Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jagdev, Sidhu"'
Autor:
Denis Menshykau, Jagdev Sidhu, Laura Shaughnessy, Rocio Lledo‐Garcia, Pinky Dua, Marie Teil, Akash Khandelwal
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 11, Pp 1904-1914 (2024)
Abstract Certolizumab pegol (CZP; CIMZIA™) is the only Fc‐free tumor necrosis factor inhibitor with data from a clinical study demonstrating no to minimal placental transfer. The pharmacokinetics (PK) of certolizumab pegol during pregnancy and po
Externí odkaz:
https://doaj.org/article/0ea6f96c831248acb8c94d0a71f46dd0
Autor:
Christian Wolf, Jagdev Sidhu, Christian Otoul, Dexter L Morris, Jennifer Cnops, Jorg Taubel, Barbara Bennett
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58438 (2013)
Lymphocyte inhibition by antagonism of α4 integrins is a validated therapeutic approach for relapsing multiple sclerosis (RMS).Investigate the effect of CDP323, an oral α4-integrin inhibitor, on lymphocyte biomarkers in RMS.Seventy-one RMS subjects
Externí odkaz:
https://doaj.org/article/51d60e745c2a4d8fa251d479697ccc5e
Publikováno v:
British Journal of Clinical Pharmacology. 61:191-199
Aims To assess the pharmacokinetic and pharmacodynamic effects of co-administration of a combined oral contraceptive (ethinyloestradiol plus levonorgestrel) and lamotrigine. Methods Over a period of 130 days, healthy female subjects took lamotrigine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6937c1525c273e96127b3570697b63
https://doi.org/10.1111/j.1365-2125.2005.02539.x
https://doi.org/10.1111/j.1365-2125.2005.02539.x
Autor:
Sarah Job, Jonathan Bullman, John A. Ascher, Jagdev Sidhu, Richard Abbott, Emma Francis, Jochen G W Theis
Publikováno v:
British Journal of Clinical Pharmacology. 61:420-426
Aim To assess the pharmacokinetic effect and tolerability of lamotrigine 200 mg day−1 and olanzapine 15 mg day−1 coadministration in healthy male volunteers. Methods Subjects were randomized to receive either lamotrigine titrated on days 1–42 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3660e5fa4a00a6f9b684650ff3c8df7
https://doi.org/10.1111/j.1365-2125.2006.02598.x
https://doi.org/10.1111/j.1365-2125.2006.02598.x
Publikováno v:
Neuropsychopharmacology. 30:2269-2274
Epilepsy and bipolar disorder are commonly treated by combination drug therapy, such as lamotrigine and oxcarbazepine. To ensure the safety of this combination, information on pharmacokinetics and tolerability must be available. The objective of stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967c508a7eb8e3f4ce3f6972a140e54b
https://doi.org/10.1038/sj.npp.1300831
https://doi.org/10.1038/sj.npp.1300831
Autor:
Jagdev Sidhu, Alain Segonzac, Frank Larsen, Gilles Grollier, Morten Priskorn, Mette Nøhr Poulsen
Publikováno v:
Chirality. 9:686-692
The steady-state pharmacokinetics in serum and urine of the enantiomers of citalopram and its metabolites, demethylcitalopram (DCT) and didemethylcitalopram (DDCT), were investigated after multiple doses of rac-citalopram for 21 consecutive days (40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62549fde7eec78e4d6a288b65cd0e766
https://doi.org/10.1002/(sici)1520-636x(1997)9:7<686::aid-chir9>3.0.co
https://doi.org/10.1002/(sici)1520-636x(1997)9:7<686::aid-chir9>3.0.co
Autor:
Jagdev, Sidhu, Sarah, Job, Jonathan, Bullman, Emma, Francis, Richard, Abbott, John, Ascher, Jochen G W, Theis
Publikováno v:
British journal of clinical pharmacology. 61(4)
To assess the pharmacokinetic effect and tolerability of lamotrigine 200 mg day(-1) and olanzapine 15 mg day(-1) coadministration in healthy male volunteers.Subjects were randomized to receive either lamotrigine titrated on days 1-42 with olanzapine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30fb7d318c3e784111904fcccedea956
https://pubmed.ncbi.nlm.nih.gov/16542203
https://pubmed.ncbi.nlm.nih.gov/16542203
Autor:
Anastasia Lewis, Jagdev Sidhu, Simon John Summers, Diane Boswell, Christine Walls, Alan W. Dow, Jonathan Bullman
Publikováno v:
Current medical research and opinion. 20(6)
Rapid delivery of migraine-specific medication to its site(s) of action is thought to be crucial in preventing or minimizing sensitization of central pain pathways and thereby in optimizing pain-free outcomes in patients with migraine. Sumatriptan ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4b938ac68a4382590b17c447020eb7
https://pubmed.ncbi.nlm.nih.gov/15200736
https://pubmed.ncbi.nlm.nih.gov/15200736
Publikováno v:
The Journal of Pain. 6:S83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6101d215843dc250be3ffa2203366f8f
https://doi.org/10.1016/j.jpain.2005.01.329
https://doi.org/10.1016/j.jpain.2005.01.329
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P22
Background LTG and OXC may be coadministered during the treatment of epilepsy or bipolar disorder. In vitro, OXC and its active 10–monohydroxy metabolite (MHD) are weak inducers of UDP-glucuronyl transferase, which may increase LTG conjugation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3b5b70484a72e779b663f8dee8867d8
https://doi.org/10.1016/j.clpt.2003.11.082
https://doi.org/10.1016/j.clpt.2003.11.082