Engineering of chimeric enzymes with expanded tolerance to ionic strength.

Autor: Mitkowski P; International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.; Mossakowski Medical Research Institute Polish Academy of Sciences, Warsaw, Poland., Jagielska E; International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.; Mossakowski Medical Research Institute Polish Academy of Sciences, Warsaw, Poland., Sabała I; International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.; Mossakowski Medical Research Institute Polish Academy of Sciences, Warsaw, Poland.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2024 Jun 04; Vol. 12 (6), pp. e0354623. Date of Electronic Publication: 2024 May 02.

Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b

Autor: Gonzalez-Delgado, L.S., Walters-Morgan, H., Salamaga, B., Robertson, A.J., Hounslow, A.M., Jagielska, E., Sabała, I., Williamson, M.P., Lovering, A.L., Mesnage, S.

Lysostaphin is a bacteriolytic enzyme targeting peptidoglycan, the essential component of the bacterial cell envelope. It displays a very potent and specific activity toward staphylococci, including methicillin-resistant Staphylococcus aureus. Lysost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::924fb9b0f6aa05cbf5cb6afdac390a07

Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b.

Autor: Gonzalez-Delgado LS; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.; Krebs Institute, University of Sheffield, Sheffield, UK., Walters-Morgan H; Institute of Microbiology and Infection, and School of Biosciences, University of Birmingham, Birmingham, UK., Salamaga B; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.; Krebs Institute, University of Sheffield, Sheffield, UK., Robertson AJ; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.; Krebs Institute, University of Sheffield, Sheffield, UK., Hounslow AM; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.; Krebs Institute, University of Sheffield, Sheffield, UK., Jagielska E; International Institute of Molecular and Cell Biology, Warsaw, Poland., Sabała I; International Institute of Molecular and Cell Biology, Warsaw, Poland., Williamson MP; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK. m.williamson@sheffield.ac.uk.; Krebs Institute, University of Sheffield, Sheffield, UK. m.williamson@sheffield.ac.uk., Lovering AL; Institute of Microbiology and Infection, and School of Biosciences, University of Birmingham, Birmingham, UK. a.lovering@bham.ac.uk., Mesnage S; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK. s.mesnage@sheffield.ac.uk.; Krebs Institute, University of Sheffield, Sheffield, UK. s.mesnage@sheffield.ac.uk.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2020 Jan; Vol. 16 (1), pp. 24-30. Date of Electronic Publication: 2019 Nov 04.

Structural Characterization of EnpA D,L-Endopeptidase from Enterococcus faecalis Prophage Provides Insights into Substrate Specificity of M23 Peptidases.

Autor: Małecki PH; International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland., Mitkowski P; International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland., Jagielska E; International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland., Trochimiak K; International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland., Mesnage S; Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, UK., Sabała I; International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 01; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 01.

Characterization and bioinformatic analysis of a new chimeric endolysin against MRSA with great stability.

Autor: Momen, Sanaz¹ (AUTHOR), Soleimani, Neda¹ (AUTHOR), Azizmohseni, Farzaneh² (AUTHOR), Ahmadbeigi, Yasaman¹ (AUTHOR), Borhani, Seddigheh³ (AUTHOR), Amini-Bayat, Zahra² (AUTHOR) Amini-bayat@irost.org

Publikováno v: AMB Express. 12/26/2024, Vol. 14 Issue 1, p1-12. 12p.