Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jaganathan Venkatesh"'
Autor:
Jaganathan Venkatesh, Magesh Muthu, Indulekha Singaravelu, Vino T. Cheriyan, Sreeja C. Sekhar, Nuwan C. P. N. Acharige, Edi Levi, Hadeel Assad, Mary Kay H. Pflum, Arun K. Rishi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
CARP-1, a perinuclear phospho-protein, regulates cell survival and apoptosis signaling induced by genotoxic drugs. However, kinase(s) phosphorylating CARP-1 and down-stream signal transduction events remain unclear. Here we find that CARP-1 Serine (S
Externí odkaz:
https://doaj.org/article/b16e0fa2d7b74d1285d89bd2f8c2e8b6
Autor:
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 91-112 (2024)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes. To investigate the mechanism of ALDH1A3‐med
Externí odkaz:
https://doaj.org/article/3963ad169532432cb23f181c5b3a6969
Autor:
Marie-Claire D Wasson, Justin M Brown, Jaganathan Venkatesh, Wasundara Fernando, Paola Marcato
Publikováno v:
Data in Brief, Vol 37, Iss , Pp 107241- (2021)
Long non-coding RNA (lncRNA)/microRNA (miRNA)/messenger RNA (mRNA) interactions regulate oncogenesis and tumour suppression in breast cancer. Oncogenic lncRNA/miRNA/mRNA axes may offer novel therapeutic targets; therefore, identifying such axes is a
Externí odkaz:
https://doaj.org/article/62abb62831064c688355a0f639a3a4f1
Publikováno v:
Methods in cell biology. 171
The heterogeneity of breast tumors is a major factor in the development, progression, and therapeutic response of breast cancer. In terms of therapy resistance, a subset of tumor cells commonly referred to as cancer stem cells (CSCs) or tumor initiat
Publikováno v:
Cancer Research. 83:3737-3737
CARP-1, a perinuclear phospho-protein, is a biphasic regulator of cell survival and apoptosis signaling. Genotoxic drugs induce apoptosis in part by elevating CARP-1 levels while also promote cell survival in part by activating NF-κB that involves C
Publikováno v:
Cancer Research. 83:3738-3738
CARP-1, a perinuclear phospho-protein, is a biphasic regulator of cell survival and apoptosis signaling induced by genotoxic drugs. We have previously found that apoptosis induced by genotoxic drugs involved elevated levels of CARP-1. Exposure to gen
Autor:
Jaganathan Venkatesh, Arun K. Rishi, Lisa Polin, Sijana H. Dzinic, Edi Levi, James W. Gauld, Paul Meister, Vino T. Cheriyan, Magesh Muthu, Sreeja C. Sekhar
Publikováno v:
J Biol Chem
NF-κB is a pro-inflammatory transcription factor that critically regulates immune responses and other distinct cellular pathways. However, many NF-κB–mediated pathways for cell survival and apoptosis signaling in cancer remain to be elucidated. C
Publikováno v:
Methods in Cell Biology ISBN: 9780323900188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e96cfba0321172b8a372cf91e11a680
https://doi.org/10.1016/bs.mcb.2022.04.006
https://doi.org/10.1016/bs.mcb.2022.04.006
Autor:
Meghan E. McLean, Maya R. MacLean, Hannah F. Cahill, Raj Pranap Arun, Olivia L. Walker, Marie-Claire D. Wasson, Wasundara Fernando, Jaganathan Venkatesh, Paola Marcato
Publikováno v:
Cancers. 15:492
Aldehyde dehydrogenase 1A3 (ALDH1A3) is one of 19 ALDH enzymes expressed in humans, and it is critical in the production of hormone receptor ligand retinoic acid (RA). We review the role of ALDH1A3 in normal physiology, its identification as a cancer
Autor:
Olivia L Walker, Justin M Brown, Cheryl A. Dean, Wasundara Fernando, Paola Marcato, Graham Dellaire, Brianne M. Cruickshank, Margaret L. Dahn, Marie-Claire D Wasson, Dejan Vidovic, Carter VanIderstine, Fiorella Morales-Quintanilla, Jaganathan Venkatesh
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Triple-negative breast cancers (TNBCs) are aggressive, lack targeted therapies and are enriched in cancer stem cells (CSCs). Novel therapies which target CSCs within these tumors would likely lead to improved outcomes for TNBC patients. Long non-codi