Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jahan S Khalili"'
Autor:
Tania G Rodríguez-Cruz, Shujuan Liu, Jahan S Khalili, Mayra Whittington, Minying Zhang, Willem Overwijk, Gregory Lizée
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22939 (2011)
Dendritic cell (DC)-mediated presentation of MHC class I (MHC-I)/peptide complexes is a crucial first step in the priming of CTL responses, and the cytoplasmic tail of MHC-I plays an important role in modulating this process. Several species express
Externí odkaz:
https://doaj.org/article/e373aa8263854226b33e9a5771cefa6e
Autor:
Gregory Lizée, Patrick Hwu, Michael A. Davies, Laszlo G. Radvanyi, Chantale Bernatchez, Fenge Li, Wanleng Deng, Mayra Whittington, Shujuan Liu, Tania Rodriguez-Cruz, Jahan S. Khalili, Amjad Talukder, Brenda Melendez, Zeming Chen, Sherille D. Bradley
Supplemental Figure 1. Three melanoma cell lines (CHL1, Mel888, and WM793) were treated with DMSO (0), 10uM, or 50uM of dabrafenib (BRAFi) for 3 hours. Whole cell lysates were prepared, and levels of phospho-ERK and total ERK were analyzed by immunob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788bf3b568ad9e09fe2ab3424cef6b35
https://doi.org/10.1158/2326-6066.22537288.v1
https://doi.org/10.1158/2326-6066.22537288.v1
Autor:
Gregory Lizée, Patrick Hwu, Michael A. Davies, Laszlo G. Radvanyi, Chantale Bernatchez, Fenge Li, Wanleng Deng, Mayra Whittington, Shujuan Liu, Tania Rodriguez-Cruz, Jahan S. Khalili, Amjad Talukder, Brenda Melendez, Zeming Chen, Sherille D. Bradley
Supplemental Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0100c7676217050ebd8f92e9581d1b55
https://doi.org/10.1158/2326-6066.22537285.v1
https://doi.org/10.1158/2326-6066.22537285.v1
Autor:
Cassian Yee, Gregory Lizée, Jason Roszik, Kyung-Mi Lee, Patrick Hwu, David Hawke, Chantale Bernatchez, Scott E. Woodman, Bih-Fang Pan, Caitlin Creasy, Junmei Wang, Jahan S. Khalili, Kyle R. Jackson, Sherille D. Bradley, Brenda Melendez, Ke Pan, Kwanghee Kim, Seon A. Lim, Amjad H. Talukder, Jungsun Park
S1. Ectopic expression of HLA allotypes in melanoma cell line Mel888. S2. SLC45A2 expression is restricted to melanoma tumor cells. S3. SLC45A2 gene expression in Cancer Cell Line Encyclopedia (CCLE) cell lines. S4. Quantitative comparison of SLC45A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475b2ea7e5cc04f87ee8d16c2d7f8864
https://doi.org/10.1158/2326-6066.22537814.v1
https://doi.org/10.1158/2326-6066.22537814.v1
Autor:
Gregory Lizée, Patrick Hwu, Michael A. Davies, Laszlo G. Radvanyi, Chantale Bernatchez, Fenge Li, Wanleng Deng, Mayra Whittington, Shujuan Liu, Tania Rodriguez-Cruz, Jahan S. Khalili, Amjad Talukder, Brenda Melendez, Zeming Chen, Sherille D. Bradley
Oncogene activation in tumor cells induces broad and complex cellular changes that contribute significantly to disease initiation and progression. In melanoma, oncogenic BRAFV600E has been shown to drive the transcription of a specific gene signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fae9a00906e9304905e73dc122d5b0a
https://doi.org/10.1158/2326-6066.c.6548380.v1
https://doi.org/10.1158/2326-6066.c.6548380.v1
Autor:
Cassian Yee, Gregory Lizée, Jason Roszik, Kyung-Mi Lee, Patrick Hwu, David Hawke, Chantale Bernatchez, Scott E. Woodman, Bih-Fang Pan, Caitlin Creasy, Junmei Wang, Jahan S. Khalili, Kyle R. Jackson, Sherille D. Bradley, Brenda Melendez, Ke Pan, Kwanghee Kim, Seon A. Lim, Amjad H. Talukder, Jungsun Park
Cytotoxic T lymphocyte (CTL)–based immunotherapies have had remarkable success at generating objective clinical responses in patients with advanced metastatic melanoma. Although the melanocyte differentiation antigens (MDA) MART-1, PMEL, and tyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5e73a3c865f36a93ae179951dcbd0e3
https://doi.org/10.1158/2326-6066.c.6548561.v1
https://doi.org/10.1158/2326-6066.c.6548561.v1
Autor:
Gregory Lizée, Patrick Hwu, Jennifer A. Wargo, Michael A. Davies, Richard E. Davis, Laszlo G. Radvanyi, Elizabeth Grimm, Suhendan Ekmekcioglu, Chantale Bernatchez, Richard W. Joseph, Min Zhang, Yufeng Li, Dennie T. Frederick, Zachary A. Cooper, Minying Zhang, Chengwen Liu, Seth Wardell, Mayra Whittington, Tania G. Rodríguez-Cruz, Shujuan Liu, Jahan S. Khalili
PDF file, 212K, (A) H&E staining of representative, A375 human xenograft tumor sections excised from NOD/SCID mice. Prior to excision, mice with established tumors were treated for 3 days with either PLX4720 or DMSO vehicle control. Magnification: 4x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f77b8a82cddbbc65e1c3ffb71cfedb
https://doi.org/10.1158/1078-0432.22455612
https://doi.org/10.1158/1078-0432.22455612
Autor:
Gregory Lizée, Patrick Hwu, Jennifer A. Wargo, Michael A. Davies, Richard E. Davis, Laszlo G. Radvanyi, Elizabeth Grimm, Suhendan Ekmekcioglu, Chantale Bernatchez, Richard W. Joseph, Min Zhang, Yufeng Li, Dennie T. Frederick, Zachary A. Cooper, Minying Zhang, Chengwen Liu, Seth Wardell, Mayra Whittington, Tania G. Rodríguez-Cruz, Shujuan Liu, Jahan S. Khalili
PDF file, 78K, (A) Dose titration curve showing surface expression of PD-L1 on TAFs as measured by flow cytometry 18 hours following exposure to titrated doses of IL-1α or IL-1β. (B) Time course experiment assessing surface expression of PD-L1 by f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539a75a7d4825337c89225490c3f1300
https://doi.org/10.1158/1078-0432.22455606.v1
https://doi.org/10.1158/1078-0432.22455606.v1
Autor:
Gregory Lizée, Patrick Hwu, Jennifer A. Wargo, Michael A. Davies, Richard E. Davis, Laszlo G. Radvanyi, Elizabeth Grimm, Suhendan Ekmekcioglu, Chantale Bernatchez, Richard W. Joseph, Min Zhang, Yufeng Li, Dennie T. Frederick, Zachary A. Cooper, Minying Zhang, Chengwen Liu, Seth Wardell, Mayra Whittington, Tania G. Rodríguez-Cruz, Shujuan Liu, Jahan S. Khalili
PDF file, 94K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c22e6168066db15df05d0c48c9fcdd
https://doi.org/10.1158/1078-0432.22455600
https://doi.org/10.1158/1078-0432.22455600
Autor:
Gregory Lizée, Patrick Hwu, Jennifer A. Wargo, Michael A. Davies, Richard E. Davis, Laszlo G. Radvanyi, Elizabeth Grimm, Suhendan Ekmekcioglu, Chantale Bernatchez, Richard W. Joseph, Min Zhang, Yufeng Li, Dennie T. Frederick, Zachary A. Cooper, Minying Zhang, Chengwen Liu, Seth Wardell, Mayra Whittington, Tania G. Rodríguez-Cruz, Shujuan Liu, Jahan S. Khalili
PDF file, 188K, Tumor-associated fibroblasts (TAF) cultures were derived from three separate metastatic melanoma biopsies from three distinct anatomical sites: lymph node, lung and soft tissue. Cultured TAFs were exposed overnight to IL-1α, and trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d26c4974f04948c03691e731d465180
https://doi.org/10.1158/1078-0432.22455609
https://doi.org/10.1158/1078-0432.22455609