Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jagadish Koya"'
Autor:
Zi-Ning Lei, Qiu-Xu Teng, Jagadish Koya, Yangruiyu Liu, Zizhou Chen, Leli Zeng, Zhe-Sheng Chen, Shuo Fang, Jinxiang Wang, Yuchen Liu, Yihang Pan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The connections between cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) is critical in cancer initiation, progression, metastasis, and therapy resistance, making it a focal point in cancer theragnosis. This review provides a pano
Externí odkaz:
https://doaj.org/article/5784f6a00ca34347ae90a9969e0abcd1
Autor:
Zeng-Hui Wei, Jagadish Koya, Nikita Acharekar, Jesus Trejos, Xing-Duo Dong, Francis A. Schanne, Charles R. Ashby, Sandra E. Reznik
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Alzheimer’s disease (AD) is a chronic degenerative brain disorder with no clear pathogenesis or effective cure, accounting for 60–80% of cases of dementia. In recent years, the importance of neuroinflammation in the pathogenesis of AD an
Externí odkaz:
https://doaj.org/article/893fcb60e9304622ad9b4df38e80801f
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer disease (AD) is a chronic neurodegenerative disease that accounts for 60–70% of dementia and is the sixth leading cause of death in the United States. The pathogenesis of this debilitating disorder is still not completely understood. New
Externí odkaz:
https://doaj.org/article/65d8bee983c94c2fa01da64a0c1a31e0
Autor:
Zeng-Hui Wei, Oluwabukola O. Salami, Jagadish Koya, Swapna Munnangi, Ryan Pekson, Charles R. Ashby, Sandra E. Reznik
Publikováno v:
Reproductive Sciences. 29:2894-2907
Autor:
Zhe-Sheng Chen, Silpa Narayanan, Hansu Ma, Zhuo-Xun Wu, Sabesan Yoganathan, Shuo Fang, Yihang Pan, Jing-Quan Wang, Jagadish Koya, Nikita Acharekar
Publikováno v:
International Journal of Biological Sciences
Tyrosine kinase inhibitors (TKIs) are important in managing lymphoid malignancies by targeting B-cell receptor signaling pathways. Entospletinib (GS-9973) is an oral, selective inhibitor of spleen tyrosine kinase (Syk), currently in the phase II clin
Autor:
Zeng-Hui, Wei, Oluwabukola O, Salami, Jagadish, Koya, Swapna, Munnangi, Ryan, Pekson, Charles R, Ashby, Sandra E, Reznik
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 29(10)
Preterm birth accounts for the majority of perinatal mortality worldwide, and there remains no FDA-approved drug to prevent it. Recently, we discovered that the common drug excipient, N,N-dimethylacetamide (DMA), delays inflammation-induced preterm b
Autor:
Zeng-Hui Wei, Oluwabukola Salami, Jagadish Koya, Swapna Munnangi, Ryan Pekson, Charles R. Ashby, Sandra Reznik
Preterm birth accounts for the majority of perinatal mortality worldwide and there remains no FDA-approved drug to prevent it. Recently, we discovered that the common drug excipient, N,N-dimethylacetamide (DMA), prevents inflammation–induced preter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ee7ca57d33ceebfed273963e3762856
https://doi.org/10.21203/rs.3.rs-969393/v1
https://doi.org/10.21203/rs.3.rs-969393/v1
Autor:
Tong Shen, Geming Lu, Lin L. Mantell, Charles R. Ashby, Jagadish Koya, Alex G. Gauthier, Sandra E. Reznik
Inflammatory bowel disease (IBD) affects almost 7 million people worldwide and is increasing in incidence. While the precise pathogenesis of IBD remains unknown, the production of inflammatory cytokines and chemokines play a central role. We have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2001d4f2d282f9ecc7983144fdb20e
https://doi.org/10.21203/rs.3.rs-948100/v1
https://doi.org/10.21203/rs.3.rs-948100/v1
Autor:
Sandra E. Reznik, Geming Lu, Lin L. Mantell, Tong Shen, Alex G. Gauthier, Jagadish Koya, Charles R. Ashby
Background: Inflammatory bowel disease (IBD) affects almost 7 million people worldwide and is increasing in incidence. While the precise pathogenesis of IBD remains unknown, the production of inflammatory cytokines and chemokines play a central role.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb73752ea1af8427bb6ea68a92ad06b
https://doi.org/10.21203/rs.3.rs-864635/v1
https://doi.org/10.21203/rs.3.rs-864635/v1
Autor:
Ketan Patel, Kiersten Giusto, Charles R. Ashby, Jagadish Koya, Manali Patki, Sandra E. Reznik, Swapna Munnangi
Publikováno v:
Nanomedicine. 14:2835-2851
Aim: Previously, we have shown that inhibition of SphK by the SphK inhibitor-II (SKI II) prevents lipopolysaccharide-induced preterm birth in mice. The aim of this study was to develop a vaginal self-nanoemulsifying drug-delivery system (SNEDDS) for