Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jaffarguriqbal Singh"'
Autor:
Cathy C. Garcia, Lauren Lawres, Sherry Agabiti, Jaffarguriqbal Singh, Alex Tong, Aarthi Venkat, Daniel B. Burkhardt, Rebecca Cardone, Richard G. Kibbey, Smita Krishnaswamy, Mandar D. Muzumdar
Publikováno v:
Cancer Research. 82:C050-C050
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States. Various epidemiologic studies have shown that obesity increases the risk of PDAC. With rising rates of obesity worldwide, it is imperativ
Autor:
Yanixa Quiñones Avilés, Jaffarguriqbal Singh, Wenxue Li, Yong Kong, Yansheng Liu, Mandar Deepak Muzumdar
Publikováno v:
Cancer Research. 82:B063-B063
KRAS is a proto-oncogene found mutated in >90% of pancreatic ductal adenocarcinomas (PDAC) and encodes for a GTPase that mediates signaling transduction through the mitogen-activated protein kinase (MAPK) and PI3K/AKT pathways. Mutations in amino aci
Autor:
Richard F. Dunne, Daniel B. Burkhardt, Xiaojian Zhao, Rebecca L. Cardone, Cathy Garcia, Charles S. Fuchs, Joshua J. Wilhelm, Richard G. Kibbey, Arjun Bhutkar, Jaffarguriqbal Singh, Andressa Dias Costa, Brian M. Wolpin, Lauren Lawres, Albert C. Koong, Kimberly Judith Dorans, Smita Krishnaswamy, Daniel T. Chang, Rebecca Robbins, Jonathan A. Nowak, Vibe Nylander, Sara A. Väyrynen, Aram F. Hezel, Mandar Deepak Muzumdar, Anna L. Gloyn, Melena D. Bellin, Mark I. McCarthy, Ana Babic, Katherine Minjee Chung, Tyler Jacks
Publikováno v:
PMC
SUMMARYObesity is a major modifiable risk factor for pancreatic ductal adenocarcinoma (PDAC), yet how and when obesity contributes to PDAC progression is not well understood. Leveraging an autochthonous mouse model, we demonstrate a causal and revers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290025f60f3dd7717b95582f1b4287a7
https://hdl.handle.net/1721.1/134176
https://hdl.handle.net/1721.1/134176
Autor:
Mandar Deepak Muzumdar, Jaffarguriqbal Singh, Lauren Lawres, Alexander Tong, Smita Krishnaswamy, Sherry Agabiti, Rebecca L. Cardone, Cathy Garcia, Daniel B. Burkhardt, Richard G. Kibbey
Publikováno v:
Cancer Research. 81:LT013-LT013
Obesity is a major modifiable host risk factor for pancreatic ductal adenocarcinoma (PDAC), the third leading cause of cancer death in the United States and a major cause of morbidity and mortality worldwide. Despite the rapid rise in the prevalence