Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jagadheshan, Hiriyan"'
Autor:
Kishore V.L. Parsa, Bandish Kapadia, Jagadheshan Hiriyan, Prasad Shivarudraiah, Phanithi Prakash Babu, Vasundhara Kain, Neeraja P. Alamuru-Yellapragada, Soma Behera, Parimal Misra, Narmadha Reddy Gangula, Vachana Murunikkara, Sriram Seshadri, Subbareddy Maddika, Sireesh T. Kumar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:1702-1716
Nutritional abundance associated with chronic inflammation and dyslipidemia impairs the functioning of endoplasmic reticulum (ER) thereby hampering cellular responses to insulin. PHLPP1 was identified as a phosphatase which inactivates Akt, the maste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04feaecb4da8b3c7c0ff749ac3e61397
https://doi.org/10.1016/j.bbadis.2018.02.019
https://doi.org/10.1016/j.bbadis.2018.02.019
Autor:
Siddalingesh M. Banakar, Sachidananda Vijayakumar, Mihai Negru, Veeresh P. Veerapur, Jagadheshan Hiriyan, N.V. Thimmaiah, Doddamavattur Shivalingaiah Suhas, Kwashie Eklu-Gadegbeku, Kossi Metowogo, Tumbadi Adinarayanashetty Puneeth, Marian Taulescu, Kodjo Aklikokou, Mabozou Kpemissi, Vivek Chandramohan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 116, Iss, Pp 108961-(2019)
Nephrotoxicity is known to be a major complication during cisplatin chemotherapy in cancer patients. In the present study, the protective effect of a hydroalcoholic extract of Combretum micranthum (CM) against cisplatin (CP)-induced renal damage was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4edd050e39131aa70eb0ecfd778c80d
https://doi.org/10.1016/j.biopha.2019.108961
https://doi.org/10.1016/j.biopha.2019.108961
Autor:
Cynthia Gershome, Ravi K.B. Damarla, Reeba K. Vikramadithyan, Juluri Suresh, Ramanujam Rajagopalan, Ranjan Chakrabarti, Jagadheshan Hiriyan, Parimal Misra, Suryaprakash Raichur
Publikováno v:
British Journal of Pharmacology. 140:527-537
Ragaglitazar [(−) DRF 2725; NNC 61-0029] is a coligand of PPARα and PPARγ. In ob/ob mice, ragaglitazar showed significant reduction in plasma glucose, triglyceride and insulin (ED50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d9015a58b48d456b838f76e0143cc3
https://doi.org/10.1038/sj.bjp.0705463
https://doi.org/10.1038/sj.bjp.0705463
Autor:
Reeba K. Vikramadithyan, Ramanujam Rajagopalan, Juluri Suresh, Ravi K. Babu, Ranjan Chakrabarti, Cynthia Gershome, Parimal Misra, Jagadheshan Hiriyan
Publikováno v:
Obesity Research. 11:292-303
Objective: Preclinical evaluation of DRF 2655, a peroxisome proliferator-activated receptor alpha (PPARα) and PPARγ agonist, as a body-weight lowering, hypolipidemic and euglycemic agent. Research Methods and Procedures: DRF 2655 was studied in dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2d6879ed6270c2a8e84aa624b8dad1
https://doi.org/10.1038/oby.2003.44
https://doi.org/10.1038/oby.2003.44
Autor:
Juluri Suresh, Mamnoor Premkumar, Reeba K. Vikramadithyan, Ravi K.B. Damarla, Ramanujam Rajagopalan, Parimal Misra, Ranjan Chakrabarti, Srinivas R. Datla, Jagadheshan Hiriyan
Publikováno v:
European journal of pharmacology. 491(2-3)
We investigated the biological activity of Dr. Reddy's Research Foundation (DRF) 2519, a benzoxazinone analogue of the thiazolidinedione class of compounds. In the in vitro transactivation assay, DRF 2519 showed interesting dual activation of Peroxis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b936e0978491ef0e1c013bfdd96ef1d5
https://pubmed.ncbi.nlm.nih.gov/15140637
https://pubmed.ncbi.nlm.nih.gov/15140637
Autor:
Ranjan, Chakrabarti, Reeba K, Vikramadithyan, Parimal, Misra, Jagadheshan, Hiriyan, Suryaprakash, Raichur, Ravi K, Damarla, Cynthia, Gershome, Juluri, Suresh, Ramanujam, Rajagopalan
Publikováno v:
British journal of pharmacology. 140(3)
Ragaglitazar [(-) DRF 2725; NNC 61-0029] is a coligand of PPARalpha and PPARgamma. In ob/ob mice, ragaglitazar showed significant reduction in plasma glucose, triglyceride and insulin (ED50 values0.03, 6.1 and0.1 mg kg-1). These effects are three-fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e45b56e0fd2816ddbb11e9bc9fb992c3
https://pubmed.ncbi.nlm.nih.gov/12970088
https://pubmed.ncbi.nlm.nih.gov/12970088
Autor:
Parimal Misra, Janardan K. Reddy, Songtao Yu, Papreddy Kashireddy, Suresh Juluri, Ranjan Chakrabarti, Yijun Zhu, Gopalakrishnan Bolusu, Cynthia Gershome, Rajagopalan Ramanujam, Reeba K. Vikramadithyan, Chao Qi, Jagadheshan Hiriyan, M. Sambasiva Rao, Sailesh Surapureddi, Abdul Rajjak
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 306(2)
PAT5A [5-[4-[N-(2-pyridyl)-(2S)-pyrrolidine-2-methoxyl]phenylmethylene[thiazolidine-2,4-dione, malic acid salt]], a chemically distinct unsaturated thiazolidinedione, activates peroxisome proliferator-activated receptor gamma (PPARgamma) submaximally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116192ef01f777132e3e0d675358dbdb
https://pubmed.ncbi.nlm.nih.gov/12730351
https://pubmed.ncbi.nlm.nih.gov/12730351
Akademický článek
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Autor:
Rajulu, Gavara Govinda, Bhojya Naik, Halehatty Seephya, Viswanadhan, Abhilash, Thiruvengadam, Jayaraman, Rajesh, Kondodiyil, Ganesh, Sambasivam, Jagadheshan, Hiriyan, Kesavan, Poonimangadu Koppolu
Publikováno v:
ChemInform; Jul2014, Vol. 45 Issue 27, pno-no, 1p