Li, Mantas Grigalavicius, Yaqing Li, Xiaoli Li, Yali Zhong, Ruixia Huang, Dandan Yu, Viktor Berge, Mariusz Adam Goscinski, Gunnar Kvalheim, Jahn M Nesland, Zhenhe Suo
Publikováno v:
Tumor Biology, Vol 39 (2017)
Our earlier study revealed that long-term ethidium bromide application causes mitochondrial DNA depletion in human prostate cancer DU145 cell line (DU145 MtDP ), and this DU145 MtDP subline appears to have expanded CD44 Bright cell population than it
Externí odkaz:
https://doaj.org/article/577bc6eb48434bea960039bf71b0268f
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121398 (2015)
Cyclin B1-CDK1 complex plays an important role in the regulation of cell cycle. Activation of Cyclin B1 and CDK1 and the formation of the complex in G2/M are under multiple regulations involving many regulators such as isoforms of 14-3-3 and CDC25 an
Externí odkaz:
https://doaj.org/article/6052623884d146c08cfef14c412ef9e0
Autor:
Pedro Kringen, Anna Bergamaschi, Eldri Undlien Due, Yun Wang, Elda Tagliabue, Jahn M. Nesland, Aune Nehman, Neeme Tönisson, Anne-Lise Børresen-Dale
Publikováno v:
BioTechniques, Vol 39, Iss 5, Pp 755-761 (2005)
Mutations in the tumor suppressor gene TP53 are associated with a wide range of different cancers and may have prognostic and therapeutic implications. Methods for rapid and sensitive detection of mutations in this gene are therefore required. In ord
Externí odkaz:
https://doaj.org/article/1a0e3cc94d264256a306237aae6b6115
Autor:
Rolf I. Skotheim, Vera M. Abeler, Jahn M. Nesland, Sophie D. Fosså, Ruth Holm, Urs Wagner, Vivi Ann Flørenes, Nina Aass, Olli P. Kallioniemi, Ragnhild A. Lothe
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 5, Pp 397-404 (2003)
By the use of high-throughput molecular technologies, the number of genes and proteins potentially relevant to testicular germ cell tumor (TGCT) and other diseases will increase rapidly. In a recent transcriptional profiling, we demonstrated the over
Externí odkaz:
https://doaj.org/article/227ec519942542169734aeae1d690fa9
Autor:
Jarle eBruun, Matthias eKolberg, Jahn M. Nesland, Arild eNesbakken, Aud eSvindland, Ragnhild A. Lothe
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Robust biomarkers that can precisely stratify patients according to treatment needs are in great demand. The literature is inconclusive for most reported prognostic markers for colorectal cancer (CRC). Hence, adequately reported studies in large repr
Externí odkaz:
https://doaj.org/article/6822d8e318c14bcdbaa80a38d169a6e5
Autor:
Ruixia Huang, Dan Wu, Yuan Yuan, Xiaoran Li, Ruth Holm, Claes G Trope, Jahn M Nesland, Zhenhe Suo
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112209 (2014)
The stem cell factor (SCF) receptor CD117 (c-kit), is widely used for identification of hematopoietic stem cells and cancer stem cells. Moreover, CD117 expression in carcinoma cells indicates a poor prognosis in a variety of cancers. However the pote
Externí odkaz:
https://doaj.org/article/afc828edd7e5467684d19eed23582dda
Autor:
Lin Thorstensen, Hanne Qvist, Sverre Heim, Gerrit-Jan Liefers, Jahn M. Nesland, Karl-Erik Giercksky, Ragnhild A. Lothe
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 6, Pp 514-522 (2000)
Cytogenetic and molecular genetic analyses of colorectal adenomas and carcinomas have shown that loss of the distal part of chromosome arm 1p is common, particularly in tumors of the left colon. Because the importance of 1p loss in colorectal cancer
Externí odkaz:
https://doaj.org/article/4d62cb03e61b4552ae9849e6a8a1605f
Autor:
José M. Lopes, Einar Hannisdal, Bodil Bjerkehagen, Øyvind S. Bruland, Håvard E. Danielsen, Erik O. Pettersend, Manuel Sobrinho-Simões, Jahn M. Nesland
Publikováno v:
Analytical Cellular Pathology, Vol 16, Iss 1, Pp 45-62 (1998)
Controversy still exists regarding the validity of parameters commonly used in the evaluation of prognosis of patients with synovial sarcoma (SS). Forty-nine cases of previously untreated primary SS (23 females and 26 males, ranging in age from 7 to
Externí odkaz:
https://doaj.org/article/f67ff69ecbfc49a79c564f69bfe563de