Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jagabandhu Das"'
Publikováno v:
2022 IEEE International Conference on Signal Processing and Communications (SPCOM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97755ff272e1d927700b998ff0c72e9e
https://doi.org/10.1109/spcom55316.2022.9840797
https://doi.org/10.1109/spcom55316.2022.9840797
Autor:
Jingwu Duan, Stephen T. Wrobleski, Joel C. Barrish, Jagabandhu Das, Gary L. Schieven, Steven H. Spergel, Charu Chaudhry, Percy H. Carter, John S. Tokarski, Damaso Ovalle, John S. Sack, Aberra Fura, Zhonghui Lu, James Kempson, Luisa Salter-Cid, William J. Pitts, Junqing Guo, Yuval Blatt, John Hynes, Shuqun Lin, Hong Wu, Bin Jiang, Bingwei V. Yang, Javed Khan
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(20)
A useful and novel set of tool molecules have been identified which bind irreversibly to the JAK3 active site cysteine residue. The design was based on crystal structure information and a comparative study of several electrophilic warheads.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c47d1bc032446049ef7f1808408c34
https://pubmed.ncbi.nlm.nih.gov/28927786
https://pubmed.ncbi.nlm.nih.gov/28927786
Autor:
P. Venkateswaran, Jagabandhu Das
Publikováno v:
2016 International Conference on Microelectronics, Computing and Communications (MicroCom).
Specific algorithm simplifies the critical hardware requirement for smart signal processing applications. HASPA is such supervised ANN learning algorithm that specifically designed for multiple antenna based RADAR signal processing. The algorithm is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155d0f29199395a2a1ddc94ffa37cc9c
https://doi.org/10.1109/microcom.2016.7522457
https://doi.org/10.1109/microcom.2016.7522457
Autor:
Jagabandhu Das, P. Venkateswaran
Publikováno v:
2015 IEEE MTT-S International Microwave and RF Conference (IMaRC).
The use of multiple antenna system for wireless communication has gained huge interest during the last decade. Main purpose of this work is to replace the requirement of single antenna based mechanical rotary arrangement and duplexer from conventiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd58082c81076171e97276555b566586
https://doi.org/10.1109/imarc.2015.7411413
https://doi.org/10.1109/imarc.2015.7411413
Autor:
William J. Pitts, Alaric J. Dyckman, Scott H. Watterson, Robert V. Moquin, Kim W. McIntyre, Zheng Yang, Jagabandhu Das, Katy Van Kirk, James R. Burke, David B. Wang-Iverson, Hollie Booth-Lute, James Kempson, Laishun Chen, Charles M. Langevine, Joel C. Barrish, Guchen Yang, Xiaoxia Yang, John H. Dodd, David S. Nirschl, Murray McKinnon, Steven H. Spergel, Mark A. Pattoli, Michael Galella, Kurt R. Gregor, Junquing Guo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:7006-7012
The synthesis, structure-activity relationships (SAR), and biological results of pyridyl-substituted azaindole based tricyclic inhibitors of IKK2 are described. Compound 4m demonstrated potent in vitro potency, acceptable pharmacokinetic and physicoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d20db656b0bd7d293349f9329e548bb
https://doi.org/10.1016/j.bmcl.2011.09.111
https://doi.org/10.1016/j.bmcl.2011.09.111
Autor:
James Kempson, Joel C. Barrish, Laishun Chen, Alaric J. Dyckman, Robert V. Moquin, Kim W. McIntyre, Kathleen M. Gillooly, William J. Pitts, James R. Burke, Steven H. Spergel, Jagabandhu Das, Mark A. Pattoli, Scott H. Watterson, John H. Dodd, Murray McKinnon, Xiao Xia Yang, Junqing Guo, Charles M. Langevine
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:2646-2649
A new series of tricyclic-based inhibitors of IKK have been derived from an earlier lead compound. The synthesis and structure-activity relationships (SAR) are described. Compound 4k inhibited TNF production in rats stimulated with LPS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a3d5262cca9942cd0069b8a7d78124
https://doi.org/10.1016/j.bmcl.2009.03.159
https://doi.org/10.1016/j.bmcl.2009.03.159
Autor:
Charles M. Langevine, Joseph A. Furch, Dominique Belanger, Mark A. Pattoli, Joel C. Barrish, Alaric J. Dyckman, Marco Dodier, James Kempson, Jagabandhu Das, David S. Nirschl, Laishun Chen, Punit Marathe, Kathleen M. Gillooly, Junqing Guo, Robert V. Moquin, John H. Dodd, Murray McKinnon, Anne Marinier, Zheng Yang, Steven H. Spergel, Claude A. Quesnelle, Kim W. McIntyre, Katy Van Kirk, James R. Burke, William J. Pitts, Scott H. Watterson, Alain Martel, Patrice Gill, David B. Wang-Iverson, Tianle Li
Publikováno v:
Journal of Medicinal Chemistry. 52:1994-2005
The design and synthesis of a novel series of oxazole-, thiazole-, and imidazole-based inhibitors of IkappaB kinase (IKK) are reported. Biological activity was improved compared to the pyrazolopurine lead, and the expedient synthesis of the new tricy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4567117bd8910f92df6183547c38087
https://doi.org/10.1021/jm8015816
https://doi.org/10.1021/jm8015816
Autor:
Joel C. Barrish, David J. Shuster, Chunjian Liu, Kim W. McIntyre, Tai-An Lin, Amrita Kamath, Becky Penhallow, Kathleen D. O'Day, Steven B. Kanner, Joseph A. Furch, John H. Dodd, Steven H. Spergel, Hongjian Zhang, James Lin, Robert V. Moquin, Arthur M. Doweyko, John Wityak, Punit Marathe, Jagabandhu Das, Chen Yi Hung
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3706-3712
A series of structurally novel aminothiazole based small molecule inhibitors of Itk were prepared to elucidate their structure-activity relationships (SARs), selectivity, and cell activity in inhibiting IL-2 secretion in a Jurkat T-cell assay. Compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169223aa263063f6df925f2ed71abcbd
https://doi.org/10.1016/j.bmcl.2006.04.060
https://doi.org/10.1016/j.bmcl.2006.04.060
Autor:
Bang-Chi Chen, Suhong Pang, Steven H. Spergel, Leslie Leith, David J. Shuster, John Wityak, Derek J. Norris, Jagabandhu Das, Rulin Zhao, Gary L. Schieven, Kim W. McIntyre, Joel C. Barrish, Rosemary Zhang, Kamelia Behnia, Ding Ren Shen, Sidney Pitt, Arthur M. Doweyko, Ping Chen, Henry F. De Fex
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:6061-6066
A series of substituted 2-(aminoheteroaryl)-thiazole-5-carboxamide analogs have been synthesized as novel, potent inhibitors of the Src-family kinase p56Lck. Among them, compound 2 displayed superior in vitro potency and excellent in vivo efficacy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b919dd207e6828284c8e329093d65a0
https://doi.org/10.1016/j.bmcl.2004.09.093
https://doi.org/10.1016/j.bmcl.2004.09.093
Autor:
John Wityak, Amrita Kamath, Louis J. Lombardo, Ping Chen, John T. Hunt, Ivan Inigo, Stephen Castaneda, Joel C. Barrish, Herbert E. Klei, Robert J. Schmidt, John S. Tokarski, Sidney Pitt, Derek J. Norris, Francis Y. Lee, Jagabandhu Das, Craig Fairchild, Kathy A. Johnston, Punit Marathe, Robert M. Borzilleri, Cornelius Lyndon A M, Suhong Pang, Mei-Li Wen, Russell Peterson, Gary L. Schieven, Kamelia Behnia, David Kan, Arthur M. Doweyko
Publikováno v:
Journal of Medicinal Chemistry. 47:6658-6661
A series of substituted 2-(aminopyridyl)- and 2-(aminopyrimidinyl)thiazole-5-carboxamides was identified as potent Src/Abl kinase inhibitors with excellent antiproliferative activity against hematological and solid tumor cell lines. Compound 13 was o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368da0e6e3d35ffae3cb0ff13f42526f
https://doi.org/10.1021/jm049486a
https://doi.org/10.1021/jm049486a