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Akademický článek

Suppressive cancer nonstop extension mutations increase C-terminal hydrophobicity and disrupt evolutionarily conserved amino acid patterns

Autor: Avantika Ghosh, Marisa Riester, Jagriti Pal, Kadri-Ann Lainde, Carla Tangermann, Angela Wanninger, Ursula K. Dueren, Sonam Dhamija, Sven Diederichs

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Nonstop extension mutations, a.k.a. stop-lost or stop-loss mutations, convert a stop codon into a sense codon resulting in translation into the 3’ untranslated region until the next in-frame stop codon, thereby extending the C-terminus of

Externí odkaz: https://doaj.org/article/745ed8d59e844c9eb147857b617e465f

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Akademický článek

Role of Nutrition and Diet during COVID-19 pandemic: A narrative review

Autor: Jagriti Pal, Divya Sethi, Manish Taywade, Rajni Pal

Publikováno v: Journal of Family Medicine and Primary Care, Vol 11, Iss 9, Pp 4942-4948 (2022)

COVID-19 has impacted mankind drastically; whether it be physical and mental health, global economy, or social disruption, everyone has sustained losses. To prevent the spread, strict containment measures and stay at home guidelines were issued by of

Externí odkaz: https://doaj.org/article/f8c37c8aff8240299298d5fb52148d30

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Akademický článek

Noise Pollution in Intensive Care Unit: A Hidden Enemy affecting the Physical and Mental Health of Patients and Caregivers

Autor: Jagriti Pal, Manish Taywade, Rajni Pal, Divya Sethi

Publikováno v: Noise and Health, Vol 24, Iss 114, Pp 130-136 (2022)

Background Noise in intensive care units (ICUs) has always been a problem, but noise above the recommended range affects not only the patient but staff as well. It is clear that some noise in the ICU is inevitable, but exceeding the normal range brin

Externí odkaz: https://doaj.org/article/ae0ed3dc01fc4f0087df9a5c7bb02cb5

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Akademický článek

Systematic analysis of migration factors by MigExpress identifies essential cell migration control genes in non‐small cell lung cancer

Autor: Jagriti Pal, Andrea C. Becker, Sonam Dhamija, Jeanette Seiler, Mahmoud Abdelkarim, Yogita Sharma, Jürgen Behr, Chen Meng, Christina Ludwig, Bernhard Kuster, Sven Diederichs

Publikováno v: Molecular Oncology, Vol 15, Iss 7, Pp 1797-1817 (2021)

Cell migration is an essential process in health and in disease, including cancer metastasis. A comprehensive inventory of migration factors is nonetheless lacking—in part due to the difficulty in assessing migration using high‐throughput technol

Externí odkaz: https://doaj.org/article/18d11c59d43741b69d10e5882c328f36

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Akademický článek

Global RNA editome landscape discovers reduced RNA editing in glioma: loss of editing of gamma-amino butyric acid receptor alpha subunit 3 (GABRA3) favors glioma migration and invasion

Autor: Vikas Patil, Jagriti Pal, Kulandaivelu Mahalingam, Kumaravel Somasundaram

Publikováno v: PeerJ, Vol 8, p e9755 (2020)

Background Gliomas are the most common and lethal type of intracranial tumors. With the current treatment regime, the median survival of patients with grade IV glioma (glioblastoma/GBM) remains at 14–16 months. RNA editing modifies the function and

Externí odkaz: https://doaj.org/article/89b43089ad86448bbf596ff53e7c423e

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