Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jagdeep Grover"'
Autor:
Aurore Guédin, Stefan Bernhard, Mathias O. Senge, Isabel Rozas, Ganapathi Emandi, Jagdeep Grover, Jean-Louis Mergny, Cristina Trujillo, Mona Saad, Nikolina Stipaničev
Publikováno v:
Organic & Biomolecular Chemistry. 18:5617-5624
The first conceptualised class of dual-binding guanine quadruplex binders has been designed, synthesised and biophysically studied. These compounds combine diaromatic guanidinium systems and neutral tetra-phenylporphyrins (classical binding moiety fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0533763394b290b1df63e8ef995b424f
https://doi.org/10.1039/d0ob01264e
https://doi.org/10.1039/d0ob01264e
Publikováno v:
ACS Catalysis. 8:2748-2753
We present the details of an organophosphine-catalyzed Morita–Baylis–Hillman-type reaction of activated alkynes. The outcome is an intramolecular hydroacylation of α,β-ynones leading to the formation of 1,3-cyclopenta-, cyclohepta-, and cyclooc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::120151054b54eb499c7c5d632d84e1fd
https://doi.org/10.1021/acscatal.8b00397
https://doi.org/10.1021/acscatal.8b00397
Publikováno v:
Synthesis. 50:1462-1470
An efficient organocatalytic approach for the cyclopenta[b]annulation of benzothiophenes via γ′[C(sp3)–H] functionalization of ynones is described. Nucleophilic addition of an organophosphine to the designed ynones generates heteroaryl-based ort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::270d1cfe3661778b9c92c36a94487bd3
https://doi.org/10.1055/s-0036-1591526
https://doi.org/10.1055/s-0036-1591526
Publikováno v:
Chemistry - A European Journal. 22:18316-18321
A new approach for the cyclopenta[b]annulation of heteroarenes through metal-free and directing-group-free γ'[C(sp3 )-H] functionalization and intramolecular hydroalkylation of ynones has been developed. In an unprecedented event, nucleophilic addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8160b70601fe0ab1a3a05ab0d4e978e2
https://doi.org/10.1002/chem.201604562
https://doi.org/10.1002/chem.201604562
Publikováno v:
Journal of Analytical Chemistry. 70:639-646
Negundoside and agnuside are reported as marker constituents for standardization of Vitex negundo (V. negundo) leaves. This is the first report on determination and quantification of negundoside and agnuside by qNMR in the leaves of V. negundo, colle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e75240ce308d1b7735de6b7c31f8fb
https://doi.org/10.1134/s1061934815050147
https://doi.org/10.1134/s1061934815050147
Autor:
Sanjay M. Jachak, Vivek Kumar, Bhagirath J. Gondaliya, M. Elizabeth Sobhia, Jagdeep Grover, Neeraj K. Patel, Nirav Bhatt, Kamlesh K. Bhutani
Publikováno v:
RSC Advances. 5:45535-45544
A new series of compounds comprising of 2,5-diaryl-1,3,4-oxadiazoles was synthesized and evaluated as potential COX-2 inhibitors. Compounds 6b, 6e, 6f, 7e and 7f were found to be the most potent and selective inhibitors of COX-2 (IC50 = 0.48–0.89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a922091ca2d89d911ecc69097193ecc
https://doi.org/10.1039/c5ra01428j
https://doi.org/10.1039/c5ra01428j
Publikováno v:
Журнал аналитической химии. 70:550-557
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::523594373d33bd778dac750b86a75dba
https://doi.org/10.7868/s0044450215050151
https://doi.org/10.7868/s0044450215050151
Autor:
Sanjay M. Jachak, Jagdeep Grover
Publikováno v:
RSC Advances. 5:38892-38905
Several literature reports had highlighted the significance of coumarin nucleus as a source of potential candidates for anti-inflammatory drug development. Various natural coumarins such as umbelliferone, scopoletin, visnadin, marmin and esculetin de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ed34ca012273cd9b4bd56a98ffed6a
https://doi.org/10.1039/c5ra05643h
https://doi.org/10.1039/c5ra05643h
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:4638-4642
As a part of our continued efforts to discover new COX inhibitors, a series of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones were synthesized and evaluated for in vitro COX inhibitory potential. Within this series, seven compounds (3a–d, 3h, 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b1ad5a576a4d5b31f2d34e0913db18
https://doi.org/10.1016/j.bmcl.2014.08.050
https://doi.org/10.1016/j.bmcl.2014.08.050
Publikováno v:
Synthetic Communications. 44:1914-1923
Unprecedented cyclization was observed during N-sulfonylation of 3-[1-(phenylhydrazono)-ethyl]-chromen-2-one in pyridine, affording 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones. To avoid use of noxious pyridine, reaction was tried in different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d0af3c33245b64765f10cd1c0a65cb
https://doi.org/10.1080/00397911.2013.879184
https://doi.org/10.1080/00397911.2013.879184