Dopamine Synthesis Capacity is Associated with D2/3 Receptor Binding but Not Dopamine Release

Autor: Berry, AS, Shah, VD, Furman, DJ, White, RL, Baker, SL, O'Neil, JP, Janabi, M, D'Esposito, M, Jagust, WJ

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 43, iss 6
Berry, AS; Shah, VD; Furman, DJ; White, RL; Baker, SL; O'Neil, JP; et al.(2018). Dopamine Synthesis Capacity is Associated with D2/3 Receptor Binding but Not Dopamine Release. Neuropsychopharmacology, 43(6), 1201-1211. doi: 10.1038/npp.2017.180. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2nr9t44c

©The Author(s) 2018. Positron Emission Tomography (PET) imaging allows the estimation of multiple aspects of dopamine function including dopamine synthesis capacity, dopamine release, and D2/3 receptor binding. Though dopaminergic dysregulation char

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Associations between [F-18]AV1451 tau PET and CSF measures of tau pathology in a clinical sample

Autor: La Joie, R, Bejanin, A, Fagan, AM, Ayakta, N, Baker, SL, Bourakova, V, Boxer, AL, Cha, J, Karydas, A, Jerome, G, Maass, A, Mensing, A, Miller, ZA, O'Neil, JP, Pham, J, Rosen, HJ, Tsai, R, Visani, AV, Miller, BL, Jagust, WJ, Rabinovici, GD

Publikováno v: La Joie, R; Bejanin, A; Fagan, AM; Ayakta, N; Baker, SL; Bourakova, V; et al.(2018). Associations between [F-18]AV1451 tau PET and CSF measures of tau pathology in a clinical sample. NEUROLOGY, 90(4), E282-+. doi: 10.1212/WNL.0000000000004860. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6wd8s9f7

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Association of cerebral amyloid-β Aggregation with cognitive functioning in persons without dementia

Autor: Jansen, WJ, Ossenkoppele, R, Tijms, BM, Fagan, AM, Hansson, O, Klunk, WE, Van Der Flier, WM, Villemagne, VL, Frisoni, GB, Fleisher, AS, Lleó, A, Mintun, MA, Wallin, A, Engelborghs, S, Na, DL, Chételat, G, Molinuevo, JL, Landau, SM, Mattsson, N, Kornhuber, J, Sabri, O, Rowe, CC, Parnetti, L, Popp, J, Fladby, T, Jagust, WJ, Aalten, P, Lee, DY, Vandenberghe, R, De Oliveira, CR, Kapaki, E, Froelich, L, Ivanoiu, A, Gabryelewicz, T, Verbeek, MM, Sanchez-Juan, P, Hildebrandt, H, Camus, V, Zboch, M, Brooks, DJ, Drzezga, A, Rinne, JO, Newberg, A, De Mendonça, A, Sarazin, M, Rabinovici, GD, Madsen, K, Kramberger, MG, Nordberg, A, Mok, V, Mroczko, B, Wolk, DA, Meyer, PT, Tsolaki, M, Scheltens, P, Verhey, FRJ, Visser, PJ, Aarsland, D, Alcolea, D, Alexander, M, Almdahl, IS, Arnold, SE, Baldeiras, I, Barthel, H, Van Berckel, BNM, Blennow, K, Van Buchem, MA, Cavedo, E, Chen, K, Chipi, E, Cohen, AD, Förster, S, Fortea, J, Frederiksen, KS, Freund-Levi, Y, Gkatzima, O, Gordon, MF, Grimmer, T, Hampel, H, Hausner, L, Hellwig, S, Herukka, SK, Johannsen, P, Klimkowicz-Mrowiec, A, Köhler, S, Koglin, N

Publikováno v: Jansen, WJ; Ossenkoppele, R; Tijms, BM; Fagan, AM; Hansson, O; Klunk, WE; et al.(2018). Association of cerebral amyloid-β Aggregation with cognitive functioning in persons without dementia. JAMA Psychiatry, 75(1), 84-95. doi: 10.1001/jamapsychiatry.2017.3391. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6rj6x6h2

IMPORTANCE Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the c

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Considerations and code for partial volume correcting [18F]-AV-1451 tau PET data

Autor: Baker, SL, Maass, A, Jagust, WJ

Publikováno v: Baker, SL; Maass, A; & Jagust, WJ. (2017). Considerations and code for partial volume correcting [18F]-AV-1451 tau PET data. Data in Brief, 15, 648-657. doi: 10.1016/j.dib.2017.10.024. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/4jb7w0n1

© 2017 The Authors [18F]-AV-1451 is a leading tracer used with positron emission tomography (PET) to quantify tau pathology. However, [18F]-AV-1451 shows “off target” or non-specific binding, which we define as binding of the tracer in unexpecte

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Amyloid and tau PET demonstrate region-specific associations in normal older people

Autor: Lockhart, SN, Schöll, M, Baker, SL, Ayakta, N, Swinnerton, KN, Bell, RK, Mellinger, TJ, Shah, VD, O'Neil, JP, Janabi, M, Jagust, WJ

Publikováno v: Lockhart, SN; Schöll, M; Baker, SL; Ayakta, N; Swinnerton, KN; Bell, RK; et al.(2017). Amyloid and tau PET demonstrate region-specific associations in normal older people. NeuroImage, 150, 191-199. doi: 10.1016/j.neuroimage.2017.02.051. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/8qg1m8v6

© 2017 Elsevier Inc. β-amyloid (Aβ) and tau pathology become increasingly prevalent with age, however, the spatial relationship between the two pathologies remains unknown. We examined local (same region) and non-local (different region) associati

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