Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jagarlapudi A. R. P. Sarma"'
Autor:
Hosahalli S. Subramanya, Jagarlapudi A. R. P. Sarma, Dayam Raveendra, Ram K. R. Jetti, Bulusu Gopalakrishnan, Gautam R. Desiraju
Publikováno v:
Molecules, Vol 5, Iss 7, Pp 945-955 (2000)
Selective cyclooxygenase inhibitors have attracted much attention in recent times in the design of new non-steroidal anti-inflammatory drugs (NSAID). 3D-QSAR studies have been performed on a series of 1,5-diarylpyrazoles that act as selective cycloox
Externí odkaz:
https://doaj.org/article/7d290ebffa8d4e6c96a72ecd774225b9
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 12, Pp o2411-o2411 (2008)
In the crystal structure of the title compound, 2C5H5N4O+·SO42−, N—H...O hydrogen bonds assemble the molecules into a two-dimensional network structure parallel to the cb plane. The S atom of the sulfate ion lies on a special position on a twofo
Externí odkaz:
https://doaj.org/article/11673f9e3f5246f6aa72583818b08ed7
Autor:
Shili Xu, Lakshmi Narasu, Nouri Neamati, Raveendra Dayam, Jagarlapudi A. R. P. Sarma, Sardar Shamshair Singh
Publikováno v:
Current Topics in Medicinal Chemistry. 14:2020-2030
A tremendous research on Poly (ADP-ribose) polymerase (PARP) pertaining to cancer and ischemia is in very rapid progress. PARP's are a specific class of enzymes that repairs the damaged DNA. Recent findings suggest also that PARP-1 is the most abunda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a835ecfa1eed2ae6b8bc63d50740464
https://doi.org/10.2174/1568026614666140929152123
https://doi.org/10.2174/1568026614666140929152123
Autor:
Raveendra Dayam, Jyoti Roy, Rambabu Gundla, Jagarlapudi A. R. P. Sarma, Uday Chandra Kumar, Pavan Kumar Machiraju, Suneel Kumar B.V.S, Ravi Kumar Muttineni
Publikováno v:
Journal of Molecular Graphics and Modelling. 29:256-265
Bacillus anthracis is a causative organism of anthrax. The main reason to use anthrax as a bioweapon is the combination of the spore's durability and the lethal toxaemia of the vegetative stage. In anthrax infection, lethal factor (LF) is playing cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d4061235331bed9dbf0be4de3f693e
https://doi.org/10.1016/j.jmgm.2010.07.002
https://doi.org/10.1016/j.jmgm.2010.07.002
Autor:
Jyoti Roy, Rohith Kotla, B.V.S. Suneel Kumar, Rambabu Gundla, Muttineni Ravikumar, Jagarlapudi A. R. P. Sarma, Revanth Buddiga, Sardar Shamshair Singh
Publikováno v:
Journal of Molecular Modeling. 17:151-163
Structure and ligand based pharmacophore modeling and docking studies carried out using diversified set of c-Jun N-terminal kinase-3 (JNK3) inhibitors are presented in this paper. Ligand based pharmacophore model (LBPM) was developed for 106 inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1348bf62a3e28e864a31d0c58b931e6
https://doi.org/10.1007/s00894-010-0701-0
https://doi.org/10.1007/s00894-010-0701-0
Autor:
Nouri Neamati, Jagarlapudi A. R. P. Sarma, Raveendra Dayam, Ramadevi Sanam, Ravikumar Muttineni, Roza Kazemi, Rambabu Gundla
Publikováno v:
Journal of Medicinal Chemistry. 51:3367-3377
Consensus virtual screening models were generated and validated utilizing a set of known human epidermal growth factor receptor-2 (HER2) inhibitors and modeled HER2 active and inactive state structures. The virtual screening models were successfully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492fb472fc163a28bcb22f7753aaf412
https://doi.org/10.1021/jm7013875
https://doi.org/10.1021/jm7013875
Publikováno v:
physica status solidi (a). 204:3454-3462
Rhombohedral Nasicon type materials of composition Ag3–2xTax Al2–x(PO4)3 (x = 0.6, 0.7,0.8, 0.9, 1.0, 1.1,1.2, 1.3 and 1.4) have been prepared and characterized by powder XRD and IR. All these compositions are found to be isomorphous with NbTiP3O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56062680e9ea43634b8ed038b35f7b8c
https://doi.org/10.1002/pssa.200622425
https://doi.org/10.1002/pssa.200622425
Autor:
L. Sreenivas Reddy, Gautam R. Desiraju, Roland Boese, Peddy Vishweshwar, Jagarlapudi A. R. P. Sarma, Ram K. R. Jetti
Publikováno v:
Angewandte Chemie. 115:2008-2012
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::523c6b3405058128eddaf1145ef8ebf9
https://doi.org/10.1002/ange.200250660
https://doi.org/10.1002/ange.200250660
Publikováno v:
Drug Design and Discovery. 18:47-51
Thromboxane A2receptor antagonists have attracted much attention in recent times in the design of new agents that could be active against diseases such as thrombosis, asthma and myocardial ischemia. 3D-QSAR studies have been performed on a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8655e0fb7a45bb964e6f1abf5ab852
https://doi.org/10.3109/10559610290252869
https://doi.org/10.3109/10559610290252869
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2689-2693
3D-QSAR studies using MFA and RSA methods were performed on a series of 39MMP-13 inhibitors. Model developed by MFA method has a r(2)(cv) (cross-validated) of 0.616 while its r(2) (conventional) value is 0.822. For the RSA model r(2)(cv) and r(2) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bbdb97db28e136bd440f33969af411
https://doi.org/10.1016/s0960-894x(02)00559-0
https://doi.org/10.1016/s0960-894x(02)00559-0