Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jagannath Misra"'
Autor:
Ricardo A Cordova, Jagannath Misra, Parth H Amin, Anglea J Klunk, Nur P Damayanti, Kenneth R Carlson, Andrew J Elmendorf, Hyeong-Geug Kim, Emily T Mirek, Bennet D Elzey, Marcus J Miller, X Charlie Dong, Liang Cheng, Tracy G Anthony, Roberto Pili, Ronald C Wek, Kirk A Staschke
Publikováno v:
eLife, Vol 11 (2022)
A stress adaptation pathway termed the integrated stress response has been suggested to be active in many cancers including prostate cancer (PCa). Here, we demonstrate that the eIF2 kinase GCN2 is required for sustained growth in androgen-sensitive a
Externí odkaz:
https://doaj.org/article/0e190e2bb8b949968cf1c2d48ee6413b
Autor:
Jagannath Misra, Dipanjan Chanda, Don-Kyu Kim, Seung-Rye Cho, Seung-Hoi Koo, Chul-Ho Lee, Sung Hoon Back, Hueng-Sik Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86342 (2014)
The orphan nuclear receptor estrogen-related receptor-γ (ERRγ) is a constitutively active transcription factor regulating genes involved in several important cellular processes, including hepatic glucose metabolism, alcohol metabolism, and the endo
Externí odkaz:
https://doaj.org/article/b8eb593143c049fd9032f747bc172045
Autor:
Dipanjan Chanda, Yong-Hoon Kim, Tiangang Li, Jagannath Misra, Don-Kyu Kim, Jung Ran Kim, Joseph Kwon, Won-Il Jeong, Sung-Hoon Ahn, Tae-Sik Park, Seung-Hoi Koo, John Y L Chiang, Chul-Ho Lee, Hueng-Sik Choi
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68845 (2013)
Bile acids concentration in liver is tightly regulated to prevent cell damage. Previous studies have demonstrated that deregulation of bile acid homeostasis can lead to cholestatic liver disease. Recently, we have shown that ER-bound transcription fa
Externí odkaz:
https://doaj.org/article/bbd54b9e0aa64dd0b96b06b9da7d7b41
Autor:
Sankalp Srivastava, Jie Jiang, Gretchen Seim, Jagannath Misra, Utpal Dave, Reuben Kapur, Jiehao Zhou, Jing Fan, Ronald Wek, Ji Zhang
Publikováno v:
Blood. 140:3040-3041
Autor:
Michael Langevin, Malcolm Watford, Jagannath Misra, Michael J. Holmes, Tracy G. Anthony, Kenneth R Carlson, Ronald C. Wek, Emily T. Mirek, X. Charlie Dong, Hyeong-Geug Kim
Publikováno v:
Nucleic Acids Research
Appropriate regulation of the Integrated stress response (ISR) and mTORC1 signaling are central for cell adaptation to starvation for amino acids. Halofuginone (HF) is a potent inhibitor of aminoacylation of tRNAPro with broad biomedical applications
Autor:
Ricardo Cordova, Jagannath Misra, Parth H. Amin, Nur P. Damayanti, Kenneth R. Carlson, Angela J. Klunk, Emily T. Mirek, Marcus J. Miller, Tracy G. Anthony, Roberto Pili, Ronald C. Wek, Kirk A. Staschke
Publikováno v:
The FASEB Journal. 36
Autor:
Sankalp Srivastava, Jie Jiang, Jagannath Misra, Gretchen Seim, Kirk A. Staschke, Minghua Zhong, Leonardo Zhou, Yu Liu, Chong Chen, Utpal Davé, Reuben Kapur, Sandeep Batra, Chi Zhang, Jiehao Zhou, Jing Fan, Ronald C. Wek, Ji Zhang
Publikováno v:
Oncogene
Amino acid restriction has recently emerged as a compelling strategy to inhibit tumor growth. Recent work suggests that amino acids can regulate cellular signaling in addition to their role as biosynthetic substrates. Using lymphoid cancer cells as a
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2428
Translational control provides a strategy for rapid optimization of gene expression and restoration of protein homeostasis in response to cellular stresses. An important mechanism for translational control involves phosphorylation of eIF2, which invo
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68c9bee9b33beeb7c893559fe88ce899
https://doi.org/10.1007/978-1-0716-1975-9_10
https://doi.org/10.1007/978-1-0716-1975-9_10
Autor:
Ricardo Cordova, Jagannath Misra, Nur P. Damayanti, Parth H. Amin, Kenneth R. Carlson, Angela J. Klunk, Emily T. Mirek, Marcus J. Miller, Tracy G. Anthony, Roberto Pili, Ronald C. Wek, Kirk A. Staschke
Publikováno v:
Cancer Research. 82:3040-3040
The Integrated Stress Response (ISR) is central for adaptation and survival of tumor cells in response to exogenous and endogenous stresses. The ISR features a family of protein kinases that phosphorylate the eukaryotic translation initiation factor