Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jagoda Mantej"'
Autor:
Magdalena Podlacha, Lidia Gaffke, Łukasz Grabowski, Jagoda Mantej, Michał Grabski, Małgorzata Pierzchalska, Karolina Pierzynowska, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract One of the hopes for overcoming the antibiotic resistance crisis is the use of bacteriophages to combat bacterial infections, the so-called phage therapy. This therapeutic approach is generally believed to be safe for humans and animals as p
Externí odkaz:
https://doaj.org/article/df9c80bb398e4f7098d62910ccb6774c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cells exposed to stressors of various origin activate protective mechanisms that include the expression of heat shock proteins (Hsps)/molecular chaperones belonging to several families. Well-characterized inducible Hsp70 is present in all human cell-
Externí odkaz:
https://doaj.org/article/37f814b5907c4b6691563928c909d617
Autor:
Katarzyna Kosznik-Kwaśnicka, Magdalena Podlacha, Łukasz Grabowski, Małgorzata Stasiłojć, Alicja Nowak-Zaleska, Karolina Ciemińska, Zuzanna Cyske, Aleksandra Dydecka, Lidia Gaffke, Jagoda Mantej, Dorota Myślińska, Agnieszka Necel, Karolina Pierzynowska, Ewa Piotrowska, Edyta Radzanowska-Alenowicz, Estera Rintz, Krzysztof Sitko, Gracja Topka-Bielecka, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Phage therapy is a promising alternative treatment of bacterial infections in human and animals. Nevertheless, despite the appearance of many bacterial strains resistant to antibiotics, these drugs still remain important therapeutics used in human an
Externí odkaz:
https://doaj.org/article/610636f6eaa940bdaafc1decc571dca4
Autor:
Stefan Tukaj, Jagoda Mantej, Krzysztof Sitko, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Michael Kasperkiewicz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stress-induced heat shock protein 70 (Hsp70) is a key intra- and extracellular molecular chaperone implicated in autoimmune processes. Highly immunogenic extracellular Hsp70 can activate innate and acquired (adaptive) immune responses driving the gen
Externí odkaz:
https://doaj.org/article/e46f41fffa0c441487367c5d4a07bb2b
Autor:
Stefan Tukaj, Jagoda Mantej, Michał Sobala, Katarzyna Potrykus, Zbigniew Tukaj, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Michael Kasperkiewicz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Heat shock proteins (Hsp) are constitutive and stress-induced molecules which have been reported to impact innate and adaptive immune responses. Here, we evaluated the role of Hsp70 as a treatment target in the imiquimod-induced, psoriasis-like skin
Externí odkaz:
https://doaj.org/article/f36f9ab2295243c0915117cadc296a7b
Autor:
Krzysztof Sitko, Michael Kasperkiewicz, Ralf Ludwig, Marta Bednarek, Detlef Zillikens, Jagoda Mantej, Stefan Tukaj, Katja Bieber
Publikováno v:
Experimental Dermatology. 31:528-534
Heat shock protein 90 (Hsp90) and Hsp70 are chaperones implicated in different inflammatory disorders, given their property to impact innate and adaptive immune responses. Here, we determined the so far unknown role of extracellular Hsp70 in epidermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8865992022a5740bae4fe592f073ec1f
https://doi.org/10.1111/exd.14495
https://doi.org/10.1111/exd.14495
Publikováno v:
Cell Stress & Chaperones
Atopic dermatitis (AD) is one of the most common chronic inflammatory dermatoses characterized by persistent itching and recurrent eczematous lesions. While the primary events and key drivers of AD are topics of ongoing debate, cutaneous inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68aeba0ab5528938fb3928816f6abdd
https://doi.org/10.1007/s12192-021-01238-w
https://doi.org/10.1007/s12192-021-01238-w
Publikováno v:
Cell Stress & Chaperones
Extracellular heat shock proteins (Hsp) influence the adaptive immune response and may ameliorate pathogenesis of autoimmune diseases. While some preclinical observations suggest that highly conserved bacterial and/or murine Hsp70 peptides have poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6595f10eab59837d07e38c9afbb484a
https://doi.org/10.1007/s12192-020-01114-z
https://doi.org/10.1007/s12192-020-01114-z
Autor:
Lidia Gaffke, Zuzanna Szczudło, Magdalena Podlacha, Zuzanna Cyske, Estera Rintz, Jagoda Mantej, Karolina Krzelowska, Grzegorz Węgrzyn, Karolina Pierzynowska
Publikováno v:
Metabolic Brain Disease
Mucopolysaccharidoses (MPS) are a group of diseases caused by mutations resulting in deficiencies of lysosomal enzymes which lead to the accumulation of partially undegraded glycosaminoglycans (GAG). This phenomenon causes severe and chronic disturba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d18b28991f2d67bafc1ee4848c71645
https://pubmed.ncbi.nlm.nih.gov/34928474
https://pubmed.ncbi.nlm.nih.gov/34928474
Autor:
Jagoda Mantej, Karolina Pierzynowska, Grzegorz Węgrzyn, Dorota Myślińska, Magdalena Podlacha, I. Majkutewicz, Lidia Gaffke, Marta Osiadły, Alicja Węgrzyn
Publikováno v:
Neuropharmacology. 148:332-346
Alzheimer's disease is one of severe neurological diseases for which no effective treatment is currently available. The use of genistein (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) has been proposed previously as one of approaches to im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3b75bb23e2f846485ca67fc7981cce
https://doi.org/10.1016/j.neuropharm.2019.01.030
https://doi.org/10.1016/j.neuropharm.2019.01.030