Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jagan Sundaram"'
Autor:
Shiva Keshava, Jagan Sundaram, Anuradha Rajulapati, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1206-1214 (2017)
Abstract: Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of recombinant FVIIa (rFVIIa) in ther
Externí odkaz:
https://doaj.org/article/414c43275e3f4e399e2a807b14913bcc
Publikováno v:
Journal of Colloid and Interface Science. 628:820-828
Undesired aggregation and adsorption of therapeutic proteins during manufacturing and administration processes can significantly decrease the efficacy of protein drugs, especially when a quantitative treatment is critical. In this study, we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c948d947b8102e98fefcaa3c44ccff4
https://doi.org/10.1016/j.jcis.2022.07.161
https://doi.org/10.1016/j.jcis.2022.07.161
Autor:
Ashok Mari, Nirmala Subramaniam, Palanisamy Krishnan, Pugazhendhi Kannan, Devaki Thiruvengadam, Gopalakrishnan Balaraman, Sharmila Salam, Jagan Sundaram, Sathesh Kanna Velli
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 21:2546-2552
Background: To evaluate the chemopreventive potential of boldine against diethylnitrosamine (DEN) induced hepatocellular carcinoma (HCC) in wistar albino rats. Objective: Boldine is an alkaloid isolated from Peumus boldus. The primary active constitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0810cbdaa31bf0664b06e08479d7a556
https://doi.org/10.2174/1871520621666210203102854
https://doi.org/10.2174/1871520621666210203102854
Autor:
Palanisamy Krishnan, Ashok Mari, Nirmala Subramaniam, Immaduddin Sirajduddin, Sharmila Salam, Jagan Sundaram, Gopalakrishnan Balaraman, Devaki Thiruvengadam
Publikováno v:
Environmental Toxicology. 36:2467-2474
Hepatocellular carcinoma is a well-known internal malignancy with increased worldwide mortality. The increased progression rate is closely associated with chronic liver diseases such as cirrhosis. Chemical carcinogens cause tumor advocacy over free r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eed95f6630f7a8e9916ee135f2ba43
https://doi.org/10.1002/tox.23359
https://doi.org/10.1002/tox.23359
Autor:
Raghunandhakumar, Subramanian, Paramasivam, Arumugam, Senthilraja, Selvam, Naveenkumar, Chandrasekar, Asokkumar, Selvamani, Binuclara, John, Jagan, Sundaram, Anandakumar, Pandi, Devaki, Thiruvengadam
Publikováno v:
In Toxicology Letters 23 October 2013 223(1):60-72
Autor:
Jagan Sundaram, Nirmala Subramanian, Gopalakrishnan Balaraman, Fathima Bushra Mirza, Ashok Mari, Devaki Thiruvengadam, Sirpu Natesh Nagabhishek, Gopikrishnan Mani
Publikováno v:
Chinese Journal of Integrative Medicine. 27:680-687
To examine the role of carvacrol in modulating PI3K/AKT signaling involved in human breast cancer pathogenesis using in vitro experimental model MCF-7 cells. MTT and lactate dehydrogenase assays were performed with cells treated with different doses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6302a1788925b32b6fd9a104d1d1d
https://doi.org/10.1007/s11655-020-3193-5
https://doi.org/10.1007/s11655-020-3193-5
Autor:
Kamaraj, Sattu, Anandakumar, Pandi, Jagan, Sundaram, Ramakrishnan, Gopalakrishnan, Devaki, Thiruvengadam
Publikováno v:
In European Journal of Pharmacology 2010 649(1):320-327
Autor:
Anuradha Rajulapati, Usha R. Pendurthi, Shiva Keshava, Jagan Sundaram, Charles T. Esmon, L. Vijaya Mohan Rao
Publikováno v:
Blood Advances. 1:1206-1214
Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of recombinant FVIIa (rFVIIa) in therapeutic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121228e6e375f0107ed92f316eb811cb
https://doi.org/10.1182/bloodadvances.2016004143
https://doi.org/10.1182/bloodadvances.2016004143
Autor:
Devaki Thiruvengadam, Manikandan Murugan, Gopalakrishnan Balaraman, Jagan Sundaram, Sathesh Kanna Velli
Publikováno v:
Journal of biochemical and molecular toxicology. 33(10)
Vanillic acid (VA) is found in high concentrations in various plants and used as traditional medicine for various diseases. The aim of the existing study is to illustrate the protective effects of VA against benzo(a)pyrene (B(a)P)-induced lung cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc611fe9c7bd99d33c106c69065d1be2
https://pubmed.ncbi.nlm.nih.gov/31468657
https://pubmed.ncbi.nlm.nih.gov/31468657
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 14(3)
UNLABELLED ESSENTIALS: The role of tissue factor (TF) in recombinant factor VIIa (rFVIIa) therapy in hemophilia is unclear. An acquired mouse hemophilia model with very low or normal levels of human TF was used in the study. rFVIIa is equally effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eac89743ca37ce5b72ad29847037877
https://pubmed.ncbi.nlm.nih.gov/26727350
https://pubmed.ncbi.nlm.nih.gov/26727350